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52 results

Psychological interventions for ICD-11 Complex PTSD symptoms: Systematic review and meta-analysis

Journal Article
Karatzias, T., Murphy, P., Cloitre, M., Bisson, J., Roberts, N., Shevlin, M., …Hutton, P. (2019)
Psychological interventions for ICD-11 Complex PTSD symptoms: Systematic review and meta-analysis. Psychological Medicine, 49(11), 1761-1775. https://doi.org/10.1017/S0033291719000436
Background: The 11th revision to the WHO International Classification of Diseases (ICD-11) identified Complex Posttraumatic Stress Disorder (CPTSD) as a new condition. There i...

Cognitive behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT

Journal Article
Morrison, A. P., Pyle, M., Gumley, A., Schwannauer, M., Turkington, D., MacLennan, G., …Kingdon, D. (2019)
Cognitive behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT. Health Technology Assessment, 23(7), 1-144. https://doi.org/10.3310/hta23070
Background: Clozapine (clozaril, Mylan Products Ltd) is a first-choice treatment for people withschizophrenia who have a poor response to standard antipsychotic medication. Ho...

A feasibility study of a cross-diagnostic, CBT-based psychological intervention for acute mental health inpatients: Results, challenges, and methodological implications

Journal Article
Paterson, C., Karatzias, T., Harper, S., Dougall, N., Dickson, A., & Hutton, P. (2019)
A feasibility study of a cross-diagnostic, CBT-based psychological intervention for acute mental health inpatients: Results, challenges, and methodological implications. British Journal of Clinical Psychology, 58(2), 211-230. https://doi.org/10.1111/bjc.12209
Objectives Acute psychiatric inpatient wards are characterised by minimal provision of therapeutic activities and high readmission rates. Implementation of a comprehensive inp...

Suicidal ideation in people with psychosis not taking antipsychotic medication: Do negative appraisals and negative metacognitive beliefs mediate the effect of symptoms?

Journal Article
Hutton, P., Di Rienzo, F., Turkington, D., Spencer, H., & Taylor, P. (2019)
Suicidal ideation in people with psychosis not taking antipsychotic medication: Do negative appraisals and negative metacognitive beliefs mediate the effect of symptoms?. Schizophrenia Bulletin, 45(1), 37-47. https://doi.org/10.1093/schbul/sby153
Between 5 and 10 percent of people with psychosis will die by suicide, a rate which is 20 to 75 times higher than the general population. This risk is even greater in those no...

The paranoia as defence model of persecutory delusions: a systematic review and meta-analysis

Journal Article
Murphy, P., Bentall, R. P., Freeman, D., O'Rourke, S., & Hutton, P. (2018)
The paranoia as defence model of persecutory delusions: a systematic review and meta-analysis. Lancet Psychiatry, 5(11), 913-929. https://doi.org/10.1016/S2215-0366%2818%2930339-0
Background An influential psychological model of persecutory delusions proposed they are caused by a bias towards holding others responsible for negative events, which serves ...

The effect of reducing the 'jumping to conclusions' bias on treatment decision-making capacity in psychosis: A randomised controlled trial with mediation analysis

Journal Article
Turner, D. T., MacBeth, A., Larkin, A., Moritz, S., Livingstone, K., Campbell, A., & Hutton, P. (2019)
The effect of reducing the 'jumping to conclusions' bias on treatment decision-making capacity in psychosis: A randomised controlled trial with mediation analysis. Schizophrenia Bulletin, 45(4), 784-793. https://doi.org/10.1093/schbul/sby136
Background Evidence-based psychological interventions to support treatment decision-making capacity (‘capacity’) in psychosis do not currently exist. This study sought to esta...

Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks

Journal Article
Woodrow, A., Sparks, S., Bobrovskaia, V., Paterson, C., Murphy, P., & Hutton, P. (2019)
Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks. Psychological Medicine, 49(1), 32-48. https://doi.org/10.1017/S0033291718002660
To identify factors which may help or hinder decision-making ability in people with psychosis, we did a systematic review and meta-analysis of their performance on the Iowa an...

A systematic review and meta-analysis of group treatments for adults with symptoms associated with complex post-traumatic stress disorder

Journal Article
Mahoney, A., Karatzias, T., & Hutton, P. (2018)
A systematic review and meta-analysis of group treatments for adults with symptoms associated with complex post-traumatic stress disorder. Journal of Affective Disorders, doi:10.1016/j.jad.2018.09.059
Background: No previous meta-analyses have specifically investigated the effectiveness of psychological group therapy for symptoms associated with complex interpersonal trauma...

Cognitive Behavioral Therapy for antipsychotic-free schizophrenia spectrum disorders: Does therapy dose influence outcome?

Journal Article
Spencer, H. M., McMenamin, M., Emsley, R., Turkington, D., Dunn, G., Morrison, A. P., …Dudley, R. (2018)
Cognitive Behavioral Therapy for antipsychotic-free schizophrenia spectrum disorders: Does therapy dose influence outcome?. Schizophrenia Research, 202, 385-386. https://doi.org/10.1016/j.schres.2018.07.016
This study investigated the effect of “dose” and the components of Cognitive Behavioral Therapy (CBT) on treatment effects. It is a secondary analysis of the ACTION (Assessmen...

Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial

Journal Article
Morrison, A. P., Pyle, M., Gumley, A., Schwannauer, M., Turkington, D., MacLennan, G., …Tully, S. (2018)
Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial. Lancet Psychiatry, 5(8), 633-643. https://doi.org/10.1016/s2215-0366%2818%2930184-6
Background Although clozapine is the treatment of choice for treatment-refractory schizophrenia, 30–40% of patients have an insufficient response, and others are unable to tol...
8 results

Standardisation and validation of the International Trauma Interview (ITI)

2020 - date
Zoe Wagland | Director of Studies: Prof Thanos Karatzias | Second Supervisor: Dr Paul Hutton

Developing a Meaningful Framework for Change to Improve Mental Health and Wellbeing for Police Officers

2019 - date
Thomas Peyton-Lander | Director of Studies: Dr Jennifer Murray | Second Supervisor: Nadine Dougall

Implicit self-esteem in paranoia and persecutory delusions

2018 - date
Georgina Davis | Director of Studies: Dr Paul Hutton | Second Supervisor: Prof Thanos Karatzias

Emotion regulation in psychosis

2016 - date
Amanda Woodrow | Director of Studies: Dr Paul Hutton | Second Supervisor: Prof Thanos Karatzias

Mindfulness-based interventions for people with recent-onset psychosis: A randomized controlled trial in Hong Kong

2016 - date
Annie Yip | Director of Studies: Prof Thanos Karatzias | Second Supervisor: Dr Mick Fleming

A meta-analysis and controlled evaluation of short term pyschological intervention for acute mental health inpatients

2014 - 2018
There is evidence to suggest that psychological therapies for severe mental health ...
Charlotte Paterson | Director of Studies: Prof Thanos Karatzias | Second Supervisor: Dr Paul Hutton

Exploring mutual care between people with intellectual disabilities and their family carers in Scotland

2014 - date
Gillian Thompson | Director of Studies: Dr Paul Hutton | Second Supervisor: Michael Brown

The effectiveness of a stage-1 psychoeducational intervention versus waiting list to stabilise complex interpersonal trauma symptomatology in female offenders

2013 - 2019
Adam Mahoney | Director of Studies: Prof Thanos Karatzias | Second Supervisor: Dr Paul Hutton

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