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Expression of C-Reactive Protein and Heat-Shock Protein-70 in the Lung Epithelial Cell Line A549, in Response to PM10 Exposure

Journal Article
Ramage, L., & Guy, K. (2004)
Expression of C-Reactive Protein and Heat-Shock Protein-70 in the Lung Epithelial Cell Line A549, in Response to PM10 Exposure. Inhalation Toxicology, 16(6-7), 447-452. https://doi.org/10.1080/08958370490439614
Increased levels of C-reactive protein (CRP) and heat-shock protein-70 (Hsp70) in plasma are known to be associated with an increased risk of cardiovascular disease. In this s...

Serum exposed to nanoparticle carbon black displays increased potential to induce macrophage migration

Journal Article
Barlow, P., Donaldson, K., MacCallum, J., Clouter, A., & Stone, V. (2005)
Serum exposed to nanoparticle carbon black displays increased potential to induce macrophage migration. Toxicology Letters, 155(3), 397-401. https://doi.org/10.1016/j.toxlet.2004.11.006
Objective: To assess whether fine and ultrafine particles (nanoparticles) have the capacity to activate factors in serum that would induce macrophage migration. This is a mode...

Absence of correlation between serum CRP levels and mitochondrial D-loop DNA mutations in gastro-oesophageal adenocarcinoma

Journal Article
Tan, B. H. L., Skipworth, R. J. E., Wheelhouse, N. M., Fearon, K. C. H., & Ross, J. A. (2014)
Absence of correlation between serum CRP levels and mitochondrial D-loop DNA mutations in gastro-oesophageal adenocarcinoma. Journal of Cancer Research and Therapeutics, 10(1), 176-9. https://doi.org/10.4103/0973-1482.131458
INTRODUCTION: Both inflammation and mitochondrial DNA (mtDNA) mutation are thought to play a role in the many human cancers. The aim of this study was to evaluate the relation...

Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages.

Journal Article
Barlow, P. G., Clouter-Baker, A., Donaldson, K., MacCallum, J., & Stone, V. (2005)
Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages. Particle and fibre toxicology, 2(1), 11-24. https://doi.org/10.1186/1743-8977-2-11
Background - Alveolar macrophages are a key cell in dealing with particles deposited in the lungs and in determining the subsequent response to that particle exposure. Nanopar...