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238 results

Putting a balance on the aerosolization debate around SARS-CoV-2

Journal Article
Dancer, S. J., Tang, J. W., Marr, L. C., Miller, S., Morawska, L., & Jimenez, J. L. (2020)
Putting a balance on the aerosolization debate around SARS-CoV-2. Journal of Hospital Infection, 105(3), 569-570. https://doi.org/10.1016/j.jhin.2020.05.014
No abstract available.

Precision Medicine and the Role of Biomarkers of Radiotherapy Response in Breast Cancer

Journal Article
Meehan, J., Gray, M., Martínez-Pérez, C., Kay, C., Pang, L. Y., Fraser, J. A., …Turnbull, A. K. (2020)
Precision Medicine and the Role of Biomarkers of Radiotherapy Response in Breast Cancer. Frontiers in Oncology, 10, https://doi.org/10.3389/fonc.2020.00628
Radiotherapy remains an important treatment modality in nearly two thirds of all cancers, including the primary curative or palliative treatment of breast cancer. Unfortunatel...

Bacterial Transfer To Fingertips During Sequential Surface Contacts With And Without Gloves

Journal Article
King, M., López‐García, M., Atedoghu, K. P., Zhang, N., Wilson, A. M., Weterings, M., …Fletcher, L. A. (in press)
Bacterial Transfer To Fingertips During Sequential Surface Contacts With And Without Gloves. Indoor Air, https://doi.org/10.1111/ina.12682
Bacterial transmission from contaminated surfaces via hand contact plays a critical role in disease spread. However, the fomite‐to‐finger transfer efficiency of microorganisms...

Reducing hand recontamination of healthcare workers during COVID-19

Journal Article
Gon, G., Dancer, S., Dreibelbis, R., Graham, W. J., & Kilpatrick, C. (2020)
Reducing hand recontamination of healthcare workers during COVID-19. Infection Control and Hospital Epidemiology, 41(7), 870-871. https://doi.org/10.1017/ice.2020.111
No abstract available.

Dynamic Transmission of Staphylococcus Aureus in the Intensive Care Unit

Journal Article
Adams, C. E., & Dancer, S. J. (2020)
Dynamic Transmission of Staphylococcus Aureus in the Intensive Care Unit. International Journal of Environmental Research and Public Health, 17(6), https://doi.org/10.3390/ijerph17062109
Staphylococcus aureus is an important bacterial pathogen. This study utilized known staphylococcal epidemiology to track S. aureus between patients, surfaces, staff hands and ...

Revising Nightingale's legacy

Journal Article
Dancer, S. (2020)
Revising Nightingale's legacy. Journal of Hospital Infection, 105(2), ‏ 344-345. https://doi.org/10.1016/j.jhin.2020.03.016
The recent editorial from this Journal does well to highlight the benefits of hand hygiene once again [ 1 ]. It is entirely appropriate to support the need for clean hands, es...

Measuring environmental contamination in critical care using dilute hydrogen peroxide (DHP) technology: An observational cross-over study

Journal Article
Oon, A., Reading, E., Ferguson, J., Dancer, S., & Mitchell, B. (2020)
Measuring environmental contamination in critical care using dilute hydrogen peroxide (DHP) technology: An observational cross-over study. Infection, Disease & Health, 25(2), 107-112. https://doi.org/10.1016/j.idh.2019.12.005
Background The environment has an important role in the transmission of healthcare associated infections. This has encouraged interest in novel methods to improve hygiene in h...

Design of a New Peptide Substrate Probe of the Putative Biomarker Legumain with Potential Application in Prostate Cancer Diagnosis ex vivo

Journal Article
Mathur, S., Turnbull, A., Akaev, I., Stevens, C., Agrawal, N., Chopra, M., & Mincher, D. (in press)
Design of a New Peptide Substrate Probe of the Putative Biomarker Legumain with Potential Application in Prostate Cancer Diagnosis ex vivo. International Journal of Peptide Research and Therapeutics, https://doi.org/10.1007/s10989-019-09994-1
The lysosomal endoprotease legumain (asparaginyl endoprotease) has been proposed as a putative biomarker in prostate tumours, in which the enzyme is markedly overexpressed. Ov...

In situ characterization of nanoscale strains in loaded whole joints via synchrotron X-ray tomography

Journal Article
Madi, K., Staines, K., Bay, B., Javaheri, B., Geng, H., Bodey, A., …Lee, P. (2020)
In situ characterization of nanoscale strains in loaded whole joints via synchrotron X-ray tomography. Nature Biomedical Engineering, 4(3), 343-354. https://doi.org/10.1038/s41551-019-0477-1
Imaging techniques for quantifying changes in the hierarchical structure of deforming joints are constrained by destructive sample treatments, sample-size restrictions and len...

Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential

Journal Article
Sharma, A., Goring, A., Staines, K., Emery, R., Pitsillides, A. A., Oreffo, R. O., …Clarkin, C. E. (2020)
Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential. Matrix Biology Plus, 5(February 2020), https://doi.org/10.1016/j.mbplus.2019.100018
Mineralization of bone is achieved by the sequential maturation of the immature amorphous calcium phase to mature hydroxyapatite and is central to the process of bone developm...
27 results

Biochemical Society Summer Vacation Scholarship

2017 - 2017
Nrf2, a transcriptional activator of cell protection genes, is an emerging target for neurodegenerative conditions including Alzheimer’s disease (AD). Nrf2 activity is reduced in dementia patients and...
Funder: Biochemical Society | Value: £1,600

Does the gut microbiome play a role in polycystic ovary syndrome?

2017 - 2018
Does the gut microbiome play a role in polycystic ovary syndrome?
Funder: Society for Reproduction and Fertility | Value: £12,250

PCOS and Thyroid dysfunction

2015 - 2015
Undergraduate vacation scholarship application to study the legacy of prenatal programming of polycystic ovary syndrome on postnatal throid function
Funder: Society for Reproduction and Fertility | Value: £2,750

Cathelicidins as novel therapeutic antiviral agents in Rhinovirus infection

2015 - 2017
We have identified the human cathelicidn LL-37 as having potent direct antiviral activity against human rhinovirus (HRV), together with the capacity to alter death pathways in HRV-infected cells, as a...
Funder: Chief Scientists Office | Value: £163,152

PhD studentship for CIRCA

2014 - 2017
Recent genetic discoveries, principally identification of NOD2 and ATG16L1 as susceptibility loci, strongly implicate a dysregulated host response to enteric bacteria and the autophagy pathway in the ...
Funder: Crohn's in Childhood Research Association | Value: £68,577

An examination of current attitudes towards the threat of Schmallenberg virus

2013 - 2014
The aim of this research is to evaluate the current attitude of the farming community in Scotland to the threat of Schmallenberg virus and the willingness to carry out vaccination by way of a question...
Value: £970

Polycystic ovary syndrome (PCOS) developmental model

2010 - 2014
Polycystic ovary syndrome (PCOS) is common: more than one in 1 in 15 young women has this condition. There are many associated health problems including abnormal periods, miscarriages, infertility, ex...
Funder: Medical Research Council | Value: £130,956