Research explorer tool

20 results

Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men

Journal Article
Ross, M., Ingram, L., Taylor, G., Malone, E., Simpson, R. J., West, D., & Florida-James, G. (2018)
Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men. Physiological Reports, 6(12), 1-11. https://doi.org/10.14814/phy2.13697
Aging is associated with elevated cardiovascular disease risk. As a result of aging, endothelial dysfunction develops, partly due to a reduction in vascular regenerative abili...

Diurnal Variation in Physiological and Immune Responses to Endurance Sport in Highly Trained Runners in a Hot and Humid Environment

Journal Article
Boukelia, Z., Gomes, E. C., & Florida-James, G. D. (2018)
Diurnal Variation in Physiological and Immune Responses to Endurance Sport in Highly Trained Runners in a Hot and Humid Environment. Oxidative Medicine and Cellular Longevity, 2018, https://doi.org/10.1155/2018/3402143
Purpose. The purpose of this study was to investigate the physiological and immunological response of highly trained runners to an intense bout of exercise performed at two di...

The physiological demands of Gaelic football.

Journal Article
Florida-James, G., & Reilly, T. (1995)
The physiological demands of Gaelic football. British Journal of Sports Medicine, 29(1), 41-45. doi:10.1136/bjsm.29.1.41
Match-lay demands of Gaelic football and fitness profiles were assessed at club competitive level. English Gaelic football club championship players (n = 11) were assessed for...

A 10 km time trial running bout acutely increases the number of angiogenic T cells in the peripheral blood compartment of healthy males: Acute exercise mobilizes angiogenic T cells

Journal Article
Ross, M., Tormey, P., Ingram, L., Simpson, R., Malone, E., & Florida-James, G. (2016)
A 10 km time trial running bout acutely increases the number of angiogenic T cells in the peripheral blood compartment of healthy males: Acute exercise mobilizes angiogenic T cells. Experimental Physiology, 101(10), 1253-1264. https://doi.org/10.1113/ep085771
New Findings What is the central question of the study? Are CD31+ angiogenic T (TANG) cells preferentially mobilized in response to acute exercise? What is the main finding an...

Blood lactate thresholds and walking/running economy are determinants of backpack-running performance in trained soldiers

Journal Article
Simpson, R. J., Graham, S. M., Connaboy, C., Clement, R., Pollonini, L., & Florida-James, G. D. (2017)
Blood lactate thresholds and walking/running economy are determinants of backpack-running performance in trained soldiers. Applied Ergonomics, 58, 566-572. https://doi.org/10.1016/j.apergo.2016.04.010
We developed a standardized laboratory treadmill protocol for assessing physiological responses to a simulated backpack load-carriage task in trained soldiers, and assessed th...

Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task

Journal Article
Simpson, R. J., Graham, S. M., Florida-James, G. D., Connaboy, C., Clement, R., & Jackson, A. S. (2010)
Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task. Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme, 35(5), 650-656. https://doi.org/10.1139/h10-053
Identifying field measures to estimate backpack load-carriage work intensity in elite soldiers is of interest to the military. This study developed rating of perceived exertio...

Senescent T-lymphocytes are mobilised into the peripheral blood compartment in young and older humans after exhaustive exercise

Journal Article
Simpson, R. J., Cosgrove, C., Ingram, L. A., Florida-James, G. D., Whyte, G. P., Pircher, H., & Guy, K. (2008)
Senescent T-lymphocytes are mobilised into the peripheral blood compartment in young and older humans after exhaustive exercise. Brain, Behavior, and Immunity, 22(4), 544-551. https://doi.org/10.1016/j.bbi.2007.11.002
Senescent T-lymphocytes are antigen-experienced cells that express the killer-cell lectin-like receptor G1 (KLRG1) and/or CD57; fail to clonally expand following further antig...

High-Intensity Exercise Mobilises Senescent T-lymphocytes into the Peripheral Blood Compartment in Young and Old Subjects: 781

Journal Article
Simpson, R. J., Cosgrove, C., Florida-James, G. D., Whyte, G. P., Pircher, H., & Guy, K. (2007)
High-Intensity Exercise Mobilises Senescent T-lymphocytes into the Peripheral Blood Compartment in Young and Old Subjects: 781. Medicine and science in sports and exercise, 39(Supplement), S61. https://doi.org/10.1249/01.mss.0000273140.61651.0b
T-cell senescence occurs during aging as a consequence of chromosome telomere shortening in response to repetitive antigenic stimulation. Senescent T-lymphocytes normally exhi...

Physiological and Anthropometrical Indicators of Backpack Running Performance in ??Elite?? British Soldiers: 1384

Journal Article
Graham, S. M., Simpson, R. J., Clement, R., & Florida-James, G. D. (2007)
Physiological and Anthropometrical Indicators of Backpack Running Performance in ??Elite?? British Soldiers: 1384. Medicine and science in sports and exercise, 39(Supplement), S199. https://doi.org/10.1249/01.mss.0000273743.89788.1f
PURPOSE: To identify indicators of backpack running performance in “elite” British soldiers using an extensive range of physiological and anthropometrical variables. METHODS: ...

Lymphocyte Phenotype Alterations, Pro-Inflammatory Cytokines and Acute Phase Proteins Following Repeated Bouts of Mountainous Hill-Running: 2278

Journal Article
Simpson, R. J., Guy, K., Whyte, G. P., Middleton, N., Black, J. R., Ross, J. A., …Florida-James, G. D. (2006)
Lymphocyte Phenotype Alterations, Pro-Inflammatory Cytokines and Acute Phase Proteins Following Repeated Bouts of Mountainous Hill-Running: 2278. Medicine and science in sports and exercise, 38(Supplement), S412???S413. https://doi.org/10.1249/00005768-200605001-01739
No abstract available.
6 results

The influence of ultramarathon running event on immune and cardiovascular systems

2017 - 2018
The project will measure circulating white blood cells and progenitor cells in response to an extreme exercise running bout/event/ We will also be quantifying upper respiratory tract symptoms.
Funder: British Association of Sport and Exercise Sciences | Value: £1,900

Efficacy of the descent master training machine

2018 - 2018
Descent Master is a novel upper body training tool concept, initially created with the mountain bike market in mind, as this activity requires a stable and robust upper body musculature in order to pi...
Funder: Scottish Funding Council | Value: £5,000

Pollution Exposure and Cardiovascular Health

2018 - 2019
The project aims to ascertain pollution exposure on Edinburgh main roads and greener routes, and also determine the health effects of active commuting via these routes
Funder: Carnegie Trust for the Universities of Scotland | Value: £4,550

The influence of aerobic exercise training to attenuate chemotherapy-induced cardiotoxicity and vascular dysfunction in breast cancer and leukaemia patients

2018 - 2021
This project will be based in the Sport, Exercise and Health Research theme within the School of Applied Sciences, and is led by Dr. Mark Ross, Miss Karen Campbell and Professor Geraint Florida-James ...
Funder: ENU Development Trust | Value: £58,079

Participation in Mountain Biking - effects on aspects of psychological wellbeing of young participants

2018 - 2018
Participation in Mountain Biking - effects on aspects of psychological wellbeing of young participants
Funder: Scottish Cycling | Value: £4,999

BikeSenz: getting to grips with cyclists' comfort.

2019 - 2019
Although the overall benefits of cycling to health and wellbeing are well understood, the prevalence of several painful and debilitating injuries of the wrist, including ulnar neuropathy and carpal tu...
Funder: Scottish Funding Council | Value: £4,999
6 results

The role of exercise and age on vitamin D metabolism

2015 - 2019
My main area of research interest is the role of exercise and ageing on vitamin D metabolism. Scotland is identified as a vitamin D deficient nation...
Dr Hannah Margaret Lithgow | Director of Studies: Dr Melanie Leggate | Second Supervisor: Prof Geraint Florida-James

The influence of age, aerobic fitness, cardiovascular risk factors and cytomegalovirus on angiogenic T cells and endothelial progenitor cells

2011 - 2016
Dr Mark Ross | Director of Studies: Prof Geraint Florida-James | Second Supervisor: Dr Eva Malone

The combined effect of high intensity intermittent training and vitamin D supplementation of insulin sensitivity in overweight and obese males and females

2014 - 2016
Dr Hannah Margaret Lithgow | Director of Studies: Dr Melanie Leggate | Second Supervisor: Prof Geraint Florida-James

Sleep disruption, immune cell redeployment and endocrine response following an acute bout of exercise

2007 - 2016
Dr Lesley Ingram-Sills | Director of Studies: Prof Geraint Florida-James | Second Supervisor: Dr Eva Malone

A qualitative exploration of the South African cricket development environment

2011 - 2017
Dr Cedric English | Director of Studies: Prof Russell Martindale | Second Supervisor: Christine Nash

Ambulatory physiological assessment: an ergonomic approach to the dynamic work environment and temporal variability in heart rate variability, blood pressure and the cortisol awakening response.

2011 - 2015
Dr Tom Campbell | Director of Studies: Prof Geraint Florida-James | Second Supervisor: Dr Tony Westbury