GSK/Edinburgh University

  Neuromodulation can improve ovarian dysfunction in polycystic ovary syndrome (PCOS). This is achieved by four mechanisms: i) if neural signals are involved in LH action directly their modulation may reduce LH action; ii) if neural signals are involved in FSH action directly their modulation may increase FSH action; iii) if neural signals are involved in the maintenance of arrested follicular growth their modulation may reactivate follicur growth; iv) if neural signals are involved in increased ovarian vascularity their modulation may reduce vascularity to promote follicular atresia and loss of the cell mass.
Aims
1) To determine in neuromodulation improves ovarian function in PCOS
2) To assess the mechanism correlates of ovarian neuromodulation

  • Start Date:

    1 September 2015

  • End Date:

    31 August 2018

  • Activity Type:

    Research

  • Funder:

    The University of Edinburgh

  • Value:

    £17518

Project Team