Ross, M. D. (2016). The Influence of Age, Cardiorespiratory Fitness, Exercise and Sedentary Behaviours on Circulating Angiogenic Cells and Cell Surface Receptor Expression. (Thesis)
Cardiovascular disease (CVD) is the biggest killer of people in western civilisation. Age is a significant risk factor for the development for CVD, and treatments and therapie...
Ross, M. (2017, June). Ageing, exercise and circulating angiogenic T-cells and vasculogenic progenitors. Paper presented at Edinburgh Immunology Group Symposium, University of Edinburgh
Ross, M., Malone, E., Simpson, R., & Florida-James., G. (2015, May). The Influence of Age, and Cardiorespiratory Fitness on Circulating Angiogenic T Cells and CXCR4 expression. Poster presented at American College of Sports Medicine (ACSM) Annual Congress, Boston
Aging is associated with endothelial dysfunction, reduced angiogenic capabilities, and an increase in arterial stiffness. Regular exercise is known to offset the age-related d...
ENU Development Trust
This project will be based in the Sport, Exercise and Health Research theme within the School of Applied Sciences, and is led by Dr. Mark Ross, Miss Karen Campbell and Professor Geraint Florida-James ...
Scottish Funding Council
Ranking novel immune-modulating therapeutics for progression to clinical development
Carnegie Trust for the Universities of Scotland
The project aims to ascertain pollution exposure on Edinburgh main roads and greener routes, and also determine the health effects of active commuting via these routes
Smith, K., Muggeridge, D. J., Easton, C., & Ross, M. D. (in press). An acute dose of inorganic dietary nitrate does not improve high-intensity, intermittent exercise performance in temperate or hot and humid conditions. European Journal of Applied Physiology, doi:10.1007/s00421-018-04063-9
Purpose: Dietary nitrate (NO3-) has repeatedly been shown to improve endurance and intermittent, high-intensity events in temperate conditions. However, the ergogenic effects...
O'Carroll, L., Wardrop, B., Murphy, R. P., Ross, M. D., & Harrison, M. (in press). Circulating angiogenic cell response to sprint interval and continuous exercise. European Journal of Applied Physiology,
Although commonly understood as immune cells, certain T lymphocyte and monocyte subsets have angiogenic potential, contributing to blood vessel growth and repair. These cells ...
Ross, M. D. (2018). Endothelial Regenerative Capacity and Aging: Influence of Diet, Exercise and Obesity. Current Cardiology Reviews, 14(4), 233-244. doi:10.2174/1573403X14666180726112303
The endothelium plays an important role in cardiovascular regulation, from blood flow, to platelet aggregation, immune cell infiltration and demargination. A dysfunctional end...
angiogenic T cells compared with younger men. Physiological Reports, 6(12), e13697. doi:10.14814/phy2.13697
Aging is associated with elevated cardiovascular disease risk. As a result of aging, endothelial dysfunction develops, partly due to a reduction in vascular regenerative abili...
Kemp, S., Young, L., Ross, M., Prach, M., Hutchison, G. R., Malone, E., & Fraser, J. A. (2018). Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations. Scientific Reports, 8(1), doi:10.1038/s41598-018-25854-2. ISSN 2045-2322
Neutrophil surveillance is central to nanoparticle clearance. Silver nanoparticles (AgNP) have numerous uses, however conflicting evidence exists as to their impact on neutrop...
Ross, M. D., Malone, E. M., Simpson, R., Cranston, I., Ingram, L., Wright, G. P., …Florida-James, G. D. (2017). Lower Resting and Exercise-Induced Circulating Angiogenic Progenitors and Angiogenic T-Cells in Older Men. American journal of physiology. Heart and circulatory physiology, doi:10.1152/ajpheart.00592.2017. ISSN 0363-6135
Ageing is associated with a dysfunctional endothelial phenotype, as well as reduced angiogenic capabilities. Exercise exerts beneficial effects on the cardiovascular system, p...
Ross, M., Tormey, P., Ingram, L., Simpson, R., Malone, E., & Florida-James, G. (2016). A 10 km time trial running bout acutely increases the number of angiogenic T cells in the peripheral blood compartment of healthy males: Acute exercise mobilizes angiogenic T cells. Experimental Physiology, 101(10), (1253-1264). doi:10.1113/ep085771. ISSN 0958-0670
What is the central question of the study?
Are CD31+ angiogenic T (TANG) cells preferentially mobilized in response to acute exercise?
What is the main finding an...
Ross, M., Ingram, L., Tormey, P., & Florida-James, G. (2016). Letter regarding article: ‘Effect of acute exercise on circulating angiogenic cell and microparticle populations’: Letter to the Editor. Experimental Physiology, 101(4), (558-558). doi:10.1113/ep085700. ISSN 0958-0670
No abstract available. Item is letter to the editor.
Wekesa, A. L., Doyle, L. M., Fitzmaurice, D., O’Donovan, O., Phelan, J. P., Ross, M. D., …Harrison, M. (2016). Influence of a low-carbohydrate diet on endothelial microvesicles in overweight women. Applied Physiology, Nutrition, and Metabolism, 41(5), (522-527). doi:10.1139/apnm-2015-0507. ISSN 1715-5312
Low-carbohydrate diets (LCD) are increasing in popularity, but their effect on vascular health has been questioned.
Endothelial microvesicles (EMV) are membrane-derived vesicl...
Ross, M. D., Malone, E., & Florida-James, G. (2015). Vascular Ageing and Exercise: Focus on Cellular Reparative Processes. Oxidative Medicine and Cellular Longevity, 2016, (1-15). doi:10.1155/2016/3583956. ISSN 1942-0900
Ageing is associated with an increased risk of developing noncommunicable diseases (NCDs), such as diabetes and cardiovascular disease (CVD). The increased risk can be attribu...
Harrison, M., Wekesa, A., O'Donovan, O., O'Brien, O., Phelan, J., Ross, M., …Harrison, M. (2014). Predicting Carotid Artery Disease and Plaque Instability from Cell-derived Microparticles. European Journal of Vascular and Endovascular Surgery, 48(5), (489-495). doi:10.1016/j.ejvs.2014.08.007. ISSN 1078-5884
Cell-derived microparticles (MPs) are small plasma membrane-derived vesicles shed from circulating blood cells and may act as novel biomarkers of vascular disease. ...
WEKESA, A. L., ROSS, M. D., PHELAN, J. P., Ross, M. D., Wekesa, A. L., Phelan, J. P., & HARRISON, M. (2013). Resistance Exercise Increases Endothelial Progenitor Cells and Angiogenic Factors. Medicine and Science in Sports and Exercise, 46(1), (16-23). doi:10.1249/mss.0b013e3182a142da. ISSN 0195-9131
Bone marrow-derived endothelial progenitor cells (EPC) are involved in vascular growth and repair. They increase in the circulation after a single bout of aerobic exercise, po...
British Association of Sport and Exercise Sciences
The project will measure circulating white blood cells and progenitor cells in response to an extreme exercise running bout/event/ We will also be quantifying upper respiratory tract symptoms.
The aim of the project is to investigate whether pre-sleep ingestion of honey can improve parameters of sleep and subsequent mood and cognitive performance