David Hamilton

david hamilton

Dr David Hamilton

Lecturer

Biography

David is a lecturer in physiotherapy and the academic lead for knowledge exchange and innovation for the School of Health and Social Care at Edinburgh Napier University.

He is an active researcher with honorary fellowships at the University of Edinburgh (linked to clinical trials running in NHS Lothian), and at the University of Aberdeen (where he collaborates with the epidemiology group on osteoarthritis and pain research). He was previously a Postdoctoral Researcher and then Fellow and Principle Investigator at the University of Edinburgh over a 10-year period and has collaborated on >£5 million of research grant funding from Versus Arthritis, EPSRC, NIHR and industry partners which has resulted in >90 publications to date.

His primary research interests are in measuring patient outcomes/physical function in osteoarthritis and musculoskeletal injury/disease, orthopaedic/rehabilitative interventions, predictive modelling, evaluating the psychometric properties of outcome questionnaires, and more generally in research methodology and clinical trials. Wider interests transcend musculoskeletal sciences and rehabilitation, from muscle stem cells and regeneration to kinematics and biomechanics.

Recently completed studies include the TRIMAX RCT which was a substantial longitudinal project over 10-years that evaluated whether patients achieved different outcomes with different types of knee replacement prostheses (https://pubmed.ncbi.nlm.nih.gov/32228078/), and the TRIO RCT, which was a major UK national trial evaluating whether physiotherapy targeted to patients predicted to perform poorly following total knee replacement could improve outcomes (https://pubmed.ncbi.nlm.nih.gov/33051212/).

He is currently leading the ROBOTA project at Spire Murrayfield hospital, a novel study evaluating patient outcomes following robotic-assisted hip and knee replacement, and leads the rehabilitation arm of the NIHR funded MOTION RCT with project partners in Edinburgh, Glasgow and Warwick. This major UK national trial is looking at whether joint realignment surgery outperforms active physiotherapy management in young patients with knee osteoarthritis; recruitment is planned to open in early 2023. Further active projects include a suite of clinical studies in hip and knee replacement with friends and partners at Edinburgh orthopaedics: the CASINO RCT (https://pubmed.ncbi.nlm.nih.gov/29661229/), and NEPTUNE and LITTLE RASCAL cohorts.

Alongside Edinburgh and Aberdeen, David has active research collaborations with colleagues at Cardiff University (wearable technology to assess pain), the University of Zurich and the Medical University of Innsbruck (novel patient reported outcomes and methodological research), and at Oxford University and the Virginia Commonwealth University (rehabilitation trials methodology and predictive modelling).

He sits on the Scotland hub of the Council for Allied Health Professions Research, the executive committee (as treasurer) of the British Orthopaedic Research Society, and is part of the EPSRC Osteoarthritis Technology network. For a number of years he has been associate journal editor for BMC musculoskeletal disorders.

David leads the research methodology and dissertation modules for the Physiotherapy, Occupation Therapy and Social Work MSc (pre-reg) programs. He supports a number of PhD and MRes students and is developing allied health postgraduate research at Edinburgh Napier, with a number of clinically qualified colleagues starting their research journeys in 2022. He is always interesting in PhD supervision and can be contacted directly as to this.

Esteem

Advisory panels and expert committees or witness

  • Expert committee: PORTER study – defining poor response to TKA (Dutch Arthroplasty Project)
  • Expert committee: RUBICON-D study - corticosteroid injections for osteoarthritis– University of Bristol NIHR-HTA
  • Expert committee: INFORM guidelines - revision surgery for prosthetic hip infection, University of Bristol - NIHR
  • Executive committee (Treasurer): British Orthopaedic Research Society
  • Co-lead: Scotland group (SE Scotland hub) Council for Allied Health Professional Research
  • Expert working group: ‘Developing OA technologies’ EPSRC OA Technology network, Oswestry
  • Expert working group: ‘Towards prevention of post-traumatic osteoarthritis, Arthritis Research UK, London
  • Expert working group: ‘Conduct of efficacy trials of treatment devices for osteoarthritis', Arthritis Research UK, London
  • Expert working group: 'Harmonising data collection from osteoarthritis studies to enable stratification, Arthritis Research UK, London

 

Conference Organising Activity

  • Session chair, British Orthopaedic Research Society annual meeting (virtual)
  • Organising committee, British Orthopaedic Research Society annual meeting, 2021 (virtual)
  • Local organising and scientific committee: ICORS World Congress of the Orthopaedic Research Societies, Edinburgh 2022
  • Symposium organiser - patient reported outcomes in orthopaedics, European Orthopaedic Research Society, annual meeting, Galway
  • Session chair, Orthopaedic Research Society annual meeting, New Orleans

 

Editorial Activity

  • Editor of special issue: 'the emerging role of technology in the rehabilitation sciences', Frontiers in Digital Health (2020-21)
  • Editorial Board Member: BMC Musculoskeletal Disorders (2017-current)

 

Fellowships and Awards

  • Best poster award (scientific topic group), 'Comparative responsiveness of the PROMIS Global Health questionnaire with the EQ5D-3L in patients undergoing total knee arthroplasty', J Shim, GJ MacFarlane, DF Hamilton, 20th annual EFORT congress, Lisbon
  • Best poster award (scientific topic group), 'Loss of patient function but maintenence of implant derived differences in outcome following TKA:8-year longitudinal follow-up of a prospective RCT', DF Hamilton, R Burnett, JT Patton, GJ Macphearson, AHRW Simpson, P Gaston, 20th annual EFORT congress, Lisbon
  • Young Investigator Award: European Orthopaedic Research Society
  • Force and Motion Foundation travel award: Orthopaedic Research Society, New Orleans
  • Best poster award (scientific topic group) DF Hamilton, P Simpson, JT Patton, CR Howie, R Burnett, 'Patient function following revision TKA with semi-constrained prostheses is equivalent to that following primary TKA: a longitudinal cohort study', 17th annual EFORT congress, Geneva
  • Finalist: Scopus/Elsevier Young Researcher of the Year - UK

 

Grant Reviewer

  • grant reviewer (NIHR, 2021)
  • grant reviewer (MRC, 2020)
  • grant reviewer (EPSRC, 2020)
  • grant reviewer (EPSRC, 2019)
  • grant reviewer (Versus Arthritis, 2019)
  • grant reviewer (Versus Arthritis, 2018)
  • grant reviewer (Versus Arthritis, 2018)
  • grant reviewer (NIHR, 2017)
  • grant reviewer (Versus Arthritis, 2017)

 

Invited Speaker

  • 'Interdisciplinary views of patient reported outcome assessment for postoperative pain: the physiotherapists perspective,' European Society of Anaesthesiology and Intensive Care, annual meeting, Milan
  • 'Non-operative management of osteoarthritis prior to joint replacement', NHS Lothian arthroplasty practitioner training day, Scottish Borders
  • 'Dealing with data in observational studies', Bone and Joint Journal symposium, British Orthopaedic Association annual meeting, Liverpool
  • 'What is the role of physiotherapy in knee replacement?' NHS Research Scotland, Edinburgh
  • 'Evaluating and interpreting cohort studies', Bone and Joint Journal symposium, European Federation of National Associations of Orthopaedics and Traumatology (EFORT) annual meeting, Lisbon
  • 'The future use of patient reported outcomes', Orthopaedic Research Society annual meeting, New Orleans
  • 'Targeting rehabilitation following total joint replacement', Edinburgh musculoskeletal group winter symposium, Edinburgh
  • 'Targeted Rehabilitation to Improve Outcome', Edinburgh Clinical Trials Unit seminar, Edinburgh
  • 'The role of physiotherapy in joint replacement', European Orthopaedic Research Society annual meeting, Galway
  • 'Knee arthroplasty implant trials', The Sheffield Knee Meeting, Sheffield
  • 'Outcomes of revision joint replacement', Stryker Europe AGM, Edinburgh
  • 'Assessing joint replacement outcomes', Stryker Europe AGM, Prague
  • 'Comorbidity and joint replacement outcomes', Arthritis Research UK OA clinical study group, London
  • 'Assessing and measuring clinical outcomes', Stryker International Implant Design Council, New York
  • 'Rugby spinal injuries and assessment', Spine Nation Conference, Edinburgh
  • 'Functional profiling of the cervical spine', International Rugby Board Medical Commission annual meeting, Dublin
  • Faculty: Triathlon TS and revision course (recurrent event), Royal Collage of Surgeons (Edinburgh)
  • Conference presentations: regular presenter with >120 podium and poster presentations at national and international conferences including regular output at the annual meetings of the British Orthopaedic Research Society, European Orthopaedic Research Society, Orthopaedic Research Society, British Orthopaedic Association, European Federation of Orthopaedics and Traumatology, American Academy of Orthopaedic Surgeons, and Chartered Society of Physiotherapy amongst various others

 

Membership of Professional Body

  • Heath & Care Professions Council
  • Chartered Society of Physiotherapists

 

Research Degree External Examining

  • External examining (PhD, University of Edinburgh, 2021)
  • External examining (PhD, Glasgow Caledonian University, 2020)
  • External examining (PhD, Salford University, 2019)

 

Reviewing

  • Journal reviewer: Rheumatology
  • Journal reviewer: Trials
  • Journal reviewer: BMC Musculoskeletal Disorders
  • Journal reviewer: Bone and Joint Research
  • Journal reviewer: BMJ open
  • Journal reviewer: Clinical Orthopaedics and Related Research
  • Journal reviewer: Bone and Joint Journal
  • Journal Reviewer: Ad-hoc reviewer for a variety of journals including: Arthritis Care and Research, Annals of the Rheumatic Diseases, Disability and Rehabilitation, The Knee, PlosOne, Sports Medicine and the New England Journal of Medicine (see Publons Profile)

 

Visiting Positions

  • Hon Research Fellow (Epidemiology), University of Aberdeen
  • Hon Research Fellow, Collage of Medicine (Orthopaedics), University of Edinburgh

 

Date


93 results

Functional outcomes and return to sport following anterior cruciate ligament reconstruction in recreational athletes: A systematic review

Journal Article
Brzeszczynski, F., Turnbull, K., McClelland, C., MacDonald, D., Lawson, G., & Hamilton, D. (2022)
Functional outcomes and return to sport following anterior cruciate ligament reconstruction in recreational athletes: A systematic review. The Knee, 36, 103-113. https://doi.org/10.1016/j.knee.2022.04.005
Introduction Outcomes of anterior cruciate ligament reconstruction (ACLR) are well reported in athletic populations, however surprisingly little information is available for t...

Pre- and intraoperative decision-making challenges in hip arthroscopy for femeroacetabular impingement

Journal Article
Martin, H., Robinson, P., Maempel, J., Hamilton, D., Gaston, P., Safran, M., & Murray, I. (2022)
Pre- and intraoperative decision-making challenges in hip arthroscopy for femeroacetabular impingement. Bone and Joint Journal, 104-B(5), https://doi.org/10.1302/0301-620X.104B5.BJJ-2021-1553.R1
There has been a marked increase in the number of hip arthroscopies performed over the past 16 years, primarily in the management of femoroacetabular impingement (FAI). Insigh...

The effect of sarcopenia on outcomes following orthopaedic surgery: a systematic review

Journal Article
Brzeszczynski, F., Brzeszczynska, J., Duckworth, A. D., Murray, I. R., Simpson, A. H. R. W., & Hamilton, D. F. (2022)
The effect of sarcopenia on outcomes following orthopaedic surgery: a systematic review. Bone and Joint Journal, 104-B(3), 321-330. https://doi.org/10.1302/0301-620x.104b3.bjj-2021-1052.r1
Aims Sarcopenia is characterized by a generalized progressive loss of skeletal muscle mass, strength, and physical performance. This systematic review primarily evaluated the ...

A Cost-Utility Analysis of Robotic Arm-Assisted Total Hip Arthroplasty: Using Robotic Data from the Private Sector and Manual Data from the National Health Service

Journal Article
Clement, N. D., Gaston, P., Hamilton, D. F., Bell, A., Simpson, P., Macpherson, G. J., & Patton, J. T. (2022)
A Cost-Utility Analysis of Robotic Arm-Assisted Total Hip Arthroplasty: Using Robotic Data from the Private Sector and Manual Data from the National Health Service. Advances in orthopedics, 2022, https://doi.org/10.1155/2022/5962260
Purpose. The aim was to assess the cost-effectiveness of robotic arm-assisted total hip arthroplasty (rTHA) compared with manual total hip arthroplasty (mTHA) and to assess th...

The effect of sarcopenia on outcomes following orthopedic surgery: a systematic review

Journal Article
Brzeszczynski, W., Brzeszczynska, J., Duckworth, A., Murray, I., Simpson, H., & Hamilton, D. (2021)
The effect of sarcopenia on outcomes following orthopedic surgery: a systematic review. Bone and Joint Journal, 103B(Supp_16),

Preoperative morbidity and joint awareness while awaiting hip arthroscopy for femoroacetabular impingement

Journal Article
Robinson, P., Williamson, T., Maempel, J., Murray, I., MacDonald, D., Hamilton, D., & Gaston, P. (2021)
Preoperative morbidity and joint awareness while awaiting hip arthroscopy for femoroacetabular impingement. Journal of Experimental Orthopaedics, 8, https://doi.org/10.1186/s40634-021-00431-1
Purpose The Forgotten Joint Score (FJS-12) is a valid tool in the evaluation of patients undergoing hip arthroscopy, assessing the unique concept of joint awareness in the set...

Do the outcomes of hip arthroscopy for femoroacetabular impingement change over time?

Journal Article
Robinson, P., Liu, H., Wilkinson, T., Maempel, J., Murray, I., MacDonald, D., …Gaston, P. (in press)
Do the outcomes of hip arthroscopy for femoroacetabular impingement change over time?. Orthopaedics and Traumatology: Surgery and Research, https://doi.org/10.1016/j.otsr.2021.103157
Background: The purpose of this study was to search for changes in functional outcomes of patients undergoing hip arthroscopy for femoroacetabular impingement (FAI) between sh...

Cross-Validation of Good versus Poor Self-reported Outcome Trajectory Types Following Knee Arthroplasty

Journal Article
Riddle, D., MacFarlane, G., Hamilton, D., Beasley, M., & Dumenci, L. (2022)
Cross-Validation of Good versus Poor Self-reported Outcome Trajectory Types Following Knee Arthroplasty. Osteoarthritis and Cartilage, 30(1), 61-68. https://doi.org/10.1016/j.joca.2021.09.004
Objective To determine whether good versus poor outcome trajectories and predictors of poor outcome obtained in a derivation study could be replicated in an independent sample...

Defining the Patient Acceptable Symptom State Using the Forgotten Joint Score 12 After Hip Arthroscopy

Journal Article
Robinson, P. G., Gaston, P., Williamson, T. R., Murray, I. R., Maempel, J. F., Rankin, C. S., …Hamilton, D. F. (2021)
Defining the Patient Acceptable Symptom State Using the Forgotten Joint Score 12 After Hip Arthroscopy. Arthroscopy, Sports Medicine, and Rehabilitation, 3(6), e1705-e1712. https://doi.org/10.1016/j.asmr.2021.07.027
Purpose To contextualize the Forgotten Joint Score (FJS-12) by identifying a patient acceptable symptomatic state (PASS) threshold for patients undergoing hip arthroscopy and ...

CORR Insights®: Can the Knee Outcome and Osteoarthritis Score (KOOS) Function Subscale Be Linked to the PROMIS Physical Function to Crosswalk Equivalent Scores

Journal Article
Hamilton, D. (2021)
CORR Insights®: Can the Knee Outcome and Osteoarthritis Score (KOOS) Function Subscale Be Linked to the PROMIS Physical Function to Crosswalk Equivalent Scores. Clinical Orthopaedics and Related Research, 479(12), 2665-2666. https://doi.org/10.1097/CORR.0000000000001935

Pre-Napier Funded Projects

  • Research grant: High Tibial Osteotomy versus optimised non-operative care for the management of knee osteoarthritis (MOTION RCT), A Amin, C Scott, DF Hamilton, ND Clement, A Duckworth, S Lewis, J Norrie, A Metcalfe, M Blythe; NIHR HTA , £1.8m
  • Research grant: developing wearable technology to measure nociception "We don't care about pain scores" DJ Mason, DF Hamilton, CA Holt, EPSRC/OATech+ network £62,000 (£15,000 with £47,000 extension)
  • Research grant: Osteoarthritis lifestyle interventions scoping review. R Jones and DF Hamilton. EPSRC/OATech+ network, £36,000
  • Research grant: Stability of implantable trabecular metal metaphyseal cones in bone of varying quality in revision knee surgery. P Pankaj, DF Hamilton, R Burnett, EPSRC, £101,023
  • Research grant: ROBotic-assisted Outcomes of Total joint Arthroplasty (ROBOTA), DF Hamilton, P Gaston, JT Patton. Stryker, £122,115
  • Research grant: Osteoarthritis Preoperative Package for care of Orthotics, Rehabilitation, Topical and oral agent Usage and Nutrition to Improve ouTcomes at a Year (OPPORTUNITY), AHRW Simpson, CR Howie, DF Hamilton, C Tuck, G Murray, S Simpson, C Hankey P Craig, S Kingsbury, P Conaghan, Arthritis Research UK, £220,676
  • Research grant: Can Arthroplasty Stem INfluence Outcome (CASINO RCT), P Gaston, DF Hamilton, AHRW Simpson; Stryker, £279,734
  • Research grant: Targeted Rehabilitation to Improve Outcome following total knee replacement (TRIO RCT). AHRW Simpson, DF Hamilton, G Murray, K Barker, D Beard, G MacFarlane, J Hutchison, T Wilton. Arthritis Research UK, £872,290
  • Research grant: Outcomes of revision total knee replacement, R Burnett, DF Hamilton, CR Howie, AHRW Simpson; Stryker, £267,000

Current Post Grad projects

Non-Napier PhD or MSc by Research supervisions

  • MSc by research supervision: Emma Moon (University of Edinburgh, 2020)
  • MSc by research supervision: Patrick Robinson (University of Edinburgh, 2020)
  • PhD supervision: Alexandria Sehgal (University of Edinburgh, 2022)
  • MSc by research supervision: Rachel Penman (University of Edinburgh, 2019)
  • PhD supervision: Maurice Griffin (University of Edinburgh, 2019)