Lindsay Ramage

Dr Lindsay Ramage

Leader of Research Information Management

L.Ramage@napier.ac.uk

About me
Activity
Outputs
Post Grad

Biography

I am the Leader of Research Information Management within the Research and Innovation Office (RIO). This involves supporting our research management system and research data management for the University. My team also works in the areas of post award management and REF.

Previously I was a Research and Innovation Manager within RIO at Edinburgh Napier University and the Research Office at Edinburgh University both supporting research and innovation funding proposal development.

Prior to working in research administration and management I was a postdoctoral researcher for 8 years at Universities including Edinburgh University, Jagellonian University and the University of Hertfordshire. My research areas covered cell signalling interactions and pathways in disease pathology.

Esteem

Invited Speaker

Conference Talk, EARMA:Edinburgh Napier University and Worktribe develop and implement an end-to-end research management system supporting the full research cycle
Conference talk, ARMA:Edinburgh Napier University and Worktribe develop and implement an end-to-end research management system supporting the full research cycle
Conference talk: Involvement of NMDAR in chondrocyte cell death and matrix degeneration
Seminar: PM10 induces the expression of CRP and Hsp70 in human lung epithelial cell line, A549
Seminar: Protein Expression in carbon black and ultrafine carbon black treated cells
Conference talk: The effects of carbon black and ultrafine carbon black on expression of pro-inflammatory proteins, CRP and Hsp70, in A549 cells

Reviewing

Journal reviewer: Journal of Biomechanics
Journal reviewer: Journal of Research in Environmental Science and Toxicology
Journal reviewer: Osteoarthritis and Cartilage
Journal reviewer: BMC Research Notes
Journal reviewer: Swiss Medical Weekly
Journal reviewer: Experimental Physiology
Journal reviewer: Medical Science Monitor
Journal reviewer: Respiratory Research
Journal reviewer: Mediators of Inflammation
Journal reviewer: American Journal of Physiology- Lung Cellular and Molecular Physiology
Journal reviewer: British Journal of Pharamacology
Journal reviewer: Journal of Inflammation

Fellowships and Awards

Fellowship funded by EU 6th FP project: SP6MTKD-CT-2006-042586.

Expression of pro-inflammatory proteins in the lung epithelial cell line A549, in response to cytokine, and environmental particle exposure.

Ramage, L. environmental particle exposure. (Thesis)
Ramage, L. environmental particle exposure. (Thesis)

This thesis investigates the effects of various inflammatory stimuli, including cytokines and air pollution particles, on the expression and secretion of various proinflammato...

2003
Increasing academic engagement with the research repository – the value of an integrated system

Ramage, L., & Gibson, L. (2017, August). Increasing academic engagement with the research repository – the value of an integrated system. Poster presented at Repository Fringe 2917, University of Edinburgh
Ramage, L., & Gibson, L. (2017, August). Increasing academic engagement with the research repository – the value of an integrated system. Poster presented at Repository Fringe 2917, University of Edinburgh

In August 2016 Edinburgh Napier rolled out their new end-to-end research management system. This allows academics self-service access to record and manage research information...

2017
Implementation of an end-to-end research management system

Ramage, L. (2017, June). Implementation of an end-to-end research management system. Poster presented at ARMA annual conference, Liverpool, UK
Ramage, L. (2017, June). Implementation of an end-to-end research management system. Poster presented at ARMA annual conference, Liverpool, UK

In the past 12-18 months we, at Edinburgh Napier University, have implemented an end to end research management system. We have been involved on the development of the resear...

2017
P088 Involvement of NMDAR in chondrocyte cell death and matrix degeneration

Ramage, L., Hardingham, G. & Salter, D. (2009, June). P088 Involvement of NMDAR in chondrocyte cell death and matrix degeneration. Paper presented at 2nd Joint meeting of the Bone Research Society and the British Society for Matrix Biology, London
Ramage, L., Hardingham, G. & Salter, D. (2009, June). P088 Involvement of NMDAR in chondrocyte cell death and matrix degeneration. Paper presented at 2nd Joint meeting of the Bone Research Society and the British Society for Matrix Biology, London

NMDA receptors (NMDAR) are expressed by chondrocytes in articular cartilage although their function is yet to be fully understood. NMDAR are ionotropic glutamate receptors whi...

2009
NMDA receptor function in osteoarthritic chondrocytes is dependent on B1 integins

Ramage, L., Hardingham, G. E., & Salter, D. M. (2008, May). NMDA receptor function in osteoarthritic chondrocytes is dependent on B1 integins. Poster presented at Scottish society of experimental medicine, Dundee, UK
Ramage, L., Hardingham, G. E., & Salter, D. M. (2008, May). NMDA receptor function in osteoarthritic chondrocytes is dependent on B1 integins. Poster presented at Scottish society of experimental medicine, Dundee, UK

No abstract available - details of conference poster.

2008
Expression of functional NMDA receptors in human osteoarthritic chondrocytes

Ramage, L., Hardingham, G., & Salter, D. (2006, November). Expression of functional NMDA receptors in human osteoarthritic chondrocytes. Poster presented at Scottish Society for Experimental Medicine, Edinburgh, UK
Ramage, L., Hardingham, G., & Salter, D. (2006, November). Expression of functional NMDA receptors in human osteoarthritic chondrocytes. Poster presented at Scottish Society for Experimental Medicine, Edinburgh, UK

No abstract available - details of conference poster.

2006
A032 Apoptosis induced by Paclitaxel, tobacco smoke condensate and hydrogen peroxide in lung epithelial cells (A549)

Ramage, L., Jones, A., & Whelan, C. (2004). A032 Apoptosis induced by Paclitaxel, tobacco smoke condensate and hydrogen peroxide in lung epithelial cells (A549). Inflammation Research, 53(S3), (S207-S230). doi:10.1007/bf03353882. ISSN 1023-3830
Ramage, L., Jones, A., & Whelan, C. (2004). A032 Apoptosis induced by Paclitaxel, tobacco smoke condensate and hydrogen peroxide in lung epithelial cells (A549). Inflammation Research, 53(S3), (S207-S230). doi:10.1007/bf03353882. ISSN 1023-3830

Cigarette smoke is known to be a complex mixture of >4000 constituents dispersed between the volatile and non-volatile phase, and inhaled exposure causes lung inflammation and...

2004
Use of the BioGRID Database for Analysis of Yeast Protein and Genetic Interactions

Oughtred, R., Chatr-aryamontri, A., Breitkreutz, B., Chang, C. S., Rust, J. M., Theesfeld, C. L., …Tyers, M. (2015). Use of the BioGRID Database for Analysis of Yeast Protein and Genetic Interactions. Cold Spring Harbor protocols. 2016(1), pdb.prot088880. doi:10.1101/pdb.prot088880. ISSN 1940-3402
Oughtred, R., Chatr-aryamontri, A., Breitkreutz, B., Chang, C. S., Rust, J. M., Theesfeld, C. L., …Tyers, M. (2015). Use of the BioGRID Database for Analysis of Yeast Protein and Genetic Interactions. Cold Spring Harbor protocols. 2016(1), pdb.prot088880. doi:10.1101/pdb.prot088880. ISSN 1940-3402

The BioGRID database is an extensive repository of curated genetic and protein interactions for the budding yeast Saccharomyces cerevisiae, the fission yeast Schizosaccharomyc...

2016
BioGRID: A Resource for Studying Biological Interactions in Yeast: Table 1.

Oughtred, R., Chatr-aryamontri, A., Breitkreutz, B., Chang, C. S., Rust, J. M., Theesfeld, C. L., …Tyers, M. (2015). BioGRID: A Resource for Studying Biological Interactions in Yeast: Table 1. Cold Spring Harbor protocols. 2016(1), pdb.top080754. doi:10.1101/pdb.top080754. ISSN 1940-3402
Oughtred, R., Chatr-aryamontri, A., Breitkreutz, B., Chang, C. S., Rust, J. M., Theesfeld, C. L., …Tyers, M. (2015). BioGRID: A Resource for Studying Biological Interactions in Yeast: Table 1. Cold Spring Harbor protocols. 2016(1), pdb.top080754. doi:10.1101/pdb.top080754. ISSN 1940-3402

The Biological General Repository for Interaction Datasets (BioGRID) is a freely available public database that provides the biological and biomedical research communities wit...

2015
The BioGRID interaction database: 2015 update

Chatr-aryamontri, A., Breitkreutz, B., Oughtred, R., Boucher, L., Heinicke, S., Chen, D., …Tyers, M. (2015). The BioGRID interaction database: 2015 update. Nucleic Acids Research, 43(D1), D470-D478. doi:10.1093/nar/gku1204
Chatr-aryamontri, A., Breitkreutz, B., Oughtred, R., Boucher, L., Heinicke, S., Chen, D., …Tyers, M. (2015). The BioGRID interaction database: 2015 update. Nucleic Acids Research, 43(D1), D470-D478. doi:10.1093/nar/gku1204

The Biological General Repository for Interaction Datasets (BioGRID: http://thebiogrid.org) is an open access database that houses genetic and protein interactions curated fro...

2014
Monocyte chemoattractant protein-induced protein 1 impairs adipogenesis in 3T3-L1 cells

Lipert, B., Wegrzyn, P., Sell, H., Eckel, J., Winiarski, M., Budzynski, A., …Jura, J. (2014). Monocyte chemoattractant protein-induced protein 1 impairs adipogenesis in 3T3-L1 cells. BBA - Molecular Cell Research. 1843(4), 780-788. doi:10.1016/j.bbamcr.2014.01.001. ISSN 0167-4889
Lipert, B., Wegrzyn, P., Sell, H., Eckel, J., Winiarski, M., Budzynski, A., …Jura, J. (2014). Monocyte chemoattractant protein-induced protein 1 impairs adipogenesis in 3T3-L1 cells. BBA - Molecular Cell Research. 1843(4), 780-788. doi:10.1016/j.bbamcr.2014.01.001. ISSN 0167-4889

Monocyte chemoattractant protein-induced protein 1 (MCPIP1) encoded by the ZC3H12a gene (also known as Regnase-1) is involved in the regulation of degradation of mRNA of infla...

2014
The BioGRID interaction database: 2013 update

Chatr-aryamontri, A., Breitkreutz, B., Heinicke, S., Boucher, L., Winter, A., Stark, C., …Tyers, M. (2013). The BioGRID interaction database: 2013 update. Nucleic Acids Research, 41(D1), D816-D823. doi:10.1093/nar/gks1158
Chatr-aryamontri, A., Breitkreutz, B., Heinicke, S., Boucher, L., Winter, A., Stark, C., …Tyers, M. (2013). The BioGRID interaction database: 2013 update. Nucleic Acids Research, 41(D1), D816-D823. doi:10.1093/nar/gks1158

The Biological General Repository for Interaction Datasets (BioGRID: http//thebiogrid.org) is an open access archive of genetic and protein interactions that are curated from ...

2012
Integrins and extracellular matrix in mechanotransduction

Ramage, L. (2011). Integrins and extracellular matrix in mechanotransduction. Cell Health and Cytoskeleton, 2012(4), 1-9. doi:10.2147/chc.s21829
Ramage, L. (2011). Integrins and extracellular matrix in mechanotransduction. Cell Health and Cytoskeleton, 2012(4), 1-9. doi:10.2147/chc.s21829

Integrins are a family of cell surface receptors which mediate cell–matrix and cell–cell adhesions. Among other functions they provide an important mechanical link between the...

2011
Signalling cascades in mechanotransduction: cell-matrix interactions and mechanical loading

Ramage, L., Nuki, G., & Salter, D. M. (2009). Signalling cascades in mechanotransduction: cell-matrix interactions and mechanical loading. Scandinavian Journal of Medicine and Science in Sports, 19(4), 457-469. doi:10.1111/j.1600-0838.2009.00912.x
Ramage, L., Nuki, G., & Salter, D. M. (2009). Signalling cascades in mechanotransduction: cell-matrix interactions and mechanical loading. Scandinavian Journal of Medicine and Science in Sports, 19(4), 457-469. doi:10.1111/j.1600-0838.2009.00912.x

Mechanical loading of articular cartilage stimulates the metabolism of resident chondrocytes and induces the synthesis of molecules to maintain the integrity of the cartilage....

2009
161 NMDA receptor function in osteoarthritic chondrocytes is dependent on β1 integrins

Ramage, L., Hardingham, G. & Salter, D. (2008). 161 NMDA receptor function in osteoarthritic chondrocytes is dependent on β1 integrins. Osteoarthritis and Cartilage. 16(S4), S82. doi:10.1016/s1063-4584(08)60207-1. ISSN 1063-4584
Ramage, L., Hardingham, G. & Salter, D. (2008). 161 NMDA receptor function in osteoarthritic chondrocytes is dependent on β1 integrins. Osteoarthritis and Cartilage. 16(S4), S82. doi:10.1016/s1063-4584(08)60207-1. ISSN 1063-4584

Purpose: Osteoarthritis (OA) is associated with abnormal loading of articular joints. In normal joints physiological loading maintains structure and function of cartilage and ...

2008
NMDA receptor expression and activity in osteoarthritic human articular chondrocytes

Ramage, L., Martel, M., Hardingham, G. E. & Salter, D. M. (2008). NMDA receptor expression and activity in osteoarthritic human articular chondrocytes. Osteoarthritis and Cartilage. 16(12), 1576-1584. doi:10.1016/j.joca.2008.04.023. ISSN 1063-4584
Ramage, L., Martel, M., Hardingham, G. E. & Salter, D. M. (2008). NMDA receptor expression and activity in osteoarthritic human articular chondrocytes. Osteoarthritis and Cartilage. 16(12), 1576-1584. doi:10.1016/j.joca.2008.04.023. ISSN 1063-4584

Objective: Classical neuronal signalling molecules such as substance P and glutamate have been identified in cartilage and have roles in regulation of chondrocyte function. Th...

2008
P186 Expression of functional NMDA receptors in human OA chondrocytes

Ramage, L., Martel, M., Hardingham, G. & Salter, D. (2007). P186 Expression of functional NMDA receptors in human OA chondrocytes. Osteoarthritis and Cartilage. 14(Supp. B), S108. doi:10.1016/s1063-4584(07)60638-4. ISSN 1063-4584
Ramage, L., Martel, M., Hardingham, G. & Salter, D. (2007). P186 Expression of functional NMDA receptors in human OA chondrocytes. Osteoarthritis and Cartilage. 14(Supp. B), S108. doi:10.1016/s1063-4584(07)60638-4. ISSN 1063-4584

Purpose: Classical neuronal signalling molecules such as substance P and glutamate have been identified in cartilage and are being shown to have roles in regulation of chondro...

2007
P214 NMDA receptor signalling in human osteoarthritic chondrocytes.

Ramage, L., Hardingham, G. & Salter, D. (2006). P214 NMDA receptor signalling in human osteoarthritic chondrocytes. Osteoarthritis and Cartilage. 15, B142. doi:10.1016/s1063-4584(07)61569-6. ISSN 1063-4584
Ramage, L., Hardingham, G. & Salter, D. (2006). P214 NMDA receptor signalling in human osteoarthritic chondrocytes. Osteoarthritis and Cartilage. 15, B142. doi:10.1016/s1063-4584(07)61569-6. ISSN 1063-4584

Purpose: Human OA chondrocytes are known to express several subunits of the NMDA receptor (NMDAR), a neuronal signalling molecule. This study analyses downstream activation ev...

2006
Induction of apoptosis with tobacco smoke and related products in A549 lung epithelial cells in vitro

Ramage, L., Jones, A. C. & Whelan, C. J. (2006). Induction of apoptosis with tobacco smoke and related products in A549 lung epithelial cells in vitro. Journal of Inflammation. 3(1), 3. doi:10.1186/1476-9255-3-3
Ramage, L., Jones, A. C. & Whelan, C. J. (2006). Induction of apoptosis with tobacco smoke and related products in A549 lung epithelial cells in vitro. Journal of Inflammation. 3(1), 3. doi:10.1186/1476-9255-3-3

Background This study has investigated the ability of tobacco smoke, and ingredients of tobacco smoke, to induce apoptosis in the airway epithelial cell line A549. Method A549...

2006
Expression of C-reactive protein in human lung epithelial cells and up-regulation by cytokines and carbon particles.

Ramage, L., Proudfoot, L. & Guy, K. (2004). Expression of C-reactive protein in human lung epithelial cells and up-regulation by cytokines and carbon particles. Inhalation toxicology. 16, 607-613. doi:10.1080/08958370490464599. ISSN 1091-7691
Ramage, L., Proudfoot, L. & Guy, K. (2004). Expression of C-reactive protein in human lung epithelial cells and up-regulation by cytokines and carbon particles. Inhalation toxicology. 16, 607-613. doi:10.1080/08958370490464599. ISSN 1091-7691

C-reactive protein (CRP) is the prototypic human acute-phase protein and is found at increased levels in the blood during episodes of inflammation. CRP was generally thought t...

2004
Expression of C-reactive protein and heat shock protein-70 in the lung epithelial cell line A549, in response to PM10 exposure

Ramage, L. & Guy, K. (2004). Expression of C-reactive protein and heat shock protein-70 in the lung epithelial cell line A549, in response to PM10 exposure. Inhalation Toxicology. 16, 447-452. doi:10.1080/08958370490439614. ISSN 0895-8378
Ramage, L. & Guy, K. (2004). Expression of C-reactive protein and heat shock protein-70 in the lung epithelial cell line A549, in response to PM10 exposure. Inhalation Toxicology. 16, 447-452. doi:10.1080/08958370490439614. ISSN 0895-8378

Increased levels of C-reactive protein (CRP) and heat-shock protein-70 (Hsp70) in plasma are known to be associated with an increased risk of cardiovascular disease. In this s...

2004

Previous Post Grad projects

Expression of proinflammatory proteins in the lung epithelial cell line A549, in response to cytokine and environmental particle exposure - Dr Lindsay Ramage (Student), Keith Guy, Dr Lorna Proudfoot

Doctorate

2000 to 2004

Lindsay Ramage

Dr Lindsay Ramage

Biography

Esteem

Invited Speaker

Reviewing

Fellowships and Awards

Expression of pro-inflammatory proteins in the lung epithelial cell line A549, in response to cytokine, and environmental particle exposure.

Increasing academic engagement with the research repository – the value of an integrated system

Implementation of an end-to-end research management system

P088 Involvement of NMDAR in chondrocyte cell death and matrix degeneration

NMDA receptor function in osteoarthritic chondrocytes is dependent on B1 integins

Expression of functional NMDA receptors in human osteoarthritic chondrocytes

A032 Apoptosis induced by Paclitaxel, tobacco smoke condensate and hydrogen peroxide in lung epithelial cells (A549)

Use of the BioGRID Database for Analysis of Yeast Protein and Genetic Interactions

BioGRID: A Resource for Studying Biological Interactions in Yeast: Table 1.

The BioGRID interaction database: 2015 update

Monocyte chemoattractant protein-induced protein 1 impairs adipogenesis in 3T3-L1 cells

The BioGRID interaction database: 2013 update

Integrins and extracellular matrix in mechanotransduction

Signalling cascades in mechanotransduction: cell-matrix interactions and mechanical loading

161 NMDA receptor function in osteoarthritic chondrocytes is dependent on β1 integrins

NMDA receptor expression and activity in osteoarthritic human articular chondrocytes

P186 Expression of functional NMDA receptors in human OA chondrocytes

P214 NMDA receptor signalling in human osteoarthritic chondrocytes.

Induction of apoptosis with tobacco smoke and related products in A549 lung epithelial cells in vitro

Expression of C-reactive protein in human lung epithelial cells and up-regulation by cytokines and carbon particles.

Expression of C-reactive protein and heat shock protein-70 in the lung epithelial cell line A549, in response to PM10 exposure

Previous Post Grad projects

Expression of proinflammatory proteins in the lung epithelial cell line A549, in response to cytokine and environmental particle exposure - Dr Lindsay Ramage (Student), Keith Guy, Dr Lorna Proudfoot