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631 results

Design and evaluation of novel theranostic fluorogenic dual probe-prodrug in cancer

Journal Article
Mathur, S., Mincher, D., Turnbull, A., Stevens, C., & Poole, A. (2016)
Design and evaluation of novel theranostic fluorogenic dual probe-prodrug in cancer. European Journal of Cancer, 61, S142. https://doi.org/10.1016/s0959-8049%2816%2961501-0
Background: In spite of major advances in the diagnosis and treatment of cancer, there remains a paucity of biomarkers for early detection. Legumain is a potential cancer biom...

Psychometric properties of the Talent Development Environment Questionnaire with Chinese talented athletes

Journal Article
Li, C., Martindale, R., Wu, Y., & Si, G. (2017)
Psychometric properties of the Talent Development Environment Questionnaire with Chinese talented athletes. Journal of Sports Sciences, 36(1), 79-85. https://doi.org/10.1080/02640414.2017.1282619
The development of talented athletes is a priority for many countries across the world, including China. A validated Chinese 5-factor Talent Development Environment Questionna...

The relationship between the golf swing plane and ball impact characteristics using trajectory ellipse fitting

Journal Article
Wallace, E. S., Morrison, A., McGrath, D., & Wallace, E. S. (2018)
The relationship between the golf swing plane and ball impact characteristics using trajectory ellipse fitting. Journal of Sports Sciences, 36(3), 303-310. https://doi.org/10.1080/02640414.2017.1303187
The trajectory of the clubhead close to ball impact during the golf swing has previously been shown to be planar. However, the relationship between the plane orientation and t...

DAPK-1 Bbnding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing

Journal Article
Harrison, B., Kraus, M., Burch, L., Stevens, C., Craig, A., Gordon-Weeks, P., & Hupp, T. R. (2008)
DAPK-1 Bbnding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing. Journal of Biological Chemistry, 283(15), 9999-10014. https://doi.org/10.1074/jbc.M706040200
DAPK-1 (death-activated protein kinase) has wide ranging functions in cell growth control; however, DAPK-1 interacting proteins that mediate these effects are not well defined...

Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease

Journal Article
Kerr, F., Sofola-Adesakin, O., Ivanov, D. K., Gatliff, J., Gomez Perez-Nievas, B., Bertrand, H. C., …Partridge, L. (2017)
Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease. PLoS Genetics, 13(3), https://doi.org/10.1371/journal.pgen.1006593
Nrf2, a transcriptional activator of cell protection genes, is an attractive therapeutic target for the prevention of neurodegenerative diseases, including Alzheimer’s disease...

Reliability of the Kinetics of British Army Foot-Drill in Untrained Personnel

Journal Article
Rawcliffe, A. J., Simpson, R. J., Graham, S. M., Psycharakis, S. G., Moir, G. L., & Connaboy, C. (2017)
Reliability of the Kinetics of British Army Foot-Drill in Untrained Personnel. Journal of strength and conditioning research, 31(2), 435-444. https://doi.org/10.1519/jsc.0000000000001492
The purpose of this study was to quantify the reliability of kinetic variables of British Army foot drill performance within untrained civilians and report the magnitude of ve...

High-Intensity Exercise Mobilises Senescent T-lymphocytes into the Peripheral Blood Compartment in Young and Old Subjects: 781

Journal Article
Simpson, R. J., Cosgrove, C., Florida-James, G. D., Whyte, G. P., Pircher, H., & Guy, K. (2007)
High-Intensity Exercise Mobilises Senescent T-lymphocytes into the Peripheral Blood Compartment in Young and Old Subjects: 781. Medicine and science in sports and exercise, 39(Supplement), S61. https://doi.org/10.1249/01.mss.0000273140.61651.0b
T-cell senescence occurs during aging as a consequence of chromosome telomere shortening in response to repetitive antigenic stimulation. Senescent T-lymphocytes normally exhi...

The MDM2 Ubiquitination Signal in the DNA-Binding Domain of p53 Forms a Docking Site for Calcium Calmodulin Kinase Superfamily Members

Journal Article
Craig, A. L., Chrystal, J. A., Fraser, J. A., Sphyris, N., Lin, Y., Harrison, B. J., …Hupp, T. R. (2007)
The MDM2 Ubiquitination Signal in the DNA-Binding Domain of p53 Forms a Docking Site for Calcium Calmodulin Kinase Superfamily Members. Molecular and Cellular Biology, 27(9), 3542-3555. https://doi.org/10.1128/mcb.01595-06
Genetic and biochemical studies have shown that Ser20 phosphorylation in the transactivation domain of p53 mediates p300-catalyzed DNA-dependent p53 acetylation and B-cell tum...

Physiological and Anthropometrical Indicators of Backpack Running Performance in ??Elite?? British Soldiers: 1384

Journal Article
Graham, S. M., Simpson, R. J., Clement, R., & Florida-James, G. D. (2007)
Physiological and Anthropometrical Indicators of Backpack Running Performance in ??Elite?? British Soldiers: 1384. Medicine and science in sports and exercise, 39(Supplement), S199. https://doi.org/10.1249/01.mss.0000273743.89788.1f
PURPOSE: To identify indicators of backpack running performance in “elite” British soldiers using an extensive range of physiological and anthropometrical variables. METHODS: ...

Maternal nutrient restriction in early pregnancy programs hepatic mRNA expression of growth-related genes and liver size in adult male sheep

Journal Article
Hyatt, M. A., Gopalakrishnan, G. S., Bispham, J., Gentili, S., McMillen, I. C., Rhind, S. M., …Symonds, M. E. (2007)
Maternal nutrient restriction in early pregnancy programs hepatic mRNA expression of growth-related genes and liver size in adult male sheep. Journal of Endocrinology, 192(1), 87-97. https://doi.org/10.1677/joe.1.06801
The liver is a major metabolic and endocrine organ of critical importance in the regulation of growth and metabolism. Its function is determined by a complex interaction of nu...

Date


65 results

Medical Research Scotland - PhD studentship

2015 - 2019
MS is a prevalent disease in Scotland with some 10000 sufferers, but treatment options are limited and often only partially effective (Gourraud et al., 2012). MS is known to influence quality of life...
Funder: Medical Research Scotland | Value: £118,664

Polycystic ovary syndrome (PCOS) developmental model

2010 - 2014
Polycystic ovary syndrome (PCOS) is common: more than one in 1 in 15 young women has this condition. There are many associated health problems including abnormal periods, miscarriages, infertility, ex...
Funder: Medical Research Council | Value: £130,956

PhD studentship for CIRCA

2014 - 2017
Recent genetic discoveries, principally identification of NOD2 and ATG16L1 as susceptibility loci, strongly implicate a dysregulated host response to enteric bacteria and the autophagy pathway in the ...
Funder: Crohn's in Childhood Research Association | Value: £68,577

Beach sand as potential resevoirs of antibiotic resistant hospital pathogens

2015 - 2015
Students into Work Vacation Studentship 2015
Funder: Society of Applied Microbiology | Value: £2,100

An examination of current attitudes towards the threat of Schmallenberg virus

2013 - 2014
The aim of this research is to evaluate the current attitude of the farming community in Scotland to the threat of Schmallenberg virus and the willingness to carry out vaccination by way of a question...
Value: £970

Does high intensity intermittent excerise increase fat oxidation post exercise in females

2015 - 2015
Medical Research Scotland (MRS) -Vacation Scholarship 2015
Funder: Medical Research Scotland | Value: £2,000

Cathelicidins as novel therapeutic antiviral agents in Rhinovirus infection

2015 - 2017
We have identified the human cathelicidn LL-37 as having potent direct antiviral activity against human rhinovirus (HRV), together with the capacity to alter death pathways in HRV-infected cells, as a...
Funder: Chief Scientists Office | Value: £163,152

Electrolysed Water for Post-Harvest Washing (JadooJal)

2017 - 2019
assist the development of a novel electrolysed water based application to reduce spoilage and microbial contamination of a variety of fresh produce types of importance to Indian commerce.
Funder: Innovate UK | Value: £231,163

Developing an Evidence-base for Local Policing in Scotland

2012 - 2014
This SIPR IMPAKT bid is made in collaboration with the ACPOS Local Policing Working Group. It is aimed at providing academic support for the development of an evidence-base for local policing in Scotl...
Funder: Scottish Institute for Policing Research | Value: £5,194

Development of Safer Communities Evidence Matrix Scotland

2014 - 2015
The aim of the project was to provide seedcorn funding to expand the Scottish Local Policing Evidence Database (SLoPED) into a larger project, the Safer Communities Evidence Matrix Scotland (SCEMS).
Funder: Scottish Institute for Policing Research | Value: £4,938

Date


Qualification level

12 results

The role of exercise and age on vitamin D metabolism

2015 - 2019
My main area of research interest is the role of exercise and ageing on vitamin D metabolism. Scotland is identified as a vitamin D deficient nation...
Dr Hannah Margaret Lithgow | Director of Studies: Dr Melanie Leggate | Second Supervisor: Prof Geraint Florida-James

Investigating the performance and underlying mechanisms of a novel screening measure for developmental dyslexia: implications for early identification

2013 - 2018
This PhD focuses on the sensorimotor theory of dev...
Dr Barbara Piotrowska | Director of Studies: Dr Jennifer Murray | Second Supervisor: Dr Rory MacLean

The influence of age, aerobic fitness, cardiovascular risk factors and cytomegalovirus on angiogenic T cells and endothelial progenitor cells

2011 - 2016
Dr Mark Ross | Director of Studies: Prof Geraint Florida-James | Second Supervisor: Dr Eva Malone

The combined effect of high intensity intermittent training and vitamin D supplementation of insulin sensitivity in overweight and obese males and females

2014 - 2016
Dr Hannah Margaret Lithgow | Director of Studies: Dr Melanie Leggate | Second Supervisor: Prof Geraint Florida-James

Sleep disruption, immune cell redeployment and endocrine response following an acute bout of exercise

2007 - 2016
Dr Lesley Ingram-Sills | Director of Studies: Prof Geraint Florida-James | Second Supervisor: Dr Eva Malone

An investigation into the nature of psychological resilience in junior athletes

2015 - 2017
A mixed method approach to understanding the nature of psychological resielince in junior athletes, reviewing and proposi...
Dr Hollie Fountain | Director of Studies: Prof Russell Martindale | Second Supervisor: Dr Tony Westbury

The effects of a hockey specific warm up on performance enhancement and injuury prevention

2014 - date
Mr Tom Johnston | Director of Studies: Dr Konstantinos Kaliarntas | Second Supervisor: Dr Susan Brown

A qualitative exploration of the South African cricket development environment

2011 - 2017
Dr Cedric English | Director of Studies: Prof Russell Martindale | Second Supervisor: Christine Nash

Ambulatory physiological assessment: an ergonomic approach to the dynamic work environment and temporal variability in heart rate variability, blood pressure and the cortisol awakening response.

2011 - 2015
Dr Tom Campbell | Director of Studies: Prof Geraint Florida-James | Second Supervisor: Dr Tony Westbury

The Effects of Air Pollution Particles on Clearance Mechanisms within the Lung

2001 - 2005
Prof Peter Barlow | Director of Studies: Vicki Stone
7 results

University teams up with community researchers to help improve their neighbourhood

6 February 2020
A Team of community researchers will join forces with academics to help improve their neighbourhood. UK Research and Innovation today announced its backing for the Seven Kingdoms of Wester Hailes, on...

Dr Lesley Ingram to take on her own bike challenge

10 September 2018
On the 22nd of September Lesley will join 79 others riders to raise money for the STV children's charity appeal.

Dr Lesley Ingram ready to get back in the saddle

10 September 2018
Dr Lesley Ingram will cycle 240 miles for STV children's appeal

ENU Associate Professor co-hosts conference to launch new, ground-breaking book

4 September 2018
Dr Calum Neill will co-host an international conference at Ghent University on the 21st and 22nd of September to launch his new co-edited book, Reading Lacan's Ecrits: From 'Signification of the Phall...

Dr Clare Taylor takes part in expert panel for Evidence Week at UK Parliament

26 June 2018
Dr Clare Taylor, Senior Lecturer in the School of Applied Sciences, was an invited panel member for the event 'Too much evidence or not enough?' organised by Society for Applied Microbiology and Sense...

World Olympians Association launches new health study

18 April 2018
The largest global study into the long-term health issues of Olympians has been launched by the World Olympians Association. More than 10,000 athletes, who no longer compete at Olympic level, are bei...

Dr Peter Barlow appointed to Editorial Board of the Journal of Medical Microbiology

6 July 2017
In July 2017, Dr Peter Barlow was appointed to the Editorial Board of the Journal of Medical Microbiology. The journal, published by the Microbiology Society, covers the full breadth of Clinical Micr...
13 results

Working in Healthcare

Edinburgh Napier University's Sighthill Campus
7 May 2018

Visiting researcher - Katrin Glatz Brubakk (Clinical Psychologist and Assistant Professor at the Norwegian University of Science and Technology) to present on traumatherapy of refugees

Edinburgh Napier University (Sighthill Campus)
6 March 2019

Visiting Professor - Professor Carolyn Emery (University of Calgary) to present on concussion injury prevention in youth sport

Edinburgh Napier University (Sighthill Campus)
2 April 2019

Visiting Professor - Professor Ben Bradford (Global City Policing at the UCL Jill Dando Institute of Security and Crime Science) to present on the effects of stop and search on people and crime

Edinburgh Napier University (Sighthill Campus)
9 June 2019

Visiting researcher - Dr Sjaan Gomersall (Univeristy of Queensland) to present on measuring and influencing physical activity

Edinburgh Napier University (Sighthill Campus)
17 June 2019

Visit from National Biofilms Innovation Centre

Edinburgh Napier University (Sighthill Campus)
3 June 2019

Visiting researcher - Dr Ryan Duffy (University Of Florida) to present on the importance of gratitude at work

Edinburgh Napier University (Sighthill Campus)
24 September 2019

Visiting researcher - Dr Richard Hough (University Of West Florida) to present on legitimacy, accountability and the use of force in American policing

Edinburgh Napier University (Sighthill Campus)
22 September 2019

Visiting researcher - Dr Gemma Pugh (Queen Mary University of London) to present on health behaviour change among teenagers & young adults with cancer

Edinburgh Napier University (Sighthill Campus)
9 October 2019

Seminar with Alan Staff (CEO of Apex Scotland)

Edinburgh Napier University (Sighthill Campus)
15 October 2019