Characterisation of autophagy induction by the thiopurine drugs azathioprine, mercaptopurine and thioguanine in THP-1 macrophages
Journal Article
Masson, C. D., Findlay-Greene, F., Sousa, F. H., Henderson, P., Fraser, J. A., Barlow, P. G., & Stevens, C. (2025)
Characterisation of autophagy induction by the thiopurine drugs azathioprine, mercaptopurine and thioguanine in THP-1 macrophages. Naunyn-Schmiedeberg's Archives of Pharmacology, 398(4), 4467-4478. https://doi.org/10.1007/s00210-024-03563-0
Activating autophagy may be therapeutically beneficial, and we have previously shown that azathioprine (AZA), an immunomodulatory drug, induces autophagy. Here, we evaluated t...