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22 results

De novo design of novel protease inhibitor candidates in the treatment of SARS-CoV-2 using deep learning, docking, and molecular dynamic simulations

Journal Article
Arshia, A. H., Shadravan, S., Solhjoo, A., Sakhteman, A., & Sami, A. (2021)
De novo design of novel protease inhibitor candidates in the treatment of SARS-CoV-2 using deep learning, docking, and molecular dynamic simulations. Computers in Biology and Medicine, 139, Article 104967. https://doi.org/10.1016/j.compbiomed.2021.104967
The main protease of SARS-CoV-2 is a critical target for the design and development of antiviral drugs. 2.5 M compounds were used in this study to train an LSTM generative net...

Hardware Design for Autonomous Robot Evolution

Conference Proceeding
Hale, M. F., Angus, M., Buchanan, E., Li, W., Woolley, R., Le Goff, L. K., …Tyrrell, A. M. (2020)
Hardware Design for Autonomous Robot Evolution. In 2020 IEEE Symposium Series on Computational Intelligence (SSCI) (2140-2147). https://doi.org/10.1109/SSCI47803.2020.9308204
The long term goal of the Autonomous Robot Evolution (ARE) project is to create populations of physical robots, in which both the controllers and body plans are evolved. The t...

The effectiveness of cognitive-behavioural interventions at increasing adherence to physical activity in mental health populations: a systematic review

Journal Article
Snowden, A., Peddie, N., & Westbury, T. (2021)
The effectiveness of cognitive-behavioural interventions at increasing adherence to physical activity in mental health populations: a systematic review. Advances in Mental Health, 19(1), 94-112. https://doi.org/10.1080/18387357.2019.1684829
Objective: There is growing global evidence for stark inequalities in the physical health status and life-expectancy of people with a mental health diagnosis. In most cases, p...

Health professionals' lack of knowledge of central venous access devices: the impact on patients

Journal Article
Kelly, L. J., Snowden, A., Paterson, R., & Campbell, K. (2019)
Health professionals' lack of knowledge of central venous access devices: the impact on patients. British Journal of Nursing, 28(14), https://doi.org/10.12968/bjon.2019.28.14.S4
Background The literature on patient experience of living with a central venous access device (CVAD) is growing, but remains sparse. It suggests that patients accept CVADs as...

A review of the impact of utilising electronic medical records for clinical research recruitment

Journal Article
Lai, Y. S., & Afseth, J. D. (2019)
A review of the impact of utilising electronic medical records for clinical research recruitment. Clinical Trials, 16(2), 194-203. https://doi.org/10.1177/1740774519829709
Introduction: Recruitment is an important aspect of clinical research, as poor recruitment could undermine the scientific value of a trial or delay the development process of ...

Best supportive care in advanced lung cancer—more than a label?

Journal Article
Bowden, J., Fenning, S., Marron, B., Macpherson, C., Boyce, S., Wardrope, V., …Johnston, L. (2018)
Best supportive care in advanced lung cancer—more than a label?. BMJ, 363, k5017. https://doi.org/10.1136/bmj.k5017
We should be accountable for delivering the right care in the right place for people nearing the end of life, say Jo Bowden and colleagues.

Holistic needs assessment in brain cancer patients: A systematic review of available tools

Journal Article
Afseth, J., Neubeck, L., Karatzias, T., & Grant, R. (2019)
Holistic needs assessment in brain cancer patients: A systematic review of available tools. European Journal of Cancer Care, 28(3), https://doi.org/10.1111/ecc.12931
This systematic review describes tools which could be considered for use for holistic needs assessment in Brain Cancer. MEDLINE, Cumulative Index to Nursing and Allied Health ...

Proactive community support tailored to holistic needs: A cohort study

Journal Article
Snowden, A., Young, J., & Savinc, J. (2018)
Proactive community support tailored to holistic needs: A cohort study. Cancer Medicine, 7(9), 4836-4845. https://doi.org/10.1002/cam4.1709
Background: It is increasingly internationally recognised that a cancer diagnosis impacts on people practically and financially as well as physically and psychologically. It ...

Exploring male identity in non-professional carers of someone with cancer: preliminary analysis

Presentation / Conference
Young, J., Snowden, A., Stenhouse, R., & Kyle, R. (2018, March)
Exploring male identity in non-professional carers of someone with cancer: preliminary analysis. Poster presented at British Psych-Oncology Society Annual Conference
Background Across the world the majority of home‐based care for ill family members is carried out by women. Consequently, research in this field has predominately focused on ...

The role of social context in symptom appraisal and help-seeking among people with lung or colorectal symptoms: A qualitative interview study

Journal Article
Dobson, C., Russell, A., Brown, S., & Rubin, G. (2018)
The role of social context in symptom appraisal and help-seeking among people with lung or colorectal symptoms: A qualitative interview study. European Journal of Cancer Care, 27(2), https://doi.org/10.1111/ecc.12815
Prolonged diagnostic intervals are associated with poorer outcomes, and the patient interval appears to be a substantial contributor to the overall length of the diagnostic in...
10 results

Transforming Cancer Care Evaluation

2022 - 2024
This is a follow on Evaluation from the TCAT and the ICJ that Edinburgh Napier undertook.
Funder: MacMillan Cancer Support | Value: £79,225

Explore the perception of nurses about potential occupational exposure to cytotoxic drugs

2022 - 2024
Delivering cancer treatment to patients either in hospital or at home requires health and safety regulation because the drug is classed as toxic to body cells and when exposed to the treatment it can...
Funder: The UK Oncology Nursing Society | Value: £48,348

Development of an on-line platform for cancer and cancer screening information

2021 - 2022
Due to the pandemic, information and awareness about conditions such as cancer and cancer screening, which is usually delivered face-to-face, has ceased. We plan to undertake a feasibility study to d...
Funder: Scottish Government | Value: £10,000

Slowing the flow of zero day admissions to hospital: data linkage to inform intervention prioritisation along paediatric referral pathways

2019 - 2021
The number of children admitted to Scottish hospitals continues to rise, and this is due to cases admitted and discharged on the same day (“zero day admissions”). We do not currently know how best to ...
Funder: Chief Scientists Office | Value: £19,237

The influence of aerobic exercise training to attenuate chemotherapy-induced cardiotoxicity and vascular dysfunction in breast cancer and leukaemia patients

2018 - 2021
This project will be based in the Sport, Exercise and Health Research theme within the School of Applied Sciences, and is led by Dr. Mark Ross, Miss Karen Campbell and Professor Geraint Florida-James ...
Funder: ENU Development Trust | Value: £58,079

A brief school-based intervention to reduce sunburn in adolescence: A feasibility study

2018 - 2018
Lay summary: The sun can be harmful. If children/adolescents get sunburnt five or more times, they are twice as likely to get skin cancer as an adult. The sun can be beneficial. It is a source of vita...
Funder: Chief Scientists Office | Value: £1,273

Improving early detection of melanoma by increasing young people’s awareness of symptoms, skin self-examination and communication: A quasi-experimental trial with embedded process evaluation

2016 - 2017
Aims To adapt our existing brief school-based psycho-educational cancer awareness intervention to focus exclusively on increasing early detection of melanoma among young people (14-15 years) and test ...
Funder: Melanoma Focus

Career trajectories of Nurses in Scotland 2001-2011

2015 - 2016
Background Evidence-informed recruitment and retention strategies are required to ensure the nursing workforce has sufficient capacity and capability to deliver care to Scotland’s population. Current ...
Funder: Scottish Government | Value: £5,000

Development of a patient Concern Inventory in Brain Cancer Patients for outpatient consultation

2013 - 2015
This research project will undertake focus groups with glioma patients to explore the concerns they would like to discuss in outpatient neuro-oncology medical consultations. It will aim to identify co...
Funder: Edinburgh & Lothians Health Foundation | Value: £9,428

Is the patient dying? Ensuring safe, effective and person-centred care

2013 - 2016
Two year research and development project to investigate and develop reliable systems and processes for patient flow and care management. This will be investigated within the Scottish patient safety P...
Funder: Edinburgh & Lothians Health Foundation | Value: £58,059

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