Luke Holman
luke holman

Dr Luke Holman

Associate Professor

Biography

I am an Associate Professor based at Edinburgh Napier University. My research covers a wide range of topics, including evolution, sexual selection, animal communication, ‘gene drives’ (genes that bias the mechanisms of inheritance to favour their own transmission), the representation of women in STEM careers, and ‘meta-science’ (i.e. research about the process of science itself). I combine empirical work on insects such as fruitflies and social insects (bees/ants/wasps) with theoretical models, modern genetics methods (e.g. GWAS, methylome sequencing, transcriptome sequencing), meta-analysis, and computational text mining of large datasets.

Following my BSc and PhD at the University of Sheffield, I moved to Copenhagen University and won a Marie Curie Fellowship, where I primarily researched queen pheromones in the social insects (including the discoveries of the first queen pheromones that regulate worker sterility in ants, wasps, and bumblebees). I then moved to Australian National University in Canberra, initially as post-doc and then later as an independent researcher funded by a 3-year Discovery Early Career Researcher Award (DECRA) fellowship. My research in Canberra focused on sexual selection and diverse topics in evolutionary biology. In 2016, I was appointed to a permanent Senior Lecturer position at the University of Melbourne, where I conducted evolutionary biology research and led undergraduate modules on evolution and statistics. At Melbourne my research group focused on empirical research on fruit flies and honeybees, as well as computational topics.

I moved to Edinburgh Napier University in January 2021. Thus far I have primarily focused on evolutionary genomics analysis of large datasets from humans, fruit flies, and honeybees, as well as developing our teaching in the subject areas of animal behaviour, research methods, and statistics. I have lead three modules, namely Research Methods (which comprises a dissertation and also statistics and R coding), the version of Research Methods that is delivered at SPECTRUM in Sri Lanka, and Animal Behaviour (which comprises lectures, tutorials, coursework and an essay assignment). I also lecture in Advances in Animal Behaviour (on specialised topics in behavioural ecology), Scientific Enquiry (on statistics), and Genes & Inheritance (on population genetics), supervise 4th year Research Project students, and co-teach the Portugal field course for Terrestrial Field Biology.

I am also the Commissioning Editor of the Journal of Evolutionary Biology, a busy role that involves commissioning special features for the journal. I am also active in the scientific society associated with this journal, the European Society for Evolutionary Biology (e.g. I chair a scheme called the Progress Meetings in Evolutionary Biology, which competitively funds research synthesis meetings).

Please see my personal webpage, www.lukeholman.org, for more information.

Date


66 results

An X-linked meiotic drive allele has strong, recessive fitness costs in female Drosophila pseudoobscura

Journal Article
Larner, W., Price, T., Holman, L., & Wedell, N. (2019)
An X-linked meiotic drive allele has strong, recessive fitness costs in female Drosophila pseudoobscura. Proceedings of the Royal Society B: Biological Sciences, 286(1916), https://doi.org/10.1098/rspb.2019.2038
Selfish ‘meiotic drive’ alleles are transmitted to more than 50% of offspring, allowing them to rapidly invade populations even if they reduce the fitness of individuals carry...

Mother’s curse and indirect genetic effects: Do males matter to mitochondrial genome evolution?

Journal Article
Keaney, T. A., Wong, H. W. S., Dowling, D. K., Jones, T. M., & Holman, L. (2020)
Mother’s curse and indirect genetic effects: Do males matter to mitochondrial genome evolution?. Journal of Evolutionary Biology, 33(2), 189-201. https://doi.org/10.1111/jeb.13561
Maternal inheritance of mitochondrial DNA (mtDNA) was originally thought to prevent any response to selection on male phenotypic variation attributable to mtDNA, resulting in ...

Fitness consequences of the selfish supergene Segregation Distorter

Journal Article
Wong, H. W. S., & Holman, L. (2020)
Fitness consequences of the selfish supergene Segregation Distorter. Journal of Evolutionary Biology, 33(1), 89-100. https://doi.org/10.1111/jeb.13549
Segregation distorters are selfish genetic elements that subvert Mendelian inheritance, often by destroying gametes that do not carry the distorter. Simple theoretical models ...

Evolutionary simulations of Z-linked suppression gene drives

Journal Article
Holman, L. (2019)
Evolutionary simulations of Z-linked suppression gene drives. Proceedings of the Royal Society B: Biological Sciences, 286(1912), https://doi.org/10.1098/rspb.2019.1070
Synthetic gene drives may soon be used to suppress or eliminate populations of disease vectors, pathogens, invasive species, and agricultural pests. Recent proposals have focu...

Meta-analytic evidence that sexual selection improves population fitness

Journal Article
Cally, J. G., Stuart-Fox, D., & Holman, L. (2019)
Meta-analytic evidence that sexual selection improves population fitness. Nature Communications, 10, https://doi.org/10.1038/s41467-019-10074-7
Sexual selection has manifold ecological and evolutionary consequences, making its net effect on population fitness difficult to predict. A powerful empirical test is to exper...

Researchers collaborate with same-gendered colleagues more often than expected across the life sciences

Journal Article
Holman, L., & Morandin, C. (2019)
Researchers collaborate with same-gendered colleagues more often than expected across the life sciences. PLOS ONE, 14(4), https://doi.org/10.1371/journal.pone.0216128
Evidence suggests that women in academia are hindered by conscious and unconscious biases, and often feel excluded from formal and informal opportunities for research collabor...

Comparative transcriptomics of social insect queen pheromones

Journal Article
Holman, L., Helanterä, H., Trontti, K., & Mikheyev, A. S. (2019)
Comparative transcriptomics of social insect queen pheromones. Nature Communications, 10, https://doi.org/10.1038/s41467-019-09567-2
Queen pheromones are chemical signals that mediate reproductive division of labor in eusocial animals. Remarkably, queen pheromones are composed of identical or chemically sim...

Evolution of female choice under intralocus sexual conflict and genotype-by-environment interactions

Journal Article
Li, X., & Holman, L. (2018)
Evolution of female choice under intralocus sexual conflict and genotype-by-environment interactions. Philosophical Transactions B: Biological Sciences, 373(1757), 20170425. https://doi.org/10.1098/rstb.2017.0425
In many species, females are hypothesized to obtain ‘good genes’ for their offspring by mating with males in good condition. However, female preferences might deplete genetic ...

Onwards and upwards: a response to comments on Holman

Journal Article
Holman, L. (2018)
Onwards and upwards: a response to comments on Holman. Behavioral Ecology, 29(6), 1214-1215. https://doi.org/10.1093/beheco/ary094
Abstract not available.

Queen pheromones and reproductive division of labor: a meta-analysis

Journal Article
Holman, L. (2018)
Queen pheromones and reproductive division of labor: a meta-analysis. Behavioral Ecology, 29(6), 1199–1209. https://doi.org/10.1093/beheco/ary023
Our understanding of chemical communication between social insect queens and workers has advanced rapidly in recent years. Several studies have identified chemicals produced b...

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