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A qualitative study exploring the views, attitudes and beliefs of patients and health professionals towards exercise intervention for people who are surgically treated for lung cancer

Journal Article
Crandall, K., Maguire, R., Campbell, A., & Kearney, N. (2018)
A qualitative study exploring the views, attitudes and beliefs of patients and health professionals towards exercise intervention for people who are surgically treated for lung cancer. European Journal of Cancer Care, 27(2), e12828. https://doi.org/10.1111/ecc.12828
Surgical removal remains the best curative option for patients diagnosed with early‐stage lung cancer. However, it is also associated with significant morbidity and reduced qu...

Ovulation and Ovarian Cancer

Book Chapter
Hillier, S. G., Rae, M. T., & Gubbay, O. (2008)
Ovulation and Ovarian Cancer. In Hormonal Carcinogenesis V;, 171-178. BMC. https://doi.org/10.1007/978-0-387-69080-3_16
Ovarian cancer (OC) most frequently arises from the ovarian surface epithelium (OSE), which comprises a single layer of mesothelial, squamous-to-cuboidal cells covering the en...

Design and evaluation of novel theranostic fluorogenic dual probe-prodrug in cancer

Journal Article
Mathur, S., Mincher, D., Turnbull, A., Stevens, C., & Poole, A. (2016)
Design and evaluation of novel theranostic fluorogenic dual probe-prodrug in cancer. European Journal of Cancer, 61, S142. https://doi.org/10.1016/s0959-8049%2816%2961501-0
Background: In spite of major advances in the diagnosis and treatment of cancer, there remains a paucity of biomarkers for early detection. Legumain is a potential cancer biom...

Benefits of supervised group exercise programme for women being treated for early stage breast cancer: pragmatic randomised controlled trial

Journal Article
Mutrie, N., Campbell, A. M., Whyte, F., McConnachie, A., Emslie, C., Lee, L., …Ritchie, D. (2007)
Benefits of supervised group exercise programme for women being treated for early stage breast cancer: pragmatic randomised controlled trial. BMJ, 334(7592), 517. https://doi.org/10.1136/bmj.39094.648553.ae
Objectives To determine functional and psychological benefits of a 12 week supervised group exercise programme during treatment for early stage breast cancer, with six month f...

'I wouldn't have been interested in just sitting round a table talking about cancer'; exploring the experiences of women with breast cancer in a group exercise trial

Journal Article
Emslie, C., Whyte, F., Campbell, A., Mutrie, N., Lee, L., Ritchie, D., & Kearney, N. (2007)
'I wouldn't have been interested in just sitting round a table talking about cancer'; exploring the experiences of women with breast cancer in a group exercise trial. Health Education Research, 22(6), 827-838. https://doi.org/10.1093/her/cyl159
There is evidence that physical activity improves the psychological and physical health of patients with cancer. However, relatively little attention has been paid to understa...

Recruitment to the “Breast—Activity and Healthy Eating After Diagnosis” (B-AHEAD) Randomized Controlled Trial

Journal Article
Pegington, M., Adams, J. E., Bundred, N. J., Harvie, M. N., Campbell, A., Howell, A., …Harvey, M. (2018)
Recruitment to the “Breast—Activity and Healthy Eating After Diagnosis” (B-AHEAD) Randomized Controlled Trial. Integrative Cancer Therapies, 17(1), 131-137. https://doi.org/10.1177/1534735416687850
Excess weight at breast cancer diagnosis and weight gain during treatment are linked to increased breast cancer specific and all-cause mortality. The Breast—Activity and Healt...

Design, synthesis and evaluation of novel endoprotease-activated prodrugs and fluorogenic probes with theranostic applications in chemotherapy

Thesis
Ding, Y. Design, synthesis and evaluation of novel endoprotease-activated prodrugs and fluorogenic probes with theranostic applications in chemotherapy. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/7555
Proteolytic degradation of the extracellular matrix (ECM) by overexpressed endoproteases, notably the matrix metalloproteinase MMP-9 and legumain (human asparaginyl endopeptid...

The Cancer Rehabilitation Journey: Barriers to and Facilitators of Exercise Among Patients With Cancer-Related Fatigue

Journal Article
Blaney, J., Lowe-Strong, A., Rankin, J., Campbell, A., Allen, J., & Gracey, J. (2010)
The Cancer Rehabilitation Journey: Barriers to and Facilitators of Exercise Among Patients With Cancer-Related Fatigue. Physical Therapy, 90(8), 1135-1147. https://doi.org/10.2522/ptj.20090278
Background Despite the evidence to support exercise as an effective management strategy for patients with cancer-related fatigue (CRF), many of the general cancer population a...

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling

Journal Article
Sandilands, E., Serrels, B., McEwan, D. G., Morton, J. P., Macagno, J. P., McLeod, K., …Frame, M. C. (2012)
Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling. Nature Cell Biology, 14(1), 51-60. https://doi.org/10.1038/ncb2386
Here we describe a mechanism that cancer cells use to survive when flux through the Src/FAK pathway is severely perturbed. Depletion of FAK, detachment of FAK-proficient cells...

Targeting an MMP-9-activated prodrug to multiple myeloma diseased bone marrow: a proof of principle in the 5T33MM mouse model.

Journal Article
Van Valckenborgh, E., Mincher, D., Di Salvo, A., Van Riet, I., Young, L., Van Camp, B., & Vanderkerken, K. (2005)
Targeting an MMP-9-activated prodrug to multiple myeloma diseased bone marrow: a proof of principle in the 5T33MM mouse model. Leukemia, 19, 1628-1633. https://doi.org/10.1038/sj.leu.2403866
Multiple myeloma (MM) is an incurable B-cell cancer characterised by the monoclonal proliferation of tumour cells in the bone marrow (BM). It has been described that matrix me...