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Regulation and Function of the Original p53- Inducible p21 Gene

Book Chapter
Fraser, J. A. (2010)
Regulation and Function of the Original p53- Inducible p21 Gene. In p53; Molecular Biology Intelligence Unit, 100-116. Springer Science + Business Media. https://doi.org/10.1007/978-1-4419-8231-5_7
P21 is a well known regulator of cell cycle progression through its inhibitory actions on Cyclin dependent kinases, (Cdk)/cyclin complexes, and DNA replication via its binding...

Experimental challenge of pregnant cattle with the putative abortifacient Waddlia chondrophila

Journal Article
Wheelhouse, N., Flockhart, A., Aitchison, K., Livingstone, M., Finlayson, J., Flachon, V., …Longbottom, D. (2016)
Experimental challenge of pregnant cattle with the putative abortifacient Waddlia chondrophila. Scientific Reports, 6, 37150. https://doi.org/10.1038/srep37150
Waddlia chondrophila is a Gram-negative intracellular bacterial organism that is related to classical chlamydial species and has been implicated as a cause of abortion in catt...

Nanoparticle interactions with zinc and iron: Implications for toxicology and inflammation

Journal Article
Wilson, M. R., Foucaud, L., Barlow, P. G., Hutchison, G. R., Sales, J., Simpson, R. J., & Stone, V. (2007)
Nanoparticle interactions with zinc and iron: Implications for toxicology and inflammation. Toxicology and Applied Pharmacology, 225(1), 80-89. https://doi.org/10.1016/j.taap.2007.07.012
Particulate air pollution (PM10) consists of a mixture of components, including nanoparticles and metals. Studies from our laboratory have demonstrated that transition metals ...

Serum exposed to nanoparticle carbon black displays increased potential to induce macrophage migration

Journal Article
Barlow, P., Donaldson, K., MacCallum, J., Clouter, A., & Stone, V. (2005)
Serum exposed to nanoparticle carbon black displays increased potential to induce macrophage migration. Toxicology Letters, 155(3), 397-401. https://doi.org/10.1016/j.toxlet.2004.11.006
Objective: To assess whether fine and ultrafine particles (nanoparticles) have the capacity to activate factors in serum that would induce macrophage migration. This is a mode...

Antiviral host defence peptides.

Book Chapter
Sousa, F. H., Casanova, V., Stevens, C., & Barlow, P. G. (2016)
Antiviral host defence peptides. In R. M. Epand (Ed.), Host Defense Peptides and Their Potential as Therapeutic Agents, 57-94. Springer Verlag. https://doi.org/10.1007/978-3-319-32949-9_3
The on going global mortality and morbidity associated with viral pathogens highlights the need for the continued development of effective, novel antiviral molecules. The anti...

Pathogenic outcome following experimental infection of sheep with Chlamydia abortus variant strains LLG and POS

Journal Article
Livingstone, M., Wheelhouse, N., Ensor, H., Rocchi, M., Maley, S., Aitchison, K., …Longbottom, D. (2017)
Pathogenic outcome following experimental infection of sheep with Chlamydia abortus variant strains LLG and POS. PLOS ONE, 12(5), https://doi.org/10.1371/journal.pone.0177653
This study investigated the pathogenesis of two variant strains (LLG and POS) of Chlamydia abortus, in comparison to a typical wild-type strain (S26/3) which is known to be re...

Activated sludge foaming: The true extent of actinomycete diversity

Journal Article
Goodfellow, M., Stainsby, F., Davenport, R., Chun, J., & Curtis, T. (1998)
Activated sludge foaming: The true extent of actinomycete diversity. Water Science and Technology, 37(4-5), (511-519). doi:10.1016/s0273-1223(98)00153-x. ISSN 0273-1223
Isolates from activated sludge foam were provisionally assigned to the genera Gordona and Tsukamurella on the basis of colony morphology and pigmentation. Representatives of t...

The Effects of Air Pollution Particles on Clearance Mechanisms Within the Lung

Thesis
Barlow, P. G. The Effects of Air Pollution Particles on Clearance Mechanisms Within the Lung. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/Output/1052591
The effects of inhaled aIr pollution particles on lung clearance mechanisms is an important factor in understanding how the mammalian lung deals with such pollutants and, as s...

Factors affecting silver biosorption by an industrial strain of Saccharomyces cerevisiae

Journal Article
Singleton, I., & Simmons, P. (1996)
Factors affecting silver biosorption by an industrial strain of Saccharomyces cerevisiae. Journal of chemical technology and biotechnology, 65(1), 21-28. https://doi.org/10.1002/%28SICI%291097-4660%28199601%2965%3A13.0.CO%3B2-E
Factors affecting silver biosorption by Saccharomyces cerevisiae biomass, obtained as a waste product from industry, were examined. Maximum removal of silver from solution was...

Sources and survival of Listeria monocytogenes on fresh, leafy produce

Journal Article
on fresh, leafy produce. Journal of Applied Microbiology, 125(4), 930-942. https://doi.org/10.1111/jam.14025

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on fresh, leafy produce. Journal of Applied Microbiology, 125(4), 930-942. https://doi.org/10.1111/jam.14025
Listeria monocytogenes in an intracellular human pathogen which enters the body through contaminated food stuffs and is known to contaminate fresh leafy produce such as spinac...
25 results

Beach sand as potential resevoirs of antibiotic resistant hospital pathogens

2015 - 2015
Students into Work Vacation Studentship 2015
Funder: Society of Applied Microbiology | Value: £2,100

Electrolysed Water for Post-Harvest Washing (JadooJal)

2017 - 2019
assist the development of a novel electrolysed water based application to reduce spoilage and microbial contamination of a variety of fresh produce types of importance to Indian commerce.
Funder: Innovate UK | Value: £231,163

Artisan Cheese making

2016 - 2016
The project objectives and scope are (i) to establish a knowledge base of current practice in starter culture use and possible bacteriophage-related issues in the artisanal cheese-making sector in Sco...
Funder: Scottish Funding Council | Value: £9,678

Beltane Public Engagement Fellowships

2015 - 2015
To embed Public Engagement (PE) as a core part of good teaching, learning, research and knowledge exchange.To support staff and students to become confident practitioners in PE by development of a net...
Funder: Beltane Public Engagement | Value: £8,000

Investigation of STM3071 function in Salmonella

2015 - 2015
Students into Work Vacation Studentship 2015
Funder: Society of Applied Microbiology | Value: £2,681

Development of a UK-Brazil partnership to tackle fungal food spoilage and improve food security - FAPESP

2016 - 2018
Development of a UK-Brazil partnership to tackle fungal food spoilage and improve food security
Funder: Biotechnology and Biological Sciences Research Council

Measuring activity of lytic proteins from bacteriophage infecting R. equi as a possible antimicrobial tool

2017 - 2017
SFAM students and graduates into work grant
Funder: Society of Applied Microbiology | Value: £2,500

Wild Birds as Transmission Vectors for Antimicrobial Resistant in the Environment

2017 - 2017
sfam Student into work grant
Funder: Society of Applied Microbiology | Value: £2,500

Supporting Evidence Based Interventions

2017 - 2019
Supporting Evidence Based Interventions
Funder: University of Glasgow | Value: £6,500

Acceptability of extragenital Chlamydia testing

2017 - 2018
Chlamydia trachomatis is the most common sexually transmitted infection in Scotland, and has significant long‐term consequences to reproductive health. Recent studies suggest that in addition to the g...
Funder: Chief Scientists Office | Value: £27,998