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The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.

Journal Article
Palmer, C., Cotton, L., & Henley, J. M. (2005)
The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Pharmacological Reviews, 57, 253-277. https://doi.org/10.1124/pr.57.2.7
-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) are of fundamental importance in the brain. They are responsible for the majority of fast excitatory synapti...

The intermediate filament protein, vimentin, is a regulator of NOD2 activity.

Journal Article
Stevens, C., Henderson, P., Nimmo, E. R., Soares, D. C., Dogan, B., Simpson, K. W., …Satsangi, J. (2013)
The intermediate filament protein, vimentin, is a regulator of NOD2 activity. Gut, 62, 695-707. https://doi.org/10.1136/gutjnl-2011-301775
Objective Mutations in the nucleotide-binding oligomerisation domain-containing protein 2 (NOD2) gene remain the strongest genetic determinants for Crohn's disease (CD). Havin...

Substance Related Offending Behaviour Programme (SROBP): an exploration of gender responsivity and treatment acceptance issues for female prisoners.

Journal Article
Mahoney, A., Chouliara, Z., & Karatzias, T. (2015)
Substance Related Offending Behaviour Programme (SROBP): an exploration of gender responsivity and treatment acceptance issues for female prisoners. Journal of Forensic Psychiatry and Psychology, 26, 798-823. https://doi.org/10.1080/14789949.2015.1062993
Substance-related offending poses a considerable problem for society. In response, criminal justice agencies have widely delivered cognitive-behavioural interventions, such as...

What are the threats from antimicrobial resistance for maternity units in low- and middle- income countries?

Journal Article
Graham, W. J., Afsana, K., Campbell, O. M. R., Graham, W. J., Morrison, E., Dancer, S., …Woodd, S. (2016)
What are the threats from antimicrobial resistance for maternity units in low- and middle- income countries?. Global Health Action, 9(1), 33381. https://doi.org/10.3402/gha.v9.33381
No abstract available.

The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4

Journal Article
Brown, D. M., HUTCHISON, L., DONALDSON, K., MACKENZIE, S., DICK, C., & STONE, V. (2007)
The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4. Toxicology Letters, 168(1), 1-6. doi:10.1016/j.toxlet.2006.10.016
Reactive oxygen species (ROS) have been implicated in various pulmonary diseases by causing direct injury to lung epithelial cells. Signalling activity of cells through transc...

Dos and don’ts for hospital cleaning

Journal Article
Dancer, S. J. (2016)
Dos and don’ts for hospital cleaning. Current Opinion in Infectious Diseases, 29(4), 415-423. https://doi.org/10.1097/qco.0000000000000289
Purpose of review: More evidence is emerging on the role of cleaning and decontamination for reducing hospital-acquired infection. Timely and adequate removal of environmental...

An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis.

Journal Article
Brown, D. M., Kinloch, I. A., Bangert, U., Windle, A., Walter, D. M., Walker, G. S., …Stone, V. (2007)
An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis. Carbon, 45, 1743-1756. https://doi.org/10.1016/j.carbon.2007.05.011
There has been little information to date based on the potential health effects and hazards associated with the inhalation of carbon nanofibrous materials by workers despite t...

Assessment of causal link between psychological factors and symptom exacerbation in inflammatory bowel disease: a protocol for systematic review of prospective cohort studies.

Journal Article
Schoultz, M., Atherton, I., Hubbard, G., & Watson, A. J. M. (2013)
Assessment of causal link between psychological factors and symptom exacerbation in inflammatory bowel disease: a protocol for systematic review of prospective cohort studies. Systematic Reviews, 2, https://doi.org/10.1186/2046-4053-2-8
Background Inflammatory bowel disease is an idiopathic chronic disease that affects around 28 million people worldwide. Symptoms are distressing and have a detrimental effect...

A feasibility study of a personalised lifestyle programme (HealthForce) for individuals who have participated in cardiovascular risk screening

Journal Article
Craigie, A. M., Barton, K. L., Macleod, M., Williams, B., van Teijlingen, E., Belch, J. J., & Anderson, A. S. (2011)
A feasibility study of a personalised lifestyle programme (HealthForce) for individuals who have participated in cardiovascular risk screening. Preventive Medicine, 52(5), 387-389. https://doi.org/10.1016/j.ypmed.2011.03.010
Objective. To assess the feasibility of a lifestyle intervention, focusing on diet and activity, in adults participating in cardiovascular screening. Methods. The 12-week li...

Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo.

Journal Article
Taylor, M. D., LeGoff, L., Harris, A., Malone, E. M., Allen, J. E., & Maizels, R. M. (2005)
Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. Journal of Immunology, 174, 4924-4933
Human filarial parasites cause chronic infection associated with long-term down-regulation of the host’s immune response. We show here that CD4+ T cell regulation is the main ...