Zubala, A., MacGillivray, S., Frost, H., Kroll, T., Skelton, D. A., Gavine, A., …Morris, J. (2017). Promotion of physical activity interventions for community dwelling older adults: A systematic review of reviews. PLoS ONE. 12(7), 1-36. doi:10.1371/journal.pone.0180902. ISSN 1932-6203
Objectives While there is strong evidence that regular participation in physical activity (PA) brings numerous health benefits to older adults, and interventions to effectivel...
Goodbrand, J. A., Hughes, L. D., Cochrane, L., Donnan, P. T., McGilchrist, M., Frost, H., …Witham, M. D. (2017). Association between bisphosphonate therapy and outcomes from rehabilitation in older people. Archives of Gerontology and Geriatrics. 70, 195-200. doi:10.1016/j.archger.2017.01.017. ISSN 0167-4943
Background Bisphosphonate therapy may have actions beyond bone, including effects on cardiovascular, immune and muscle function. We tested whether bisphosphonate treatment is...
Dombrowski, S. U., Campbell, P., Frost, H., Pollock, A., McLellan, J., MacGillivray, S., …Williams, B. (2016). Interventions for sustained healthcare professional behaviour change: a protocol for an overview of reviews. Systematic Reviews. 5(173), 1-6. doi:10.1186/s13643-016-0355-9. ISSN 2046-4053
Background Failure to successfully implement and sustain change over the long term continues to be a major problem in health and social care. Translating evidence into routin...
Basu, U., Goodbrand, J., McMurdo, M. E., Donnan, P. T., McGilchrist, M., Frost, H., …Witham, M. D. (2016). Association between allopurinol use and hip fracture in older patients. BONE. 84, 189-193. doi:10.1016/j.bone.2016.01.003. ISSN 8756-3282
Background Allopurinol reduces oxidative stress and interacts with purinergic signalling systems important in bone metabolism and muscle function. We assessed whether allopur...
Christensen, J. F., Bandak, M., Campbell, A., Jones, L. W. & Højman, P. (2014). Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship. Acta oncologica. 54(5), 592-599. doi:10.3109/0284186X.2014.995776. ISSN 0284-186X
Treatment of testicular germ cell cancer constitutes a major success story in modern oncology. Today, the vast majority of patients are cured by a therapeutic strategy using o...
Trinh, L., Mutrie, N., Campbell, A. M., Crawford, J. J. & Courneya, K. S. (2014). Effects of supervised exercise on motivational outcomes in breast cancer survivors at 5-year follow-up. European Journal of Oncology Nursing. 18(6), 557 - 563. doi:10.1016/j.ejon.2014.07.004. ISSN 1462-3889
Short-term physical activity (PA) has beneficial effects on symptom management and quality of life, however, longer-term adherence is likely needed for improved disease outcom...
Ziebland, S., Featherstone, K., Snowdon, C., Barker, K., Frost, H. & Fairbank, J. (2007). Does it matter if clinicians recruiting for a trial don't understand what the trial is really about? Qualitative study of surgeons' experiences of participation in a pragmatic multi-centre RCT. Trials. 8(1), 1-7. doi:10.1186/1745-6215-8-4. ISSN 1745-6215
Background Qualitative methods are increasingly used to study the process of clinical trials and patients understanding of the rationale for trials, randomisation and reasons...
Mutrie, N., Campbell, A. M., Whyte, F., McConnachie, A., Emslie, C., Lee, L., …Ritchie, D. (2006). Benefits of supervised group exercise programme for women being treated for early stage breast cancer: pragmatic randomised controlled trial. BMJ. 334, 517. doi:10.1136/bmj.39094.648553.AE. ISSN 0959-8138
Objectives To determine functional and psychological benefits of a 12 week supervised group exercise programme during treatment for early stage breast cancer, with six month f...
Rivero-Arias, O., Gray, A., Frost, H., Lamb, S. E. & Stewart-Brown, S. (2006). Cost-Utility Analysis of Physiotherapy Treatment Compared With Physiotherapy Advice in Low Back Pain. Spine. 31(12), 1381-1387. doi:10.1097/01.brs.0000218486.13659.d5. ISSN 0362-2436
Economic evaluation alongside a pragmatic multicenter randomized controlled trial from the National Health Service (NHS) and societal perspective.
Campbell, H., Rivero-Arias, O., Johnston, K., Gray, A., Fairbank, J. & Frost, H. (2006). Responsiveness of Objective, Disease-Specific, and Generic Outcome Measures in Patients With Chronic Low Back Pain: An Assessment for Improving, Stable, and Deteriorating Patients. Spine. 31(7), 815-822. doi:10.1097/01.brs.0000207257.64215.03. ISSN 0362-2436
Analysis of outcome data collected prospectively from 250 patients recruited to the UK Spine Stabilization Trial.
To compare the responsiveness of th...
Frost, H., & Stewart-Brown, S. (2006). Acupressure for low back pain. BMJ, 332(7543), (680-681). doi:10.1136/bmj.332.7543.680. ISSN 0959-8138
Disability associated with low back pain is an important public health problem. Clinical trials carried out in the Western world show conventional treatment t...
Fairbank, J., Frost, H., Wilson-MacDonald, J., Yu, L., Barker, K. & Collins, R. (2005). Randomised controlled trial to compare surgical stabilisation of the lumbar spine with an intensive rehabilitation programme for patients with chronic low back pain: the MRC spine stabilisation trial. BMJ. 330(7502), 1233-0. doi:10.1136/bmj.38441.620417.8f. ISSN 0959-8138
To assess the clinical effectiveness of surgical stabilisation (spinal fusion) compared with intensive rehabilitation for patients with chronic low back pain.
Moffett, J. K., & Frost, H. (2000). Back to Fitness Programme. Physiotherapy, 86(6), (295-305). doi:10.1016/s0031-9406(05)61003-6. ISSN 0031-9406
This paper provides physiotherapists with a manual to set up and run the Back to Fitness programme that was recently evaluated in a trial published in the British Medical Jour...
Graham, S. M., Baird, M. & Boyd, G. W. (2013). Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review. Archives of Exercise in Health and Disease. 4(3), 286-298. doi:10.5628/aehd.v4i3.169. ISSN 1647-1652
Parkinson’s disease (PD) is the second most common progressive neurodegenerative condition after Alzheimer’s Disease. It is characterized by a progressive loss of dopaminergic...
McHale, S. Understanding the lived experience of how individuals aged between 33 and 62 years of age diagnosed with coronary heart disease (CHD) feel they obtain emotional support post percutaneous coronary intervention (PCI). (Thesis)
Coronary Heart Disease (CHD) is a major cause of ill health in Scotland and one of the main methods of symptom management for this disease is Percutaneous Coronary ...