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23 results

Nanoparticles - a potential danger to male reproductive health? Development of in vitro testes model.

Presentation / Conference
Fulton, N., Malone, E., O’Neil, M., & Hutchison, G. (2010, June)
Nanoparticles - a potential danger to male reproductive health? Development of in vitro testes model. Poster presented at Nanotoxicology 2010, Edinburgh
Nanoparticles (NP) are sized between 1 and 100 nanometers and are currently the subject of significant research due to their important role in the biomedical, materials and co...

Immunomodulatory effects of cannabinoids in human T-lymphocytes

Conference Proceeding
Schinwald, A., Galban-Horcajo, F., Malone, E., & Smith, P. (2009)
Immunomodulatory effects of cannabinoids in human T-lymphocytes. In Proceedings of the British Pharmacological Society
Background: Circulating levels of endocannabinoids are elevated in obese and hyperglycaemic patients and may contribute to immune dysfunction in obesity and diabetes. Cannabin...

Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo.

Journal Article
Taylor, M. D., LeGoff, L., Harris, A., Malone, E. M., Allen, J. E. & Maizels, R. M. (2005)
Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. Journal of Immunology. 174, 4924 – 4933. ISSN 0022-1767
Human filarial parasites cause chronic infection associated with long-term down-regulation of the host’s immune response. We show here that CD4+ T cell regulation is the main ...
11 results

Bio-Nanomaterial Hazard Assessment: development of in vitro models to aid assessment of reproductive function in response to nanomedicines

2019 - date
Sarah Horgan | Director of Studies: Prof Gary Hutchison | Second Supervisor: Dr Eva Malone

Performance in enduro mountain biking: the influence of training status, recovery and vibration

2016 - 2019
This PhD project is to investigate the physiological demands of elite enduro mountain bike racing. Previ...
Dr Lewis Kirkwood | Director of Studies: Prof Geraint Florida-James | Second Supervisor: Dr Eva Malone

Design, synthesis and biological evaluation of novel targeted anthelmintic agents

2015 - 2020
Aiman Rehan | Director of Studies: Dr David Mincher | Second Supervisor: Agnes Turnbull

The development of a caenorhabtitis elegans model for the assessment of toxicity: application in the treatment of parasitic worm infections

2013 - 2017
Eyitayo Oluwadare | Director of Studies: Dr Lorna Proudfoot | Second Supervisor: Dr Eva Malone

Assessing toxicity of engineered nanomaterials in the male reproductive system: Developing an improved testing strategy for hazard assessment

2011 - 2019
"There is a paucity of knowledge relating to the effects of...
Bryony Ross | Director of Studies: Prof Gary Hutchison | Second Supervisor: Dr Eva Malone

The influence of age, aerobic fitness, cardiovascular risk factors and cytomegalovirus on angiogenic T cells and endothelial progenitor cells

2011 - 2016
Dr Mark Ross | Director of Studies: Prof Geraint Florida-James | Second Supervisor: Dr Eva Malone

Caenorhabditis elegans as a model for the assessment of nanomaterial toxicity

2011 - 2013
Louise Nicol | Director of Studies: Dr Lorna Proudfoot | Second Supervisor: Dr Eva Malone

The effect of diurnal phase on performance physiology and immune system

2010 - 2017
Dr Peter Tormey | Director of Studies: Prof Geraint Florida-James | Second Supervisor: Mark Fogarty

Diurnal variation: effect on immune function and athletic performance in elite middle distance runners

2009 - 2015
Purpose: To investigate the physiological, immunological and psychological response to an intense ...
Boukhemiss Boukelia | Director of Studies: Prof Geraint Florida-James

Sleep disruption, immune cell redeployment and endocrine response following an acute bout of exercise

2007 - 2016
Dr Lesley Ingram-Sills | Director of Studies: Prof Geraint Florida-James | Second Supervisor: Dr Eva Malone

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