Brown, D. M., Hutchison, L., Donaldson, K. & Stone, V. (2007). The effects of PM10 particles and oxidative stress on macrophages and lung epithelial cells: modulating effects of calcium-signaling antagonists. American journal of physiology. Lung cellular and molecular physiology. 292, L1444-L1451. doi:10.1152/ajplung.00162.2006. ISSN 1522-1504
We have previously examined the ability of air pollution particles (PM10) to promote release of the proinflammatory cytokine tumor necrosis factor- (TNF-) from human periphera...
Brown, D. M., Hutchison, L., Donaldson, K., MacKenzie, S., Dick, C. & Stone, V. (2007). The effect of oxidative stress on macrophages and lung epithelial cells: the role of phosphodiesterases 1 and 4. Toxicology Letters. 168, 1-6. doi:10.1016/j.toxlet.2006.10.016. ISSN 0378-4274
Reactive oxygen species (ROS) have been implicated in various pulmonary diseases by causing direct injury to lung epithelial cells. Signalling activity of cells through transc...