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72 results

Efficacy of two Chlamydia abortus subcellular vaccines in a pregnant ewe challenge model for ovine enzootic abortion

Journal Article
Livingstone, M., Ranjan Wattegedera, S., Palarea-Albaladejo, J., Aitchison, K., Corbett, C., Sait, M., …Longbottom, D. (2021)
Efficacy of two Chlamydia abortus subcellular vaccines in a pregnant ewe challenge model for ovine enzootic abortion. Vaccines, 9(8), https://doi.org/10.3390/vaccines9080898
Chlamydia abortus, the aetiological agent of enzootic abortion of ewes, is a major cause of reproductive loss in small ruminants worldwide, accounting for significant economic...

Type 1 diabetes patients increase CXCR4+ and CXCR7+ haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated

Journal Article
Taylor, G. S., Shaw, A., Smith, K., Capper, T. E., Scragg, J. H., Cronin, M., …West, D. J. (2021)
Type 1 diabetes patients increase CXCR4+ and CXCR7+ haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated. Scientific Reports, 11, https://doi.org/10.1038/s41598-021-93886-2
Background: Exercise mobilizes angiogenic cells, which stimulate vascular repair. However, limited research suggests exercise-induced increase of endothelial progenitor cell (...

A paradigm shift to combat indoor respiratory infection

Journal Article
Morawska, L., Allen, J., Bahnfleth, W., Bluyssen, P. M., Boerstra, A., Buonanno, G., …Yao, M. (2021)
A paradigm shift to combat indoor respiratory infection. Science, 372(6543), 689-691. https://doi.org/10.1126/science.abg2025
There is great disparity in the way we think about and address different sources of environmental infection. Governments have for decades promulgated a large amount of legisla...

Can we do better? A guide to pandemics – some Dos and Don'ts for the next one

Journal Article
Tang, J. W., Kwok, K. O., Loh, T. P., Lee, C. K., Heraud, J., & Dancer, S. J. (2021)
Can we do better? A guide to pandemics – some Dos and Don'ts for the next one. Journal of Infection, 83(1), 119-145. https://doi.org/10.1016/j.jinf.2021.04.017
Specific features of any rapidly spread pathogen needs early recognition and assessment for possible pandemic potential. These include: inter-person transmissibility and expon...

How dirty is your QWERTY? The risk of healthcare pathogen transmission from computer keyboards

Journal Article
Ledwoch, K., Dancer, S., Otter, J., Kerr, K., Roposte, D., & Maillard, J. (2021)
How dirty is your QWERTY? The risk of healthcare pathogen transmission from computer keyboards. Journal of Hospital Infection, 112, 31-36. https://doi.org/10.1016/j.jhin.2021.02.021
Introduction Healthcare environmental surfaces may be contaminated with micro-organisms that cause healthcare-associated infections (HCAIs). Special attention is paid to near-...

Risk Factors for Leg Ulceration in People Who Inject Drugs: A Cross-Sectional Study

Journal Article
Coull, A. F., Kyle, R. G., Hanson, C. L., & Watterson, A. (2021)
Risk Factors for Leg Ulceration in People Who Inject Drugs: A Cross-Sectional Study. Journal of Clinical Nursing, 30(11-12), 1623-1632. https://doi.org/10.1111/jocn.15716
Aims and Objectives The aim of this study was to assess, for the first time in a hard-to-reach population, the risk factors for leg ulceration among PWID, with the objective o...

Putting a balance on the aerosolization debate around SARS-CoV-2

Journal Article
Dancer, S. J., Tang, J. W., Marr, L. C., Miller, S., Morawska, L., & Jimenez, J. L. (2020)
Putting a balance on the aerosolization debate around SARS-CoV-2. Journal of Hospital Infection, 105(3), 569-570. https://doi.org/10.1016/j.jhin.2020.05.014
No abstract available.

Bacterial Transfer To Fingertips During Sequential Surface Contacts With And Without Gloves

Journal Article
King, M., López‐García, M., Atedoghu, K. P., Zhang, N., Wilson, A. M., Weterings, M., …Fletcher, L. A. (2020)
Bacterial Transfer To Fingertips During Sequential Surface Contacts With And Without Gloves. Indoor Air, 30(5), 993-1004. https://doi.org/10.1111/ina.12682
Bacterial transmission from contaminated surfaces via hand contact plays a critical role in disease spread. However, the fomite‐to‐finger transfer efficiency of microorganisms...

Reducing hand recontamination of healthcare workers during COVID-19

Journal Article
Gon, G., Dancer, S., Dreibelbis, R., Graham, W. J., & Kilpatrick, C. (2020)
Reducing hand recontamination of healthcare workers during COVID-19. Infection Control and Hospital Epidemiology, 41(7), 870-871. https://doi.org/10.1017/ice.2020.111
No abstract available.

Dynamic Transmission of Staphylococcus Aureus in the Intensive Care Unit

Journal Article
Adams, C. E., & Dancer, S. J. (2020)
Dynamic Transmission of Staphylococcus Aureus in the Intensive Care Unit. International Journal of Environmental Research and Public Health, 17(6), https://doi.org/10.3390/ijerph17062109
Staphylococcus aureus is an important bacterial pathogen. This study utilized known staphylococcal epidemiology to track S. aureus between patients, surfaces, staff hands and ...
27 results

Does Residual Beta Cell Function and Exercise Offer Synergistic Protection Against Hyperglycaemic Induced Circulating Vasoprotective Dysfunction in Type 1 Diabetes?

2021 - 2022
For people with T1D, exercise is beneficial, potentially reducing the progression of diabetes-related complications. Many people (up to 80%) with T1D still release small amounts of insulin together wi...
Funder: Diabetes Research & Wellness Foundation

TB/COVID-19 co-infections within a 3D in vitro imaging system

2021 - 2022
TB/COVID-19 co-infections within a 3D in vitro imaging system
Funder: Animal Free Research UK | Value: £500

Developing an adoptive regulatory T cell therapy for the treatment of rheumatoid arthritis

2021 - 2023
The immune system contains a balance of cells that turn responses ‘on’ and those that turn it ‘off’. When this balance breaks down, inappropriate immune responses can attack healthy tissue...
Funder: Chief Scientists Office | Value: £229,020

Prevalence of Brucellosis and Q-fever in livestock within the Ashanti region of Ghana

2020 - 2022
To determine the seroprevalence of abortifacient zoonoses (Brucellosis and Coxiellosis) in small ruminants within the Ashanti region of Ghana
Funder: Microbiology Society | Value: £2,530

Host Defence Peptides as novel modulators of autophagy in Inflammatory Bowel Disease

2019 - 2022
Increasing numbers of patients are diagnosed with inflammatory bowel disease (IBD) each year, both in the United Kingdom and worldwide. Most drugs in current use for the treatment of IBD target the im...
Funder: The Daphne Jackson Trust | Value: £83,167

EEID travel award: Understanding transmission dynamics for bacterial zoonoses in humans, goats and camels among pastoral communities in Northern Kenya

2019 - 2019
EEID travel award: Understanding transmission dynamics for bacterial zoonoses in humans, goats and camels among pastoral communities in Northern Kenya
Funder: Biotechnology and Biological Sciences Research Council | Value: £1,960

Cathelicidins as Novel Therapeutic Antivirals for Dengue Infection

2019 - 2022
A significant challenge faced by modern society is the lack of therapeutics for a large number of infections, particularly those that are endemic or widely spread in developing countries. Dengue is on...
Funder: Medical Research Council | Value: £269,873

The influence of aerobic exercise training to attenuate chemotherapy-induced cardiotoxicity and vascular dysfunction in breast cancer and leukaemia patients

2018 - 2021
This project will be based in the Sport, Exercise and Health Research theme within the School of Applied Sciences, and is led by Dr. Mark Ross, Miss Karen Campbell and Professor Geraint Florida-James ...
Funder: ENU Development Trust | Value: £58,079

Bacteriophage endolysins and novel lipid-degrading proteins as a treatment for Rhodococcus equi infections in foals

2018 - 2019
Rhodococcus equi (Req) is responsible for severe respiratory disease of foals with a major economic impact on the equine industry, and can be endemic on stud farms. In foals under 6 months of age, thi...
Funder: Horserace Betting Levy Board | Value: £10,832

Rutherford fund Strategic Partner Grant

2018 - 2019
Rutherford Fellows, will work in project areas related to food safety (Pathogen detection, AMR etc) and food spoilage. Rutherford Fund, are funded by BEIS and the scheme is being managed by Universit...
Funder: Department for Business, Energy & Industrial Strategy | Value: £39,800