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In situ characterization of nanoscale strains in loaded whole joints via synchrotron X-ray tomography

Journal Article
Madi, K., Staines, K., Bay, B., Javaheri, B., Geng, H., Bodey, A., …Lee, P. (2020)
In situ characterization of nanoscale strains in loaded whole joints via synchrotron X-ray tomography. Nature Biomedical Engineering, 4(3), 343-354. https://doi.org/10.1038/s41551-019-0477-1
Imaging techniques for quantifying changes in the hierarchical structure of deforming joints are constrained by destructive sample treatments, sample-size restrictions and len...

Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential

Journal Article
Sharma, A., Goring, A., Staines, K., Emery, R., Pitsillides, A. A., Oreffo, R. O., …Clarkin, C. E. (2020)
Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential. Matrix Biology Plus, 5(February 2020), https://doi.org/10.1016/j.mbplus.2019.100018
Mineralization of bone is achieved by the sequential maturation of the immature amorphous calcium phase to mature hydroxyapatite and is central to the process of bone developm...

Dementia in the workplace: are employers supporting employees living with dementia?

Journal Article
Egdell, V., Cook, M., Stavert, J., Ritchie, L., Tolson, D., & Danson, M. (in press)
Dementia in the workplace: are employers supporting employees living with dementia?. Aging & mental health, https://doi.org/10.1080/13607863.2019.1667299
Objectives As working lives extend and there is better recognition of early-onset dementias, employers need to consider dementia as a workplace concern. With suitable support,...

The effectiveness of home versus community-based weight control programmes initiated soon after breast cancer diagnosis: a randomised controlled trial

Journal Article
Harvie, M., Pegington, M., McMullan, D., Bundred, N., Livingstone, K., Campbell, A., …Howell, A. (2019)
The effectiveness of home versus community-based weight control programmes initiated soon after breast cancer diagnosis: a randomised controlled trial. British Journal of Cancer, https://doi.org/10.1038/s41416-019-0522-6
Background Breast cancer diagnosis may be a teachable moment for lifestyle behaviour change and to prevent adjuvant therapy associated weight gain. We assessed the acceptabili...

Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis

Journal Article
Staines, K., Ikpegbu, E., Törnqvist, A., Dillon, S., Javaheri, B., Amin, A. K., …Farquharson, C. (2019)
Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis. BMC Musculoskeletal Disorders, 20, https://doi.org/10.1186/s12891-019-2731-9
Background: Subchondral bone (SCB) thickening is one of the earliest detectable changes in osteoarthritic joints and is considered a potential trigger for subsequent articular...

How to build a bone: PHOSPHO1, biomineralization and beyond

Journal Article
Dillon, S., Staines, K. A., Millán, J. L., & Farquharson, C. (2019)
How to build a bone: PHOSPHO1, biomineralization and beyond. Journal of Bone and Mineral Research Plus, 3(7), https://doi.org/10.1002/jbm4.10202
Since its characterization two decades ago, the phosphatase PHOSPHO1 has been the subject of an increasing focus of research. This work has elucidated PHOSPHO1’s central role ...

Is the Zero-Wait Policy Always Optimum for Information Freshness (Peak Age) or Throughput?

Journal Article
Barakat, B., Keates, S., Wassell, I., & Arshad, K. (2019)
Is the Zero-Wait Policy Always Optimum for Information Freshness (Peak Age) or Throughput?. IEEE Communications Letters, 23(6), 987-990. https://doi.org/10.1109/LCOMM.2019.2907935
The Zero-Wait (ZW) policy is widely held to achieve maximum information 'freshness', i.e., to achieve minimum Peak Age (PA) and maximum throughput, for real-time Internet-of-T...

The effect of exporting hospitality and tourism degrees overseas on the home campus: a conceptual model.

Journal Article
Lagiewski, R. M., Barron, P., & Leask, A. (2019)
The effect of exporting hospitality and tourism degrees overseas on the home campus: a conceptual model. Journal of hospitality, leisure, sport & tourism education, 24, 211-222. https://doi.org/10.1016/j.jhlste.2019.03.005
Hospitality and tourism programmes have, over the recent decades, been involved in the delivery of their degrees in international locations through a variety of export models....

Employer Policy and Practice Toward Older Workers in Hong Kong: The Role of Shifting Intergenerational Dynamics

Journal Article
Egdell, V., Fuertes, V., Tjandra, N. C., & Chen, T. (2019)
Employer Policy and Practice Toward Older Workers in Hong Kong: The Role of Shifting Intergenerational Dynamics. Journal of Aging and Social Policy, 31(5), 445-466. https://doi.org/10.1080/08959420.2018.1563472
Many governments are seeking to encourage the extension of working lives to counteract potential labor market shortages that might result from population aging. Nevertheless, ...

Celebrating 70 years of Nursing and Midwifery in our National Health Service (NHS) Scotland

Report
Harper-McDonald, B., Taylor, G., & O'Connor, S. (2019)
Celebrating 70 years of Nursing and Midwifery in our National Health Service (NHS) Scotland. Edinburgh Napier University
No abstract available.
7 results

Care Home Data Platform

2019 - 2019
Care home research to develope a data and innovation platform to support inclusive, person-centred research in care homes in Lothian
Funder: NHS Lothian | Value: £28,882

Osteoarthritis: Going back to basics

2018 - 2021
Osteoarthritis (OA) is the most important ageing-related musculoskeletal disease, affecting almost 9 million people in the UK. Despite this, there remain many unanswered questions in our understanding...
Funder: Medical Research Council | Value: £351,321

Development of a novel 3D culture system to understand bone:cartilage crosstalk in osteoarthritis

2018 - 2022
Osteoarthritis affects more than 9 million people in the UK and is the leading cause of disability. In osteoarthritis, joint tissues (cartilage and bone) undergo structural damage which ultimately pro...
Funder: Medical Research Scotland | Value: £128,430

Imaging dynamics in biophysical/biochemical processes across the hierarchical scales (BioPro Network)

2018 - 2022
The ImagingBioPro network seeks to develop new, high energy imaging methods to capture the dynamic biochemical and biophysical processes in biological samples. The human body is highly structured – f...
Funder: Biotechnology and Biological Sciences Research Council | Value: £1,500

Investigating new therapies for osteoarthritis: a collaboration between ENU and Guangzhou Medical University, China

2018 - 2020
Investigating new therapies for osteoarthritis: a collaboration between ENU and Guangzhou Medical University, China Osteoarthritis is the most important ageing-related disease, estimated to affect 13...
Funder: ENU Development Trust | Value: £30,000

Physical ACTivity: the tool to improve the quality of LIFE in osteoporosis people

2018 - 2020
ACTLIFE is focused on the development and dissemination across Europe of ACTLIFE protocol aimed to the secondary and tertiary prevention of osteoporosis consequences through physical activities. In pa...
Funder: European Commission | Value: £1,236

Senior Visitors to Visitor Attractions

2017 - 2018
This project aims to develop a new and innovative structured visit programme focused on the needs and wants of this increasingly significant older population group. Specifically aimed at the over 75 y...
Funder: Edinburgh Innovations Ltd | Value: £9,972

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