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82 results

The relationship between ICD-11 PTSD, complex PTSD and dissociative experiences

Journal Article
Hyland, P., Shevlin, M., Fyvie, C., Cloitre, M., & Karatzias, T. (2020)
The relationship between ICD-11 PTSD, complex PTSD and dissociative experiences. Journal of Trauma and Dissociation, 21(1), 62-72. https://doi.org/10.1080/15299732.2019.1675113
Debate exists in the trauma literature regarding the role of dissociation in traumatic stress disorders. With the release of the new ICD-11 diagnostic guideline for posttrauma...

Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis

Journal Article
Staines, K., Ikpegbu, E., Törnqvist, A., Dillon, S., Javaheri, B., Amin, A. K., …Farquharson, C. (2019)
Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis. BMC Musculoskeletal Disorders, 20, https://doi.org/10.1186/s12891-019-2731-9
Background: Subchondral bone (SCB) thickening is one of the earliest detectable changes in osteoarthritic joints and is considered a potential trigger for subsequent articular...

Differentiating Symptom Profiles of ICD-11 PTSD, Complex PTSD and Borderline Personality Disorder: A Latent Class Analysis in a Multiply Traumatised Sample

Journal Article
Jowett, S., Karatzias, T., Shevlin, M., & Albert, I. (2020)
Differentiating Symptom Profiles of ICD-11 PTSD, Complex PTSD and Borderline Personality Disorder: A Latent Class Analysis in a Multiply Traumatised Sample. Personality Disorders: Theory, Research, and Treatment, 11(1), 36-45. https://doi.org/10.1037/per0000346
Background: Complex PTSD (CPTSD) has been included as a diagnostic category in the ICD-11 consisting of six symptom clusters; the three PTSD criteria of Re-experiencing, Avoid...

The inflammatory bowel disease drug azathioprine induces autophagy via mTORC1 and the unfolded protein response sensor PERK

Journal Article
Hooper, K. M., Casanova, V., Kemp, S., Staines, K. A., Satsangi, J., Barlow, P. G., …Stevens, C. (2019)
The inflammatory bowel disease drug azathioprine induces autophagy via mTORC1 and the unfolded protein response sensor PERK. Inflammatory Bowel Diseases, 25(9), 1481-1496. https://doi.org/10.1093/ibd/izz039
Background Genetic studies have strongly linked autophagy to Crohn's disease (CD) and stimulating autophagy in CD patients may be therapeutically beneficial. The aim of this s...

Using Foucauldian Discourse Analysis to Analyze Young Women’s Constructions of the Human Papillomavirus Vaccine

Journal Article
Gray Brunton, C., Todorova, I., Petrova, D., Carnegie, E., & Whittaker, A. (2018)
Using Foucauldian Discourse Analysis to Analyze Young Women’s Constructions of the Human Papillomavirus Vaccine. Sage Research Methods Cases, https://doi.org/10.4135/9781526440235
This case study introduces the reader to Foucauldian discourse analysis (FDA) as applied to a cross-cultural project around young women’s constructions of the Human Papillomav...

Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease

Journal Article
Hooper, K. M., Barlow, P. G., Henderson, P., & Stevens, C. (2019)
Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease. Inflammatory Bowel Diseases, 25(4), 661-671. https://doi.org/10.1093/ibd/izy380
Inflammatory Bowel Disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis, is characterised by chronic inflammation of the gastrointestinal tract. Aetiology...

An evaluation of mainstream type 2 diabetes educational programmes in relation to the needs of people with intellectual disabilities: A systematic review of the literature

Journal Article
Brown, M. J., Maine, A., Brown, M. .., Dickson, A., & Truesdale, M. (2018)
An evaluation of mainstream type 2 diabetes educational programmes in relation to the needs of people with intellectual disabilities: A systematic review of the literature. Journal of Applied Research in Intellectual Disabilities, 32(2), 256-279. https://doi.org/10.1111/jar.12544
Background Risk reduction and self‐management programs for type 2 diabetes (T2D) are commonplace. However, little is known about their appropriateness for people with intellec...

Holistic needs assessment in brain cancer patients: A systematic review of available tools

Journal Article
Afseth, J., Neubeck, L., Karatzias, T., & Grant, R. (2019)
Holistic needs assessment in brain cancer patients: A systematic review of available tools. European Journal of Cancer Care, 28(3), https://doi.org/10.1111/ecc.12931
This systematic review describes tools which could be considered for use for holistic needs assessment in Brain Cancer. MEDLINE, Cumulative Index to Nursing and Allied Health ...

Colorectal Cancer in People with Intellectual Disabilities

Journal Article
Willis, D., Samalin, E., & Satgé, D. (2018)
Colorectal Cancer in People with Intellectual Disabilities. Oncology, 95(6), 323-336. https://doi.org/10.1159/000492077
People with intellectual disabilities (PWIDs) are now living longer; thus, the incidence of cancer within this population is increasing. Available data indicate an excess of d...

The challenges of type 1 diabetes and new psychoactive substance misuse

Journal Article
Charlton, J., Albanese, A., & Brodie, L. (2018)
The challenges of type 1 diabetes and new psychoactive substance misuse. Practical Diabetes, 35(3), 81-85a. https://doi.org/10.1002/pdi.2168
Substance misuse, specifically novel psychoactive substances (NPSs), can have multiple effects on physical and psychological health and well-being. This is of particular conce...