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Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats

Journal Article
McQueen, D. S., Bond, S. M., Smith, P. J., Balali-Mood, K., & Smart, D. (2004)
Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats. European Journal of Pharmacology, 491(2-3), 181-189. https://doi.org/10.1016/j.ejphar.2004.03.045
The results of vasorespiratory studies in rats anaesthetised with pentobarbital show that (±) cannabidiol, a cannabinoid that lacks psychotropic actions and is inactive at can...

Expression of C-Reactive Protein in Human Lung Epithelial Cells and Upregulation by Cytokines and Carbon Particles

Journal Article
Ramage, L., Proudfoot, L., & Guy, K. (2004)
Expression of C-Reactive Protein in Human Lung Epithelial Cells and Upregulation by Cytokines and Carbon Particles. Inhalation Toxicology, 16(9), 607-613. https://doi.org/10.1080/08958370490464599
C-reactive protein (CRP) is the prototypic human acute-phase protein and is found at increased levels in the blood during episodes of inflammation. CRP was generally thought t...

Impact of repeated prolonged exercise bouts on cardiac function and biomarkers.

Journal Article
Middleton, N., Shave, R., George, K., Whyte, G. P., Simpson, R. J., Florida-James, G. & Gaze, D. (2007)
Impact of repeated prolonged exercise bouts on cardiac function and biomarkers. Medicine and Science in Sports and Exercise. 39, 83-90. doi:10.1249/01.mss.0000239395.93578.60. ISSN 0195-9131
Purpose: The present study examined the impact of repeated bouts of prolonged ( Methods: Ten athletes completed a 15.3-mile hill run on three consecutive days and were assesse...

High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects.

Journal Article
Simpson, R. J., Florida-James, G., Cosgrove, C., Whyte, G. P., Macrae, S., Pircher, H. & Guy, K. (2007)
High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects. Journal of Applied Physiology. 103, 396-401. doi:10.1152/japplphysiol.00007.2007. ISSN 15221601
Clonal expansion of T lymphocytes in response to antigenic stimulation is a fundamental process of adaptive immunity. As a consequence of clonal expansion, some T lymphocytes ...

Alpha-1-acid glycoprotein expressed in the plasma of chronic myeloid leukemia patients does not mediate significant in vitro resistance to STI571.

Journal Article
Jørgensen, H. G., Elliott, M. A., Allan, E. K., Carr, C. E., Holyoake, T. L. & Smith, K. (2002)
Alpha-1-acid glycoprotein expressed in the plasma of chronic myeloid leukemia patients does not mediate significant in vitro resistance to STI571. Blood. 99, 713-715. doi:10.1182/blood.V99.2.713. ISSN 0006-4971
Despite the efficacy of STI571 (Glivec, Novartis, Basle, Switzerland) in treating chronic myeloid leukemia (CML), drug resistance has already been noted both in vitro and in v...