De novo design of novel protease inhibitor candidates in the treatment of SARS-CoV-2 using deep learning, docking, and molecular dynamic simulations
Journal Article
Arshia, A. H., Shadravan, S., Solhjoo, A., Sakhteman, A., & Sami, A. (2021)
De novo design of novel protease inhibitor candidates in the treatment of SARS-CoV-2 using deep learning, docking, and molecular dynamic simulations. Computers in Biology and Medicine, 139, Article 104967. https://doi.org/10.1016/j.compbiomed.2021.104967
The main protease of SARS-CoV-2 is a critical target for the design and development of antiviral drugs. 2.5 M compounds were used in this study to train an LSTM generative net...
Hardware Design for Autonomous Robot Evolution
Conference Proceeding
Hale, M. F., Angus, M., Buchanan, E., Li, W., Woolley, R., Le Goff, L. K., …Tyrrell, A. M. (2020)
Hardware Design for Autonomous Robot Evolution. In 2020 IEEE Symposium Series on Computational Intelligence (SSCI) (2140-2147). https://doi.org/10.1109/SSCI47803.2020.9308204
The long term goal of the Autonomous Robot Evolution (ARE) project is to create populations of physical robots, in which both the controllers and body plans are evolved. The t...
The effectiveness of cognitive-behavioural interventions at increasing adherence to physical activity in mental health populations: a systematic review
Journal Article
Snowden, A., Peddie, N., & Westbury, T. (2021)
The effectiveness of cognitive-behavioural interventions at increasing adherence to physical activity in mental health populations: a systematic review. Advances in Mental Health, 19(1), 94-112. https://doi.org/10.1080/18387357.2019.1684829
Objective: There is growing global evidence for stark inequalities in the physical health status and life-expectancy of people with a mental health diagnosis. In most cases, p...
Health professionals' lack of knowledge of central venous access devices: the impact on patients
Journal Article
Kelly, L. J., Snowden, A., Paterson, R., & Campbell, K. (2019)
Health professionals' lack of knowledge of central venous access devices: the impact on patients. British Journal of Nursing, 28(14), https://doi.org/10.12968/bjon.2019.28.14.S4
Background
The literature on patient experience of living with a central venous access device (CVAD) is growing, but remains sparse. It suggests that patients accept CVADs as...
A review of the impact of utilising electronic medical records for clinical research recruitment
Journal Article
Lai, Y. S., & Afseth, J. D. (2019)
A review of the impact of utilising electronic medical records for clinical research recruitment. Clinical Trials, 16(2), 194-203. https://doi.org/10.1177/1740774519829709
Introduction:
Recruitment is an important aspect of clinical research, as poor recruitment could undermine the scientific value of a trial or delay the development process of ...
Best supportive care in advanced lung cancer—more than a label?
Journal Article
Bowden, J., Fenning, S., Marron, B., Macpherson, C., Boyce, S., Wardrope, V., …Johnston, L. (2018)
Best supportive care in advanced lung cancer—more than a label?. BMJ, 363, k5017. https://doi.org/10.1136/bmj.k5017
We should be accountable for delivering the right care in the right place for people nearing the end of life, say Jo Bowden and colleagues.
Holistic needs assessment in brain cancer patients: A systematic review of available tools
Journal Article
Afseth, J., Neubeck, L., Karatzias, T., & Grant, R. (2019)
Holistic needs assessment in brain cancer patients: A systematic review of available tools. European Journal of Cancer Care, 28(3), https://doi.org/10.1111/ecc.12931
This systematic review describes tools which could be considered for use for holistic needs assessment in Brain Cancer. MEDLINE, Cumulative Index to Nursing and Allied Health ...
Proactive community support tailored to holistic needs: A cohort study
Journal Article
Snowden, A., Young, J., & Savinc, J. (2018)
Proactive community support tailored to holistic needs: A cohort study. Cancer Medicine, 7(9), 4836-4845. https://doi.org/10.1002/cam4.1709
Background:
It is increasingly internationally recognised that a cancer diagnosis impacts on people practically and financially as well as physically and psychologically. It ...
Exploring male identity in non-professional carers of someone with cancer: preliminary analysis
Presentation / Conference
Young, J., Snowden, A., Stenhouse, R., & Kyle, R. (2018, March)
Exploring male identity in non-professional carers of someone with cancer: preliminary analysis. Poster presented at British Psych-Oncology Society Annual Conference
Background
Across the world the majority of home‐based care for ill family members is carried out by women. Consequently, research in this field has predominately focused on ...
The role of social context in symptom appraisal and help-seeking among people with lung or colorectal symptoms: A qualitative interview study
Journal Article
Dobson, C., Russell, A., Brown, S., & Rubin, G. (2018)
The role of social context in symptom appraisal and help-seeking among people with lung or colorectal symptoms: A qualitative interview study. European Journal of Cancer Care, 27(2), https://doi.org/10.1111/ecc.12815
Prolonged diagnostic intervals are associated with poorer outcomes, and the patient interval appears to be a substantial contributor to the overall length of the diagnostic in...