David Muggeridge
david muggeridge

Dr David Muggeridge

Lecturer

Biography

Dr David Muggeridge is a Lecturer in Exercise Physiology at Edinburgh Napier University and the Research Degrees Lead for the School of Applied Sciences. He is part of the sport, exercise and health research group and teach across the sport and exercise science programmes. He is currently the module leader for Intermediate Exercise Physiology (Level 9) and contributes to Foundations of sport and Exercise science (level 7), Introduction to Exercise Physiology (level 8) and Advanced Exercise Physiology (Level 10).

David graduated from his undergraduate B.Sc with Honours in Sport Science at Kingston University in 2011. He subsequently completed his Ph.D in Exercise Physiology at University of the West of Scotland in 2015, investigating the influence of dietary nitrate supplementation and UV-A light exposure on parameters of exercise in healthy adult males. Postdoctoral and research fellow positions followed in the area of cardiovascular and digital health with focus on measurement, physical activity and exercise and their relation to human physiology.

Dr Muggeridge's research at the university is primarily focussed within the Centre for Cardiovascular Health. He is currently leading research into the effects of sunlight exposure and seasonal variation in vascular function. He currently supervises a PhD project exploring the Seasonal Utilisation of Nitric Oxide, funded by the School of Applied Sciences and School of Health and Social Care. Dr Muggeridge also supports additional projects, including leading research with Hibernian Football club and as a Co-investigator for the SCAD Recovery project, funded by the Burdett Trust for Nursing.

David is an active member of the Physiological Society and is the ENU University Rep to the society.

Themes

Esteem

Advisory panels and expert committees or witness

  • COST VascAgeNet

 

Conference Organising Activity

  • Conference organiser and committee member - Scottish Cardiovascular Forum

 

Grant Reviewer

  • The Physiological Society

 

Membership of Professional Body

  • The Physiological Society University Representative
  • The Physiological Society Full Member

 

Reviewing

  • Journal of Applied Physiology
  • Scientific Reports
  • International Journal of Sports Nutrition and Exercise Metabolism
  • Sports Medicine
  • Nitric Oxide
  • Nutrients

 

Date


29 results

High-intensity interval training in patients with heart failure

Journal Article
Callum, K. J., Gorely, T., Crabtree, D. R., Muggeridge, D. J., & Leslie, S. J. (2020)
High-intensity interval training in patients with heart failure. British Journal of Cardiac Nursing, 15(4), 1-13. https://doi.org/10.12968/bjca.2019.0058
Cardiac rehabilitation is a key component in the secondary prevention of cardiovascular disease. However, uptake and adherence to programmes is suboptimal, especially for pati...

Exploring the mechanisms by which nitrate supplementation improves skeletal muscle contractile function: one fibre at a time

Journal Article
McIlvenna, L. C., Muggeridge, D. J., & Whitfield, J. (2020)
Exploring the mechanisms by which nitrate supplementation improves skeletal muscle contractile function: one fibre at a time. Journal of Physiology, 598(1), 25-27. https://doi.org/10.1113/jp279118
No abstract available.

Co-ingestion of Antioxidant Drinks With an Unhealthy Challenge Meal Fails to Prevent Post-prandial Endothelial Dysfunction: An Open-Label, Crossover Study in Older Overweight Volunteers

Journal Article
Muggeridge, D. J., Goszcz, K., Treweeke, A., Adamson, J., Hickson, K., Crabtree, D., & Megson, I. L. (2019)
Co-ingestion of Antioxidant Drinks With an Unhealthy Challenge Meal Fails to Prevent Post-prandial Endothelial Dysfunction: An Open-Label, Crossover Study in Older Overweight Volunteers. Frontiers in Physiology, 10, https://doi.org/10.3389/fphys.2019.01293
Eating a high calorie meal is known to induce endothelial dysfunction and it is reported that consuming drinks rich in antioxidants may be protective against this. In this stu...

Dietary nitrate supplementation alters the oral microbiome but does not improve the vascular responses to an acute nitrate dose

Journal Article
Burleigh, M., Liddle, L., Muggeridge, D. J., Monaghan, C., Sculthorpe, N., Butcher, J., …Easton, C. (2019)
Dietary nitrate supplementation alters the oral microbiome but does not improve the vascular responses to an acute nitrate dose. Nitric Oxide: Biology and Chemistry, 89, 54-63. https://doi.org/10.1016/j.niox.2019.04.010
Nitrate (NO3−) contained in food and beverages can transiently increase nitric oxide (NO) availability following a stepwise reduction to nitrite (NO2−) by commensal bacteria i...

Lower limb ischemic preconditioning combined with dietary nitrate supplementation does not influence time-trial performance in well-trained cyclists

Journal Article
McIlvenna, L. C., Muggeridge, D. J., Forrest (Nee Whyte), L. J., Monaghan, C., Liddle, L., Burleigh, M. C., …Easton, C. (2019)
Lower limb ischemic preconditioning combined with dietary nitrate supplementation does not influence time-trial performance in well-trained cyclists. Journal of Science and Medicine in Sport, 22(7), 852-857. https://doi.org/10.1016/j.jsams.2019.01.011
OBJECTIVES: Dietary nitrate (NO3-) supplementation and ischaemic preconditioning (IPC) can independently improve exercise performance. The purpose of this study was to explore...

Variability in nitrate-reducing oral bacteria and nitric oxide metabolites in biological fluids following dietary nitrate administration: An assessment of the critical difference

Journal Article
Liddle, L., Burleigh, M. C., Monaghan, C., Muggeridge, D. J., Sculthorpe, N., Pedlar, C. R., …Easton, C. (2019)
Variability in nitrate-reducing oral bacteria and nitric oxide metabolites in biological fluids following dietary nitrate administration: An assessment of the critical difference. Nitric Oxide: Biology and Chemistry, 83, 1-10. https://doi.org/10.1016/j.niox.2018.12.003
There is conflicting evidence on whether dietary nitrate supplementation can improve exercise performance. This may arise from the complex nature of nitric oxide (NO) metaboli...

To clot or not to clot? That is a free radical question

Journal Article
Crabtree, D. R., Muggeridge, D., Leslie, S. J., Megson, I. L., & Cobley, J. N. (2018)
To clot or not to clot? That is a free radical question. Journal of Physiology, 596(20), 4805-4806. https://doi.org/10.1113/jp276786
nravelling the biological roles of reactive oxygen species (ROS) is challenging (Murphy et al. 2011). There are three key challenges: (1) the global term ‘ROS’ subsumes chemic...

Salivary nitrite production is elevated in individuals with a higher abundance of oral nitrate-reducing bacteria

Journal Article
Burleigh, M. C., Liddle, L., Monaghan, C., Muggeridge, D. J., Sculthorpe, N., Butcher, J. P., …Easton, C. (2018)
Salivary nitrite production is elevated in individuals with a higher abundance of oral nitrate-reducing bacteria. Free Radical Biology and Medicine, 120, 80-88. https://doi.org/10.1016/j.freeradbiomed.2018.03.023
Nitric oxide (NO) can be generated endogenously via NO synthases or via the diet following the action of symbiotic nitrate-reducing bacteria in the oral cavity. Given the impo...

The effects of two different doses of ultraviolet-A light exposure on nitric oxide metabolites and cardiorespiratory outcomes

Journal Article
Monaghan, C., McIlvenna, L. C., Liddle, L., Burleigh, M., Weller, R. B., Fernandez, B. O., …Easton, C. (2018)
The effects of two different doses of ultraviolet-A light exposure on nitric oxide metabolites and cardiorespiratory outcomes. European Journal of Applied Physiology, 118(5), 1043-1052. https://doi.org/10.1007/s00421-018-3835-x
PURPOSE: The present study investigated different doses of ultraviolet-A (UV-A) light on plasma nitric oxide metabolites and cardiorespiratory variables. METHODS: Ten healthy...

Untargeted Metabolomics Profiling of an 80.5 km Simulated Treadmill Ultramarathon

Journal Article
Howe, C. C., Alshehri, A., Muggeridge, D., Mullen, A., Boyd, M., Spendiff, O., …Watson, D. (2018)
Untargeted Metabolomics Profiling of an 80.5 km Simulated Treadmill Ultramarathon. Metabolites, 8(1), https://doi.org/10.3390/metabo8010014
Metabolomic profiling of nine trained ultramarathon runners completing an 80.5 km self-paced treadmill-based time trial was carried out. Plasma samples were obtained from veno...

Pre-Napier Funded Projects

  • 1385AG : Feasibility testing of wearable cardiac monitoring technologies
  • SiHealth - NaturAgeing
  • Lenus Digital Health Platform
  • Assessing snap40's health monitoring solution amongst healthy adults (ASHMANA)

Current Post Grad projects

Previous Post Grad projects

Non-Napier PhD or MSc by Research supervisions

  • Miss Nikki Thomson