4 results

Expression of Cannabinoid CB1 receptors in models of diabetic neuropathy

Journal Article
Zhang, F., Hong, S., Stone, V., & Smith, P. (2007)
Expression of Cannabinoid CB1 receptors in models of diabetic neuropathy. Journal of Pharmacology and Experimental Therapeutics, 323, 508-515. https://doi.org/10.1124/jpet.107.128272
A clearer understanding of the mechanisms underlying the development and progression of diabetic neuropathy is likely to indicate new directions for the treatment of this comp...

Reduced alveolar macrophage migration induced by acute ambient particle (PM10) exposure

Journal Article
Barlow, P. G., Brown, D. M., Donaldson, K., MacCallum, J., & Stone, V. (2008)
Reduced alveolar macrophage migration induced by acute ambient particle (PM10) exposure. Cell Biology and Toxicology, 24(3), 243-252. https://doi.org/10.1007/s10565-007-9033-y
Increased levels of particulate air pollution (PM10) have been implicated as a causal agent in pulmonary disease exacerbation and increased deaths from respiratory and cardiov...

Role of androgens in fetal testis development and dysgenesis.

Journal Article
Scott, H. M., Hutchison, G. R., Mahood, I. K., Hallmark, N., Welsh, M., De Gendt, K., …Sharpe, R. M. (2007)
Role of androgens in fetal testis development and dysgenesis. Endocrinology. 148, 2027-2036. doi:10.1210/en.2006-1622. ISSN 0013-7227
This study sought to establish whether reduced androgen levels/action in the fetal rat testis induced by di(n-butyl) phthalate (DBP) contributes to dysgenetic features, namely...

The efficacy of certain anti-tuberculosis drugs is affected by binding to alpha-1-acid glycoprotein.

Journal Article
Johnson, D. A. & Smith, K. (2006)
The efficacy of certain anti-tuberculosis drugs is affected by binding to alpha-1-acid glycoprotein. Biomedical Chromatography. 20, 551-560. doi:10.1002/bmc.641. ISSN 0269-3879
One of the most ubiquitous plasma proteins, -1-acid glycoprotein (AGP), has a high affinity, low capacity binding for basic drugs positively charged at physiological pH. Moreo...