Experimental challenge of pregnant cattle with the putative abortifacient Waddlia chondrophila
Journal Article
Wheelhouse, N., Flockhart, A., Aitchison, K., Livingstone, M., Finlayson, J., Flachon, V., …Longbottom, D. (2016)
Experimental challenge of pregnant cattle with the putative abortifacient Waddlia chondrophila. Scientific Reports, 6, 37150. https://doi.org/10.1038/srep37150
Waddlia chondrophila is a Gram-negative intracellular bacterial organism that is related to classical chlamydial species and has been implicated as a cause of abortion in catt...
Cartilage to bone transitions in health and disease
Journal Article
Staines, K. A., Pollard, A. S., McGonnell, I. M., Farquharson, C., & Pitsillides, A. A. (2013)
Cartilage to bone transitions in health and disease. Journal of Endocrinology, 219(1), R1-R12. https://doi.org/10.1530/joe-13-0276
Aberrant redeployment of the 'transient' events responsible for bone development and postnatal longitudinal growth has been reported in some diseases in what is otherwise inhe...
The skeleton: no bones about it
Journal Article
Farquharson, C., & Staines, K. (2011)
The skeleton: no bones about it. Journal of Endocrinology, 211(2), 107-108. doi:10.1530/joe-11-0274
NO abstract available.
NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy
Journal Article
Fox, S., Wilkinson, T. S., Wheatley, P. S., Xiao, B., Morris, R. E., Sutherland, A., …Rossi, A. G. (2010)
NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy. Acta biomaterialia, 6(4), (1515-1521). doi:10.1016/j.actbio.2009.10.038. ISSN 1742-7061
Nitric oxide (NO) is important for the regulation of a number of diverse biological processes, including vascular tone, neurotransmission, inflammatory cell responsiveness, de...
Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages
Journal Article
Li, H., Barlow, P. G., Bylund, J., Mackellar, A., Björstad, Å., Conlon, J., …Davidson, D. J. (2009)
Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages. Journal of Leukocyte Biology, 86(4), 891-902. https://doi.org/10.1189/jlb.0209050
Cathelicidins are CHDP with essential roles in innate host defense but also more recently associated with the pathogenesis of certain chronic diseases. These peptides have mic...
The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system
Journal Article
Barlow, P. G., Li, Y., Wilkinson, T. S., Bowdish, D. M. E., Lau, Y. E., Cosseau, C., …Davidson, D. J. (2006)
The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system. Journal of Leukocyte Biology, 80(3), 509-520. https://doi.org/10.1189/jlb.1005560
The human cathelicidin LL-37 is a cationic host defense peptide (antimicrobial peptide) expressed primarily by neutrophils and epithelial cells. This peptide, up-regulated und...