Research explorer tool

16 results

Is it worth screening elective orthopaedic patients for carriage of Staphylococcus aureus ? A part-retrospective case–control study in a Scottish hospital

Journal Article
Dancer, S. J., Christison, F., Eslami, A., Gregori, A., Miller, R., Perisamy, K., …Graves, N. (2016)
Is it worth screening elective orthopaedic patients for carriage of Staphylococcus aureus ? A part-retrospective case–control study in a Scottish hospital. BMJ Open, 6(9), https://doi.org/10.1136/bmjopen-2016-011642
Background With recent focus on methicillin-resistant Staphylococcus aureus (MRSA) screening, methicillin-susceptible S. aureus (MSSA) has been overlooked. MSSA infections are...

Holistic face processing can inhibit recognition of forensic facial composites.

Journal Article
Hancock, P. J. B., Frowd, C. D., Langton, S. R. H., & McIntyre, A. H. (2016)
Holistic face processing can inhibit recognition of forensic facial composites. Law and Human Behavior, 40(2), 128-135. https://doi.org/10.1037/lhb0000160
Facial composite systems help eyewitnesses to show the appearance of criminals. However, likenesses created by unfamiliar witnesses will not be completely accurate, and peopl...

Design, synthesis and evaluation of novel endoprotease-activated prodrugs and fluorogenic probes with theranostic applications in chemotherapy

Thesis
Ding, Y. Design, synthesis and evaluation of novel endoprotease-activated prodrugs and fluorogenic probes with theranostic applications in chemotherapy. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/7555
Proteolytic degradation of the extracellular matrix (ECM) by overexpressed endoproteases, notably the matrix metalloproteinase MMP-9 and legumain (human asparaginyl endopeptid...

The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4

Journal Article
Brown, D. M., HUTCHISON, L., DONALDSON, K., MACKENZIE, S., DICK, C., & STONE, V. (2007)
The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4. Toxicology Letters, 168(1), 1-6. doi:10.1016/j.toxlet.2006.10.016
Reactive oxygen species (ROS) have been implicated in various pulmonary diseases by causing direct injury to lung epithelial cells. Signalling activity of cells through transc...

What are the threats from antimicrobial resistance for maternity units in low- and middle- income countries?

Journal Article
Graham, W. J., Afsana, K., Campbell, O. M. R., Graham, W. J., Morrison, E., Dancer, S., …Woodd, S. (2016)
What are the threats from antimicrobial resistance for maternity units in low- and middle- income countries?. Global Health Action, 9(1), 33381. https://doi.org/10.3402/gha.v9.33381
No abstract available.

Dos and don’ts for hospital cleaning

Journal Article
Dancer, S. J. (2016)
Dos and don’ts for hospital cleaning. Current Opinion in Infectious Diseases, 29(4), 415-423. https://doi.org/10.1097/qco.0000000000000289
Purpose of review: More evidence is emerging on the role of cleaning and decontamination for reducing hospital-acquired infection. Timely and adequate removal of environmental...

Four Steps to Clean Hospitals: Look; Plan; Clean; and Dry

Journal Article
Dancer, S. J., & Kramer, A. (2019)
Four Steps to Clean Hospitals: Look; Plan; Clean; and Dry. Journal of Hospital Infection, 103(1), e1-e8. https://doi.org/10.1016/j.jhin.2018.12.015
Background Now that cleaning and decontamination are recognised as integral to infection control, it is timely to examine the process in more detail. This is because cleaning ...

Researching effective approaches to cleaning in hospitals: protocol of the REACH study, a multi-site stepped-wedge randomised trial

Journal Article
Hall, L., Farrington, A., Mitchell, B. G., Barnett, A. G., Halton, K., Allen, M., …Graves, N. (2016)
Researching effective approaches to cleaning in hospitals: protocol of the REACH study, a multi-site stepped-wedge randomised trial. Implementation Science, 11(1), https://doi.org/10.1186/s13012-016-0406-6
Background The Researching Effective Approaches to Cleaning in Hospitals (REACH) study will generate evidence about the effectiveness and cost-effectiveness of a novel cleanin...

Is there an association between airborne and surface microbes in the critical care environment?

Journal Article
Smith, J., Adams, C., King, M., Noakes, C., Robertson, C., & Dancer, S. (2018)
Is there an association between airborne and surface microbes in the critical care environment?. Journal of Hospital Infection, https://doi.org/10.1016/j.jhin.2018.04.003
Background There are few data and no accepted standards for air quality in the intensive care unit (ICU). Any relationship between airborne pathogens and hospital-acquired inf...

Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease

Journal Article
Kerr, F., Sofola-Adesakin, O., Ivanov, D. K., Gatliff, J., Gomez Perez-Nievas, B., Bertrand, H. C., …Partridge, L. (2017)
Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease. PLoS Genetics, 13(3), https://doi.org/10.1371/journal.pgen.1006593
Nrf2, a transcriptional activator of cell protection genes, is an attractive therapeutic target for the prevention of neurodegenerative diseases, including Alzheimer’s disease...