Professor of Immunology & Infection / Head of Research, School of Applied Sciences
Barlow, P. G., Brown, D. M., Donaldson, K., MacCallum, J., & Stone, V. (2008). Reduced alveolar macrophage migration induced by acute ambient particle (PM10) exposure. Cell Biology and Toxicology, 24(3), (243-252). doi:10.1007/s10565-007-9033-y. ISSN 0742-2091
Increased levels of particulate air pollution (PM10) have been implicated as a causal agent in pulmonary disease exacerbation and increased deaths from respiratory and cardiov...
Wilson, M. R., Foucaud, L., Barlow, P. G., Hutchison, G. R., Sales, J., Simpson, R. J., & Stone, V. (2007). Nanoparticle interactions with zinc and iron: Implications for toxicology and inflammation. Toxicology and Applied Pharmacology, 225(1), (80-89). doi:10.1016/j.taap.2007.07.012. ISSN 0041-008X
Particulate air pollution (PM10) consists of a mixture of components, including nanoparticles and metals. Studies from our laboratory have demonstrated that transition metals ...
Brown, D., Hutchison, G., Stone, V. & Barlow, P. (2006). Proinflammatory effects of particles on macrophages and epithelial cells. In Particle Toxicology, 183-196. Informa UK Limited. doi:10.1201/9781420003147.ch9. ISBN 978-0-8493-5092-4; 978-1-4200-0314-7
TRANSFORM - Education reform project – Improving Research capability in the Sri Lankan Higher Education sector.
assist the development of a novel electrolysed water based application to reduce spoilage and microbial contamination of a variety of fresh produce types of importance to Indian commerce.
Chief Scientists Office
We have identified the human cathelicidn LL-37 as having potent direct antiviral activity against human rhinovirus (HRV), together with the capacity to alter death pathways in HRV-infected cells, as a...
Barlow, P. G., Li, Y., Wilkinson, T. S., Bowdish, D. M. E., Lau, Y. E., Cosseau, C., …Davidson, D. J. (2006). The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system. Journal of Leukocyte Biology, 80(3), (509-520). doi:10.1189/jlb.1005560. ISSN 0741-5400
The human cathelicidin LL-37 is a cationic host defense peptide (antimicrobial peptide) expressed primarily by neutrophils and epithelial cells. This peptide, up-regulated und...
Barlow, P. G., Clouter-Baker, A., Donaldson, K., MacCallum, J., & Stone, V. (2005). Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages. Particle and fibre toxicology, 2(1), (11-24). doi:10.1186/1743-8977-2-11. ISSN 1743-8977
Background - Alveolar macrophages are a key cell in dealing with particles deposited in the lungs and in determining the subsequent response to that particle exposure. Nanopar...
Barlow, P., Donaldson, K., MacCallum, J., Clouter, A., & Stone, V. (2005). Serum exposed to nanoparticle carbon black displays increased potential to induce macrophage migration. Toxicology Letters, 155(3), (397-401). doi:10.1016/j.toxlet.2004.11.006. ISSN 0378-4274
To assess whether fine and ultrafine particles (nanoparticles) have the capacity to activate factors in serum that would induce macrophage migration. This is a mode...
Sousa, F. H., Casanova, V., Stevens, C., & Barlow, P. G. (2016). Antiviral host defence peptides. In R. M. Epand (Ed.), Host Defense Peptides and Their Potential as Therapeutic Agents, 57-94. Springer Verlag. https://doi.org/10.1007/978-3-319-32949-9_3
The on going global mortality and morbidity associated with viral pathogens highlights the need for the continued development of effective, novel antiviral molecules. The anti...
Donaldson, K., Hibbs, L., Heal, M., Tran, C. L., Lightbody, J., Barlow, P. G., …Stone, V. (2003). Pro-inflammatory interactions between particles, metals and lung cells. In Effects of Air Contaminants on the Respiratory Tract - Interpretations from Molecules to Meta Analysis, 245-258. ISBN 978-3-8167-6478-6
No abstract available.