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Longbottom, D., Livingstone, M., Wheelhouse, N., Ensor, H., Rocchi, M., Maley, S., …Dalgleish, M. (2017). Pathogenic outcome following experimental infection of sheep with Chlamydia abortus variant strains LLG and POS. PLoS ONE. doi:10.1371/journal.pone.0177653. ISSN 1932-6203
This study investigated the pathogenesis of two variant strains (LLG and POS) of Chlamydia abortus, in comparison to a typical wild-type strain (S26/3) which is known to be re...
Rees, C. E. D., Doyle, L. & Taylor, C. M. (2017). Listeria monocytogenes. In Foodborne Diseases, 253-276. (3rd). Elsevier. doi:10.1016/b978-0-12-385007-2.00012-7. ISBN 9780123850072
Listeria monocytogenes was first described in 1923. Before 1982, L. monocytogenes was recognized as a cause of abortions and encephalitis in many animals (particularly cattle ...
Wheelhouse, N., Flockhart, A., Aitchison, K., Livingstone, M., Finlayson, J., Flachon, V., …Longbottom, D. (2016). Experimental challenge of pregnant cattle with the putative abortifacient Waddlia chondrophila. Scientific Reports. 6, 37150. doi:10.1038/srep37150. ISSN 2045-2322
Waddlia chondrophila is a Gram-negative intracellular bacterial organism that is related to classical chlamydial species and has been implicated as a cause of abortion in catt...
Society of Applied Microbiology
MinION sequencing of bacterial isolates
Biotechnology and Biological Sciences Research Council
Development of a UK-Brazil partnership to tackle fungal food spoilage and improve food security
20 April 2017
21 April 2017
The Biological Visualisation Community's 3rd Annual Meeting takes place at Craiglockhart Campus in Edinburgh on 20th-21st April 2017.
This two day meeting compri...
Lecturer in Biomedical Science
Wani, S., Maker, J., Thompson, J., Barnes, J. & Singleton, I. (2015). Effect of Ozone Treatment on Inactivation of Escherichia coli and Listeria sp. on Spinach. Agriculture. 5(2), 155-169. doi:10.3390/agriculture5020155
The efficacy of “gaseous” ozone in reducing numbers and re-growth of food-borne pathogens, (Escherichia coli and Listeria spp.), on leafy salads was investigated using spinach...
Fraser, J. A. (2009). Regulation and Function of the Original p53- Inducible p21 Gene. In p53; Molecular Biology Intelligence Unit, 100-116. Springer Science + Business Media. doi:10.1007/978-1-4419-8231-5_7. ISBN 978-1-4419-8230-8; 978-1-4419-8231-5
P21 is a well known regulator of cell cycle progression through its inhibitory actions on Cyclin dependent kinases, (Cdk)/cyclin complexes, and DNA replication via its binding...
Bennett, H. J., Pearce, D. M., Glenn, S., Taylor, C. M., Kuhn, M., Sonenshein, A. L., …Roberts, I. S. (2007). Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulence. Molecular Microbiology. 63, 1453--1467. doi:10.1111/j.1365-2958.2007.05597.x. ISSN 0950-382X
Listeria monocytogenes is a Gram-positive intracellular parasite and the causative organism of human listeriosis. In this article we demonstrate that L. monocytogenes encodes ...
Lee, M., Kim, M., Singleton, I., Goodfellow, M. & Lee, S. (2006). Enhanced biodegradation of diesel oil by a newly identified Rhodococcus baikonurensis EN3 in the presence of mycolic acid. Journal of applied microbiology. 100(2), 325-333. doi:10.1111/j.1365-2672.2005.02756.x. ISSN 1364-5072
Aims: The aim of the present study was to isolate and characterize a bacterium, strain EN3, capable of using diesel oil as a major carbon and energy source, and to analyse th...
Taylor, C. M., Goldrick, M., Lord, L. & Roberts, I. S. (2005). Mutations in the waaR Gene of Escherichia coli Which Disrupt Lipopolysaccharide Outer Core Biosynthesis Affect Cell Surface Retention of Group 2 Capsular Polysaccharides. Journal of Bacteriology. 188(3), 1165-1168. doi:10.1128/JB.188.3.1165-1168.2006. ISSN 0021-9193
On the basis of increased resistance to K5 capsule-specific bacteriophage, a waaR transposon mutant defective in the biosynthesis of lipopolysaccharide outer core was isolated...
Vizard, C. G., Rimmer, D. L., Pless-Mulloli, T., Singleton, I. & Air, V. S. (2005). Identifying contemporary and historic sources of soil polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in an industrial urban setting. Science of the Total Environment. 370(1), 61 - 69. doi:10.1016/j.scitotenv.2006.06.006. ISSN 0048-9697
A study of soil polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/F) concentrations was undertaken in the vicinity of a municipal solid waste incinerat...
O’Mahony, M. M., Dobson, A. D., Barnes, J. D. & Singleton, I. (2006). The use of ozone in the remediation of polycyclic aromatic hydrocarbon contaminated soil. Chemosphere. 63(2), 307-314. doi:10.1016/j.chemosphere.2005.07.018. ISSN 0045-6535
The potential of using ozone for the removal of phenanthrene from several different soils, both alone and in combination with biodegradation using a microbial inoculant (Pseud...