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The use of mindfulness-based cognitive therapy for improving quality of life for inflammatory bowel disease patients: study protocol for a pilot randomised controlled trial with embedded process evaluation.

Journal Article
Schoultz, M., Atherton, I., Hubbard, G., & Watson, A. J. M. (2013)
The use of mindfulness-based cognitive therapy for improving quality of life for inflammatory bowel disease patients: study protocol for a pilot randomised controlled trial with embedded process evaluation. Trials, 14, 431. https://doi.org/10.1186/1745-6215-14-431
Background Inflammatory bowel disease (IBD) is a chronic condition with an unpredictable disease course. Rates of anxiety and depression among IBD patients in relapse (activ...

Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo.

Journal Article
Taylor, M. D., LeGoff, L., Harris, A., Malone, E. M., Allen, J. E., & Maizels, R. M. (2005)
Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. Journal of Immunology, 174, 4924-4933
Human filarial parasites cause chronic infection associated with long-term down-regulation of the host’s immune response. We show here that CD4+ T cell regulation is the main ...

The intermediate filament protein, vimentin, is a regulator of NOD2 activity.

Journal Article
Stevens, C., Henderson, P., Nimmo, E. R., Soares, D. C., Dogan, B., Simpson, K. W., …Satsangi, J. (2013)
The intermediate filament protein, vimentin, is a regulator of NOD2 activity. Gut, 62, 695-707. https://doi.org/10.1136/gutjnl-2011-301775
Objective Mutations in the nucleotide-binding oligomerisation domain-containing protein 2 (NOD2) gene remain the strongest genetic determinants for Crohn's disease (CD). Havin...

Is it worth screening elective orthopaedic patients for carriage of Staphylococcus aureus ? A part-retrospective case–control study in a Scottish hospital

Journal Article
Dancer, S. J., Christison, F., Eslami, A., Gregori, A., Miller, R., Perisamy, K., …Graves, N. (2016)
Is it worth screening elective orthopaedic patients for carriage of Staphylococcus aureus ? A part-retrospective case–control study in a Scottish hospital. BMJ Open, 6(9), https://doi.org/10.1136/bmjopen-2016-011642
Background With recent focus on methicillin-resistant Staphylococcus aureus (MRSA) screening, methicillin-susceptible S. aureus (MSSA) has been overlooked. MSSA infections are...

Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise

Journal Article
Campbell, J. P., Guy, K., Cosgrove, C., Florida-James, G., & Simpson, R. J. (2008)
Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise. Brain, Behavior, and Immunity, 22(3), 375-380. https://doi.org/10.1016/j.bbi.2007.09.001
Cytotoxic T-lymphocytes co-express the T-cell receptor, CD3 and the MHC I restricted antigen CD8. Although total CD8 expression is often used to identify CD8+ T-cells in blood...

Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines.

Journal Article
Brown, D. M., Wilson, M. R., MacNee, W., Stone, V., & Donaldson, K. (2001)
Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines. Toxicology and Applied Pharmacology, 175, 191-199. https://doi.org/10.1006/taap.2001.9240
Studies into the effects of ultrafine particles in the lung have shown adverse effects considered to be due in part to the particle size. Air pollution particles (PM10) are as...

An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis.

Journal Article
Brown, D. M., Kinloch, I. A., Bangert, U., Windle, A., Walter, D. M., Walker, G. S., …Stone, V. (2007)
An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis. Carbon, 45, 1743-1756. https://doi.org/10.1016/j.carbon.2007.05.011
There has been little information to date based on the potential health effects and hazards associated with the inhalation of carbon nanofibrous materials by workers despite t...

Patient satisfaction with two different models of cancer genetic services in south-east Scotland

Journal Article
Holloway, S., Porteous, M., Cetnarskyj, R., Anderson, E., Rush, R., Fry, A., …Campbell, H. (2004)
Patient satisfaction with two different models of cancer genetic services in south-east Scotland. British Journal of Cancer, 90(3), 582-589. https://doi.org/10.1038/sj.bjc.6601562
There is a need to integrate primary- and secondary-care cancer genetic services, but the most appropriate model of service delivery remains unclear. This study reports patien...

Variation in hospital cleaning practice and process in Australian hospitals: A structured mapping exercise

Journal Article
Mitchell, B. G., Farrington, A., Allen, M., Gardner, A., Hall, L., Barnett, A. G., …Graves, N. (2017)
Variation in hospital cleaning practice and process in Australian hospitals: A structured mapping exercise. Infection, Disease & Health, https://doi.org/10.1016/j.idh.2017.08.001
Background The purpose of this paper is to highlight the range of cleaning practices and processes in 11 Australian hospitals and to discuss the challenges this variation pose...

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21

Journal Article
Tenesa, A., Farrington, S. M., Prendergast, J. G. D., Porteous, M. E., Walker, M., Haq, N., …Dunlop, M. G. (2008)
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nature Genetics, 40, 631-637. https://doi.org/10.1038/ng.133
In a genome-wide association study to identify loci associated with colorectal cancer (CRC) risk, we genotyped 555,510 SNPs in 1,012 early-onset Scottish CRC cases and 1,012 c...