Mark Ross

Biography

I graduated from my undergraduate B.Sc with Honours in Sport and Exercise Science at Heriot Watt University in 2009 where I was awarded a first class degree and the James Watt Medal for distinction in the programme. I went on to study a M.Sc by Research at the Waterford Institute of Technology, where I investigated the effects of aerobic and resistance exercise on circulating angiogenic cells, which repair and stimulate the growth of blood vessels. Subsequently, I went on to complete my Ph.D in Exercise Physiology at Edinburgh Napier University investigating how ageing and exercise affect these circulating angiogenic cells, with focus also on cell surface receptor expression.

I am a Lecturer in Exercise Physiology at Edinburgh Napier University, where I teach on Introduction to Exercise Physiology, Current Issues in Sporting Performance (both UG year 2) and Advanced Exercise Physiology (UG year 4) as well as on the M.Sc programme in Sports Performance Enhancement and the M.Sc in Clinical Exercise Science. I am also a British Association of Sport and Exercise Sciences (BASES) accredited Sport and Exercise Scientist (Physiology Support and Research), with previous work in Rugby Union, Football, Golf, Endurance Sports, Track Cycling, and Rowing. In addition, I am also an accredited UK Anti-Doping Advisor (UKAD) and a member of the BASES Public and External Affairs Advisory Panel.

My research interests lie in vascular health, age and exercise, with specific focus on circulating cells in the blood which stimulate vascular regeneration and repair. I am currently working to quantify the bone marrow-derived stem cell response to acute and chronic exercise in both young and older adults, as well as potential interventions to maximise the stem cell response in older individuals.

Our most recent work has been investigating how exercise may counteract the negative side-effects of chemotherapy on blood vessels of breast cancer patients.

Accepting M.Sc by Research and Ph.D students.

Themes

Esteem

Advisory panels and expert committees or witness

  • BASES Public and External Affairs Advisory Panel
  • COST VascAgeNet
  • BASES COVID-19 Steering Group

 

Conference Organising Activity

  • Ross M, Muggeridge D, & Dodd J. (2021). Moderate and vigorous physical activity levels are associated with circulating CD34+ progenitor cells which are predictive of all-cause and cardiovascular mortality. European Society of Cardiology- Preventative Cardiology 2021.
  • Taylor GS, Smith K, Scragg J, Bashir A, Flatt A, Stevenson E, McDonald TJ, Oram RA, Shaw JA, Ross M, & West DJ. (2020). 680-P: Residual ß-Cell Function in Long-Term Type 1 Diabetes Is Associated with a Fivefold Greater Mobilization of Endothelial Progenitor Cells after Exercise. Diabetes, 69, 680-P.
  • Taylor GS, Smith K, Scragg J, Bashir A, Flatt A, Stevenson E, McDonald TJ, Oram RA, Shaw JA, Ross M, & West DJ. (2020). 679-P: Endothelial and Hematopoietic Progenitor Cells Are Reduced at Rest and Have an Attenuated Mobilization Response to Exercise in People with Type 1 Diabetes. Diabetes, 69, 679-P.
  • Taylor GS, Ross M, Okwose NC, Cappter T, Bashir A, Shaw JA, Stevenson EJ & West DJ. (2019). Plasma volume changes with exercise in the postprandial state and its influence on the count of rare circulating angiogenic cells in individuals with Type 1 diabetes. Diabetic Medicine, P114, 36, S1, 72-72.
  • Muggeridge D, Rae M, Florida-James G & Ross M. (2018). Physical Activity Index influence on all-cause mortality and vascular health measures. Findings from the Framingham Heart Study. European College of Sports Science, Dublin, July 2018.
  • Invited Speaker- Exercise, shear, and endothelial progenitor cells, World Congress of Microcirculation, Vancouver, 2018)
  • Ross M. (2018). Exercise stimulates a preferential increase in senescent-associated CD28null angiogenic T-cells in older, but not younger men. European College of Sports Science, Dublin, July 2018.
  • Ross M, Ingram L, Cranston I, Taylor G, West D, Wright G, Chambers G, Simpson R & Florida-James G. (2017). Acute Exercise-induced Angiogenic T Cell Redistribution Is Attenuated in Older Men. ACSM 2017
  • Smith K & Ross M. (2016). The effect of an acute dose of inorganic dietary nitrate on intermittent sport-related performance in the heat. International Sport, Exercise and Nutrition Conference 2017 (ISENC 2017), Newcastle, England. December 2017.
  • Ross M, Malone E, Simpson RJ & Florida-James G. (2016). High cardiorespiratory fitness alleviates the negative impact of increasing sitting time on CD31+ T-cell number. ACSM 2016

 

Editorial Activity

  • Associate Review Editor for Frontiers in Physiology
  • Invited Guest Editor- Current Cardiology Reviews- The Ageing Cardiovascular System- Influence of Lifestyle Modifications’

 

External Examining/Validations

  • Validation of MSc Clinical Exercise Physiology and Newcastle University

 

Fellowships and Awards

  • Young Investigator Award Nominee- European Society of Cardiology
  • Best Lecturer- School of Applied Sciences
  • Fellow of the Higher Education Academy
  • Fellow of the Higher Education Academy
  • BASES Accredited Sport and Exercise Scientist

 

Grant Reviewer

  • Dutch Research Council
  • National Centre for the Replacement, Refinement and Reductions of Animals in Research (NC3R)
  • NHS Liverpool Clinical Commissioning Group (CCG)

 

Invited Speaker

  • Invited Keynote for Clinical Exercise Physiologists Association
  • Invited Speaker at the World Congress of Microcirculation

 

Membership of Professional Body

  • Professional Member of Physiological Society
  • Accredited Sport and Exercise Scientist with BASES
  • Chartered Scientist
  • Professional Member of the British Association of Sport and Exercise Sciences (BASES)

 

Research Degree External Examining

  • MPhil 2019- LJMU Daniel Bannell- comparing the effects of exercise with IPC on endothelial ischemia reperfusion injuries

 

Reviewing

  • Atherosclerosis, Thrombosis and Vascular Biology
  • Frontiers in Physiology
  • European Journal of Preventative Cardiology
  • PLOS One
  • Cardiovascular Translational Research
  • Annals of Physical Rehabilitation Medicine
  • Aging and Physical Activity
  • International Journal of Sports Medicine
  • FASEB Journal
  • Journal of Science and Medicine in Sport
  • Stem Cells International
  • Nutrients
  • Applied Physiology, Nutrition and Metabolism
  • Scientific Reports
  • Frontiers in Endocrinology
  • Pediatric Exercise Science
  • Cell Biology International
  • Oxidative Medicine and Cellular Longevity
  • Gerontology
  • Journal of Applied Physiology
  • Journal of Science and Cycling
  • Exercise Immunology Review
  • Experimental Physiology
  • Medicine and Science in Sport and Exercise
  • American Journal of Physiology- Regulatory, Integrative and Comparative Physiology
  • American Journal of Physiology- Heart and Circulatory Physiology

 

Date


29 results

Spontaneous coronary artery dissection: a systematic review of physical and psychosocial recovery following discharge from hospital

Journal Article
Neubeck, L., McHale, S., Ross, M., MacGillvray, S., Galbraith, M., & Hanson, C. (in press)
Spontaneous coronary artery dissection: a systematic review of physical and psychosocial recovery following discharge from hospital. European Journal of Cardiovascular Nursing, https://doi.org/10.1093/eurjcn/zvac009
Introduction Spontaneous coronary artery dissection (SCAD) is increasingly recognised as an important cause of myocardial infarction, particularly among women. SCAD survivors ...

Type 1 diabetes patients with different residual beta-cell function but similar age, HBA1c, and cardiorespiratory fitness have differing exercise-induced angiogenic cell mobilisation

Journal Article
Taylor, G. S., Shaw, A., Scragg, J. H., Smith, K., Campbell, M. D., Mcdonald, T. J., …West, D. J. (2022)
Type 1 diabetes patients with different residual beta-cell function but similar age, HBA1c, and cardiorespiratory fitness have differing exercise-induced angiogenic cell mobilisation. Frontiers in Endocrinology, 13, https://doi.org/10.3389/fendo.2022.797438
Background: Many individuals with type 1 diabetes retain residual beta-cell function. Sustained endogenous insulin and C-peptide secretion is associated with reduced diabetes ...

Breast cancer chemotherapy vascular toxicity: A review of mediating mechanisms and exercise as a potential therapeutic

Journal Article
Mclaughlin, M., Florida-James, G., & Ross, M. (2021)
Breast cancer chemotherapy vascular toxicity: A review of mediating mechanisms and exercise as a potential therapeutic. Vascular Biology, 3(1), R106-R120. https://doi.org/10.1530/VB-21-0013
Breast cancer chemotherapy, although very potent against tumour tissue, results in significant cardiovascular toxicity. The focus of research in this area has been predominant...

Type 1 diabetes patients increase CXCR4+ and CXCR7+ haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated

Journal Article
Taylor, G. S., Shaw, A., Smith, K., Capper, T. E., Scragg, J. H., Cronin, M., …West, D. J. (2021)
Type 1 diabetes patients increase CXCR4+ and CXCR7+ haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated. Scientific Reports, 11, https://doi.org/10.1038/s41598-021-93886-2
Background: Exercise mobilizes angiogenic cells, which stimulate vascular repair. However, limited research suggests exercise-induced increase of endothelial progenitor cell (...

CD34+ progenitors are predictive of mortality and are associated with physical activity in cardiovascular disease patients

Journal Article
Muggeridge, D., Dodd, J., & Ross, M. D. (2021)
CD34+ progenitors are predictive of mortality and are associated with physical activity in cardiovascular disease patients. Atherosclerosis, 333, 108-115. https://doi.org/10.1016/j.atherosclerosis.2021.07.004
Background and aims Circulating progenitor cells (CPCs) play an important role in vascular repair and can influence cardiovascular (CV) health and longevity. Exercise is known...

Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age

Journal Article
Lithgow, H., Florida‐James, G., Ross, M., Duncan, G., & Leggate, M. (2021)
Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age. Experimental Physiology, 106(7), 1460-1469. https://doi.org/10.1113/ep089480
Vitamin D plays a key role in the modulation of the immune system, mediated through the intracellular vitamin D receptor (VDR). Exercise has been shown to influence the activi...

The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system

Journal Article
Ellison-Hughes, G. M., Colley, L., O'Brien, K. A., Roberts, K. A., Agbaedeng, T. A., & Ross, M. (2020)
The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system. Frontiers in Cardiovascular Medicine, 7, https://doi.org/10.3389/fcvm.2020.602183
The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has led to 47m infected cases and 1.2m (2.6...

Vascular Manifestations of COVID-19 -Thromboembolism and Microvascular Dysfunction

Journal Article
Roberts, K. A., Colley, L., Agbaedeng, T. A., Ellison-Hughes, G. M., & Ross, M. D. (2020)
Vascular Manifestations of COVID-19 -Thromboembolism and Microvascular Dysfunction. Frontiers in Cardiovascular Medicine, 7, https://doi.org/10.3389/fcvm.2020.598400
The coronavirus pandemic has reportedly infected over 22 million individuals and caused over 778,000 deaths worldwide. This novel coronavirus, officially named severe acute re...

The effect of exercise intensity and duration on cardiac troponin release

Journal Article
Mills, N., Marshall, L., Lee, K. K., Stewart, S., Wild, A., Fujisawa, T., …Ross, M. (2020)
The effect of exercise intensity and duration on cardiac troponin release. Circulation, 141(1), 83-85. https://doi.org/10.1161/CIRCULATIONAHA.119.041874
Abstract not available.

Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men.

Journal Article
Montgomery, R., Paterson, A., Williamson, C., Florida-James, G., & Ross, M. D. (2019)
Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men. Frontiers in Physiology, https://doi.org/10.3389/fphys.2019.00447
Endothelial progenitor cells (EPCs) are a vasculogenic subset of progenitors, which play a key role in maintenance of endothelial integrity. These cells are exercise-responsiv...

Current Post Grad projects

Previous Post Grad projects

Non-Napier PhD or MSc by Research supervisions

  • Dr Guy Taylor-The influence of beta cell function on resting and activity-induced endothelial and haematopoietic stem cell mobilisation in type 1 diabetics- Completed