Research Output
NuMA is required for proper spindle assembly and chromosome alignment in prometaphase
  NuMA is a protein that has been previously shown to play a role in focusing microtubules at the mitotic spindle poles. However, most previous work relies on experimental methods that might cause dominant side effects on spindle formation, such as microinjection of antibodies, overexpression of mutant protein, or immunodepletion of NuMA-containing protein complexes.

  • Type:

    Article

  • Date:

    28 April 2009

  • Publication Status:

    Published

  • DOI:

    10.1186/1756-0500-2-64

  • Cross Ref:

    1756-0500-2-64

  • Library of Congress:

    QR180 Immunology

  • Dewey Decimal Classification:

    572 Biochemistry

Citation

Haren, L., Gnadt, N., Wright, M., & Merdes, A. (2009). NuMA is required for proper spindle assembly and chromosome alignment in prometaphase. BMC Research Notes, 2, 1-6. https://doi.org/10.1186/1756-0500-2-64

Authors

Keywords

NuMA, microtubules, mitotic spindle poles, immunodepletion,

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