6 results

Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review

Journal Article
Graham, S. M., Baird, M., & Boyd, G. W. (2014)
Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review. Archives of Exercise in Health and Disease, 4(3), 286-298. https://doi.org/10.5628/aehd.v4i3.169
Parkinson’s disease (PD) is the second most common progressive neurodegenerative condition after Alzheimer’s Disease. It is characterized by a progressive loss of dopaminergic...

Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development.

Journal Article
Girardi, G., Fraser, J. A., Lennen, R., Vontell, R., Jansen, M., & Hutchison, G. (2015)
Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development. Molecular Psychiatry, 20, 1017-1026. https://doi.org/10.1038/mp.2014.110
In the current study, we have developed a magnetic resonance imaging-based method for non-invasive detection of complement activation in placenta and foetal brain in vivo in u...

Exclusion of linkage between idiopathic generalized epilepsies and the GABAA receptor α1 and γ2 subunit gene cluster on chromosome 5

Journal Article
Sander, T., Hildmann, T., Janz, D., Wienker, T. F., Bianchi, A., Bauer, G., …Darlison, M. G. (1996)
Exclusion of linkage between idiopathic generalized epilepsies and the GABAA receptor α1 and γ2 subunit gene cluster on chromosome 5. Epilepsy Research, 23(3), 235-244. https://doi.org/10.1016/0920-1211%2895%2900098-4
Hereditary factors play a major role in the etiology of idiopathic generalized epilepsies (IGEs). The pivotal function of ionotropic γ-aminobutyric acid type A receptors (GABR...

GABAAreceptor subtypes: which, where and why?

Journal Article
Darlison, M. G., & Albrecht, B. E. (1995)
GABAAreceptor subtypes: which, where and why?. Seminars in the neurosciences, 7(2), 115-126. https://doi.org/10.1006/smns.1995.0013
Synaptic inhibition in the vertebrate central nervous system is mediated predominantly by subtypes of the GABAAreceptor, which comprise different pentameric combinations of th...

Isolation and sequence analysis of the chicken GABAa receptor α1-subunit gene promoter

Journal Article
Bateson, A. N., Ultsch, A., & Darlison, M. G. (1995)
Isolation and sequence analysis of the chicken GABAa receptor α1-subunit gene promoter. Gene, 153(2), 243-247. https://doi.org/10.1016/0378-1119%2894%2900776-o
A genomic clone containing the 5'-flanking sequence of the chicken {GABAA} receptor α1-subunit-encoding gene (GabRα1) was isolated and characterized. An intron was found to in...

Cloning and sequence analysis of the pyruvate and 2-oxoglutarate dehydrogenase complex genes ofEscherichia coli

Journal Article
Guest, J. R., Darlison, M. G., Spencer, M. E., & Stephens, P. E. (1984)
Cloning and sequence analysis of the pyruvate and 2-oxoglutarate dehydrogenase complex genes ofEscherichia coli. Biochemical Society Transactions, 12(2), 220-223. https://doi.org/10.1042/bst0120220
No abstract available.