Characterisation of GABAA receptors and cation-chloride cotransporters in the uterus and their role in pre-term labour
Thesis
Sutherland, M. L. Characterisation of GABAA receptors and cation-chloride cotransporters in the uterus and their role in pre-term labour. (Thesis)
Edinburgh napier University. Retrieved from http://researchrepository.napier.ac.uk/Output/1255142
GABAA receptor (GABAAR) function may be inhibitory or excitatory in the brain depending on the chloride electrochemical gradient over the neuronal membrane. This gradient is t...
Interpersonal trauma, substance misuse and pregnancy: A phenomenological exploration of pregnant women and midwives in Scotland
Thesis
Waddell, N. M. Interpersonal trauma, substance misuse and pregnancy: A phenomenological exploration of pregnant women and midwives in Scotland. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/Output/1255223
Background: The relationship between interpersonal trauma (IPT) and substance misuse is complex and multi-factorial, but has not been examined fully in the existing few studie...
Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin β1 to Promote Embryo-tubal Attachment
Journal Article
Ahmad, S. F., Brown, J. K., Campbell, L. L., Koscielniak, M., Oliver, C., Wheelhouse, N., …Horne, A. W. (2018)
Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin β1 to Promote Embryo-tubal Attachment. EBioMedicine, 29, 159-165. https://doi.org/10.1016/j.ebiom.2018.02.020
Tubal ectopic pregnancies are a leading cause of global maternal morbidity and mortality. Previous infection with Chlamydia trachomatis is a major risk factor for tubal embryo...
Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release
Journal Article
Giakoumelou, S., Wheelhouse, N., Brown, J., Wade, J., Simitsidellis, I., Gibson, D., …Horne, A. W. (2017)
Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release. Scientific Reports, 7(1), https://doi.org/10.1038/s41598-017-02223-z
Miscarriage affects ~20% of pregnancies and 30 maternal infections account for ~15% of early miscarriages. Chlamydia trachomatis (Ct) has been associated with miscarriage but ...
Patterns of referral and waiting times for specialist Child and Adolescent Mental Health Services
Journal Article
Smith, J., Kyle, R. G., Daniel, B., & Hubbard, G. (2018)
Patterns of referral and waiting times for specialist Child and Adolescent Mental Health Services. Child and Adolescent Mental Health, 23(1), 41-49. https://doi.org/10.1111/camh.12207
Background
During 12 month period (2012/13) around 21,480 children and young people (CYP) were referred to CAMHS in Scotland (NHS Scotland 2013). At the end of September 2012 ...
Coded rhetoric: The reality of midwifery practice
Journal Article
Group, B. P., Mander, R., & McHugh, N. (2016)
Coded rhetoric: The reality of midwifery practice. British Journal of Midwifery, 24(5), 344-352. https://doi.org/10.12968/bjom.2016.24.5.344
In the light of certain failings in NHS provision of care, the Nursing and Midwifery Council's (NMC, 2015) Code requires staff to engage more effectively with patients and ser...
The role of infection in miscarriage
Journal Article
Giakoumelou, S., Wheelhouse, N., Cuschieri, K., Entrican, G., Howie, S. E., & Horne, A. W. (2016)
The role of infection in miscarriage. Human Reproduction Update, 22(1), 116-133. https://doi.org/10.1093/humupd/dmv041
BACKGROUND: Miscarriage is the spontaneous loss of a pregnancy before 12 weeks (early miscarriage) or from 12 to 24 weeks (late miscarriage) of gestation. Miscarriage occurs i...
In an ovine model of polycystic ovary syndrome (PCOS) prenatal androgens suppress female fetal renal gluconeogenesis.
Journal Article
Kanellopoulos-Langevin, C., Connolly, F., Rae, M. T., Späth, K., Boswell, L., McNeilly, A. S., & Duncan, W. C. (2015)
In an ovine model of polycystic ovary syndrome (PCOS) prenatal androgens suppress female fetal renal gluconeogenesis. PLOS ONE, 10, https://doi.org/10.1371/journal.pone.0132113
Increased maternal androgen exposure during pregnancy programmes a polycystic ovary syndrome (PCOS)-like condition, with metabolic dysfunction, in adult female offspring. Othe...
Pancreatic and adrenal development and function in an ovine model of polycystic ovary syndrome
Thesis
Ramaswamy, S. Pancreatic and adrenal development and function in an ovine model of polycystic ovary syndrome. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/9826
Polycystic Ovary Syndrome (PCOS) is a complex disorder encompassing reproductive and metabolic dysfunction. Ovarian hyperandrogenism is an endocrine hallmark of human PCOS. In...
Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship
Journal Article
Christensen, J. F., Bandak, M., Campbell, A., Jones, L. W., & Højman, P. (2015)
Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship. Acta oncologica, 54(5), 592-599. https://doi.org/10.3109/0284186x.2014.995776
Treatment of testicular germ cell cancer constitutes a major success story in modern oncology. Today, the vast majority of patients are cured by a therapeutic strategy using o...