Researching effective approaches to cleaning in hospitals: protocol of the REACH study, a multi-site stepped-wedge randomised trial
Journal Article
Hall, L., Farrington, A., Mitchell, B. G., Barnett, A. G., Halton, K., Allen, M., …Graves, N. (2016)
Researching effective approaches to cleaning in hospitals: protocol of the REACH study, a multi-site stepped-wedge randomised trial. Implementation Science, 11(1), https://doi.org/10.1186/s13012-016-0406-6
Background
The Researching Effective Approaches to Cleaning in Hospitals (REACH) study will generate evidence about the effectiveness and cost-effectiveness of a novel cleanin...
What are the threats from antimicrobial resistance for maternity units in low- and middle- income countries?
Journal Article
Graham, W. J., Afsana, K., Campbell, O. M. R., Graham, W. J., Morrison, E., Dancer, S., …Woodd, S. (2016)
What are the threats from antimicrobial resistance for maternity units in low- and middle- income countries?. Global Health Action, 9(1), 33381. https://doi.org/10.3402/gha.v9.33381
No abstract available.
Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise
Journal Article
Campbell, J. P., Guy, K., Cosgrove, C., Florida-James, G., & Simpson, R. J. (2008)
Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise. Brain, Behavior, and Immunity, 22(3), 375-380. https://doi.org/10.1016/j.bbi.2007.09.001
Cytotoxic T-lymphocytes co-express the T-cell receptor, CD3 and the MHC I restricted antigen CD8. Although total CD8 expression is often used to identify CD8+ T-cells in blood...
The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4
Journal Article
Brown, D. M., HUTCHISON, L., DONALDSON, K., MACKENZIE, S., DICK, C., & STONE, V. (2007)
The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4. Toxicology Letters, 168(1), 1-6. doi:10.1016/j.toxlet.2006.10.016
Reactive oxygen species (ROS) have been implicated in various pulmonary diseases by causing direct injury to lung epithelial cells. Signalling activity of cells through transc...
The influence of particle composition and size on in vitro and in vivo biological models.
Report
Lightbody, J., Hutchison, G. R., Donaldson, K., & Stone, V. (2003)
The influence of particle composition and size on in vitro and in vivo biological models
Particulate air pollution has been consistently linked with an increase in morbidity and mortality due to respiratory complications and cardiovascular disease. The aim of this...
Variation in hospital cleaning practice and process in Australian hospitals: A structured mapping exercise
Journal Article
Mitchell, B. G., Farrington, A., Allen, M., Gardner, A., Hall, L., Barnett, A. G., …Graves, N. (2017)
Variation in hospital cleaning practice and process in Australian hospitals: A structured mapping exercise. Infection, Disease & Health, https://doi.org/10.1016/j.idh.2017.08.001
Background
The purpose of this paper is to highlight the range of cleaning practices and processes in 11 Australian hospitals and to discuss the challenges this variation pose...
Interactions between ultrafine particles and transition metals in vivo and in vitro.
Journal Article
Wilson, M. R., Lightbody, J., Donaldson, K., Sales, J., & Stone, V. (2002)
Interactions between ultrafine particles and transition metals in vivo and in vitro. Toxicology and Applied Pharmacology, 184, 172-179. https://doi.org/10.1006/taap.2002.9501
Both the ultrafine particle and transition metal components of particulate air pollution (PM10) have been hypothesized to be important factors in determining toxicity and pote...
The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.
Journal Article
Palmer, C., Cotton, L., & Henley, J. M. (2005)
The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Pharmacological Reviews, 57, 253-277. https://doi.org/10.1124/pr.57.2.7
-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) are of fundamental importance in the brain. They are responsible for the majority of fast excitatory synapti...
Dos and don’ts for hospital cleaning
Journal Article
Dancer, S. J. (2016)
Dos and don’ts for hospital cleaning. Current Opinion in Infectious Diseases, 29(4), 415-423. https://doi.org/10.1097/qco.0000000000000289
Purpose of review: More evidence is emerging on the role of cleaning and decontamination for reducing hospital-acquired infection. Timely and adequate removal of environmental...
Design, synthesis and evaluation of novel endoprotease-activated prodrugs and fluorogenic probes with theranostic applications in chemotherapy
Thesis
Ding, Y. Design, synthesis and evaluation of novel endoprotease-activated prodrugs and fluorogenic probes with theranostic applications in chemotherapy. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/7555
Proteolytic degradation of the extracellular matrix (ECM) by overexpressed endoproteases, notably the matrix metalloproteinase MMP-9 and legumain (human asparaginyl endopeptid...