Research Output

The effectiveness of home versus community-based weight control programmes initiated soon after breast cancer diagnosis: a randomised controlled trial

  Background
Breast cancer diagnosis may be a teachable moment for lifestyle behaviour change and to prevent adjuvant therapy associated weight gain. We assessed the acceptability and effectiveness of two weight control programmes initiated soon after breast cancer diagnosis to reduce weight amongst overweight or obese women and prevent gains in normal-weight women.

Methods
Overweight or obese (n = 243) and normal weight (n = 166) women were randomised to a three-month unsupervised home (home), a supervised community weight control programme (community) or to standard written advice (control). Primary end points were change in weight and body fat at 12 months. Secondary end points included change in insulin, cardiovascular risk markers, quality of life and cost-effectiveness of the programmes.

Results
Forty-three percent of eligible women were recruited. Both programmes reduced weight and body fat: home vs. control mean (95% CI); weight −2.3 (−3.5, −1.0) kg, body fat −1.6 (−2.6, −0.7) kg, community vs. control; weight −2.4 (−3.6, −1.1) kg, body fat −1.4 (−2.4, −0.5) kg (all p < 0.001). The community group increased physical activity, reduced insulin, cardiovascular disease risk markers, increased QOL and was cost-effective.

Conclusions
The programmes were equally effective for weight control, but the community programme had additional benefits.

Clinical trial registration
ISRCTN68576140

  • Type:

    Article

  • Date:

    01 August 2019

  • Publication Status:

    Published

  • Publisher

    Springer Science and Business Media LLC

  • DOI:

    10.1038/s41416-019-0522-6

  • Cross Ref:

    522

  • ISSN:

    0007-0920

  • Library of Congress:

    RA0421 Public health. Hygiene. Preventive Medicine

  • Dewey Decimal Classification:

    610 Medicine & health

  • Projects:

    NIHR RFPB (PB-PG-0407-12313)

  • Funders:

    National Institute for Health Research

Citation

Harvie, M., Pegington, M., McMullan, D., Bundred, N., Livingstone, K., Campbell, A., …Howell, A. (2019). The effectiveness of home versus community-based weight control programmes initiated soon after breast cancer diagnosis: a randomised controlled trial. British Journal of Cancer, https://doi.org/10.1038/s41416-019-0522-6

Authors

Keywords

weight control; breast cancer diagnosis; home programme; community programme

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