Mark Ross

Biography

I graduated from my undergraduate B.Sc with Honours in Sport and Exercise Science at Heriot Watt University in 2009 where I was awarded a first class degree and the James Watt Medal for distinction in the programme. I went on to study a M.Sc by Research at the Waterford Institute of Technology, where I investigated the effects of aerobic and resistance exercise on circulating angiogenic cells, which repair and stimulate the growth of blood vessels. Subsequently, I went on to complete my Ph.D in Exercise Physiology at Edinburgh Napier University investigating how ageing and exercise affect these circulating angiogenic cells, with focus also on cell surface receptor expression.

I am a Lecturer in Exercise Physiology at Edinburgh Napier University, where I teach on Introduction to Exercise Physiology, Current Issues in Sporting Performance (both UG year 2) and Advanced Exercise Physiology (UG year 4) as well as on the M.Sc programme in Sports Performance Enhancement and the M.Sc in Clinical Exercise Science. I am also a British Association of Sport and Exercise Sciences (BASES) accredited Sport and Exercise Scientist (Physiology Support and Research), with previous work in Rugby Union, Football, Golf, Endurance Sports, Track Cycling, and Rowing. In addition, I am also an accredited UK Anti-Doping Advisor (UKAD) and a member of the BASES Public and External Affairs Advisory Panel.

My research interests lie in vascular health, age and exercise, with specific focus on circulating cells in the blood which stimulate vascular regeneration and repair. I am currently working to quantify the bone marrow-derived stem cell response to acute and chronic exercise in both young and older adults, as well as potential interventions to maximise the stem cell response in older individuals.

Our most recent work has been investigating how exercise may counteract the negative side-effects of chemotherapy on blood vessels of breast cancer patients.

Accepting M.Sc by Research and Ph.D students.

Themes

Esteem

Advisory panels and expert committees or witness

  • COST VascAgeNet
  • BASES Public and External Affairs Advisory Panel
  • BASES COVID-19 Steering Group

 

Conference Activity

  • Ross M, Muggeridge D, & Dodd J. (2021). Moderate and vigorous physical activity levels are associated with circulating CD34+ progenitor cells which are predictive of all-cause and cardiovascular mortality. European Society of Cardiology- Preventative Cardiology 2021.
  • Taylor GS, Smith K, Scragg J, Bashir A, Flatt A, Stevenson E, McDonald TJ, Oram RA, Shaw JA, Ross M, & West DJ. (2020). 680-P: Residual ß-Cell Function in Long-Term Type 1 Diabetes Is Associated with a Fivefold Greater Mobilization of Endothelial Progenitor Cells after Exercise. Diabetes, 69, 680-P.
  • Taylor GS, Smith K, Scragg J, Bashir A, Flatt A, Stevenson E, McDonald TJ, Oram RA, Shaw JA, Ross M, & West DJ. (2020). 679-P: Endothelial and Hematopoietic Progenitor Cells Are Reduced at Rest and Have an Attenuated Mobilization Response to Exercise in People with Type 1 Diabetes. Diabetes, 69, 679-P.
  • Taylor GS, Ross M, Okwose NC, Cappter T, Bashir A, Shaw JA, Stevenson EJ & West DJ. (2019). Plasma volume changes with exercise in the postprandial state and its influence on the count of rare circulating angiogenic cells in individuals with Type 1 diabetes. Diabetic Medicine, P114, 36, S1, 72-72.
  • Invited Speaker- Exercise, shear, and endothelial progenitor cells, World Congress of Microcirculation, Vancouver, 2018)
  • Muggeridge D, Rae M, Florida-James G & Ross M. (2018). Physical Activity Index influence on all-cause mortality and vascular health measures. Findings from the Framingham Heart Study. European College of Sports Science, Dublin, July 2018.
  • Ross M. (2018). Exercise stimulates a preferential increase in senescent-associated CD28null angiogenic T-cells in older, but not younger men. European College of Sports Science, Dublin, July 2018.
  • Ross M, Ingram L, Cranston I, Taylor G, West D, Wright G, Chambers G, Simpson R & Florida-James G. (2017). Acute Exercise-induced Angiogenic T Cell Redistribution Is Attenuated in Older Men. ACSM 2017
  • Smith K & Ross M. (2016). The effect of an acute dose of inorganic dietary nitrate on intermittent sport-related performance in the heat. International Sport, Exercise and Nutrition Conference 2017 (ISENC 2017), Newcastle, England. December 2017.
  • Ross M, Malone E, Simpson RJ & Florida-James G. (2016). High cardiorespiratory fitness alleviates the negative impact of increasing sitting time on CD31+ T-cell number. ACSM 2016

 

Editorial Activity

  • Associate Review Editor for Frontiers in Physiology
  • Invited Guest Editor- Current Cardiology Reviews- The Ageing Cardiovascular System- Influence of Lifestyle Modifications’

 

External Examining/Validations

  • Validation of MSc Clinical Exercise Physiology and Newcastle University

 

Fellowships and Awards

  • Young Investigator Award Nominee- European Society of Cardiology
  • Best Lecturer- School of Applied Sciences
  • Fellow of the Higher Education Academy
  • Fellow of the Higher Education Academy
  • BASES Accredited Sport and Exercise Scientist

 

Grant Reviewer

  • Dutch Research Council
  • National Centre for the Replacement, Refinement and Reductions of Animals in Research (NC3R)
  • NHS Liverpool Clinical Commissioning Group (CCG)

 

Invited Speaker

  • Invited Speaker at the World Congress of Microcirculation

 

Membership of Professional Body

  • Professional Member of Physiological Society
  • Accredited Sport and Exercise Scientist with BASES
  • Professional Member of the British Association of Sport and Exercise Sciences (BASES)
  • Chartered Scientist

 

Research Degree External Examining

  • MPhil 2019- LJMU Daniel Bannell- comparing the effects of exercise with IPC on endothelial ischemia reperfusion injuries

 

Reviewing

  • Atherosclerosis, Thrombosis and Vascular Biology
  • Aging and Physical Activity
  • Annals of Physical Rehabilitation Medicine
  • Cardiovascular Translational Research
  • European Journal of Preventative Cardiology
  • Frontiers in Physiology
  • International Journal of Sports Medicine
  • PLOS One
  • Scientific Reports
  • FASEB Journal
  • Applied Physiology, Nutrition and Metabolism
  • Journal of Science and Medicine in Sport
  • Nutrients
  • Stem Cells International
  • Frontiers in Endocrinology
  • Pediatric Exercise Science
  • Cell Biology International
  • Gerontology
  • Oxidative Medicine and Cellular Longevity
  • Exercise Immunology Review
  • Journal of Science and Cycling
  • Journal of Applied Physiology
  • Experimental Physiology
  • Medicine and Science in Sport and Exercise
  • American Journal of Physiology- Heart and Circulatory Physiology
  • American Journal of Physiology- Regulatory, Integrative and Comparative Physiology

 

Date


24 results

Exercise acutely increases vitamin D receptor (VDR) expression in T-lymphocytes in vitamin D deficient men, independent of age

Journal Article
Florida-James, G., Leggate, M., Duncan, G., Ross, M., & Lithgow, H. (in press)
Exercise acutely increases vitamin D receptor (VDR) expression in T-lymphocytes in vitamin D deficient men, independent of age. Experimental Physiology, https://doi.org/10.1113/EP089480
Vitamin D plays a key role in the modulation of the immune system, mediated through the intracellular vitamin D receptor (VDR). Exercise has been shown to influence the activi...

The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system

Journal Article
Ellison-Hughes, G. M., Colley, L., O'Brien, K. A., Roberts, K. A., Agbaedeng, T. A., & Ross, M. (2020)
The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system. Frontiers in Cardiovascular Medicine, 7, https://doi.org/10.3389/fcvm.2020.602183
The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has led to 47m infected cases and 1.2m (2.6...

Vascular Manifestations of COVID-19 -Thromboembolism and Microvascular Dysfunction

Journal Article
Roberts, K. A., Colley, L., Agbaedeng, T. A., Ellison-Hughes, G. M., & Ross, M. D. (2020)
Vascular Manifestations of COVID-19 -Thromboembolism and Microvascular Dysfunction. Frontiers in Cardiovascular Medicine, 7, https://doi.org/10.3389/fcvm.2020.598400
The coronavirus pandemic has reportedly infected over 22 million individuals and caused over 778,000 deaths worldwide. This novel coronavirus, officially named severe acute re...

The effect of exercise intensity and duration on cardiac troponin release

Journal Article
Mills, N., Marshall, L., Lee, K. K., Stewart, S., Wild, A., Fujisawa, T., …Ross, M. (2020)
The effect of exercise intensity and duration on cardiac troponin release. Circulation, 141(1), 83-85. https://doi.org/10.1161/CIRCULATIONAHA.119.041874
Abstract not available.

Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men.

Journal Article
Montgomery, R., Paterson, A., Williamson, C., Florida-James, G., & Ross, M. D. (2019)
Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men. Frontiers in Physiology, https://doi.org/10.3389/fphys.2019.00447
Endothelial progenitor cells (EPCs) are a vasculogenic subset of progenitors, which play a key role in maintenance of endothelial integrity. These cells are exercise-responsiv...

Circulating angiogenic cell response to sprint interval and continuous exercise.

Journal Article
O'Carroll, L., Wardrop, B., Murphy, R. P., Ross, M. D., & Harrison, M. (2019)
Circulating angiogenic cell response to sprint interval and continuous exercise. European Journal of Applied Physiology, 119(3), 743-752. https://doi.org/10.1007/s00421-018-04065-7
Although commonly understood as immune cells, certain T lymphocyte and monocyte subsets have angiogenic potential, contributing to blood vessel growth and repair. These cells ...

An acute dose of inorganic dietary nitrate does not improve high-intensity, intermittent exercise performance in temperate or hot and humid conditions

Journal Article
Smith, K., Muggeridge, D. J., Easton, C., & Ross, M. D. (2019)
An acute dose of inorganic dietary nitrate does not improve high-intensity, intermittent exercise performance in temperate or hot and humid conditions. European Journal of Applied Physiology, 119(3), 723-733. https://doi.org/10.1007/s00421-018-04063-9
Purpose: Dietary nitrate (NO3-) has repeatedly been shown to improve endurance and intermittent, high-intensity events in temperate conditions. However, the ergogenic effects...

Endothelial Regenerative Capacity and Aging: Influence of Diet, Exercise and Obesity

Journal Article
Ross, M. D. (2018)
Endothelial Regenerative Capacity and Aging: Influence of Diet, Exercise and Obesity. Current Cardiology Reviews, 14(4), 233-244. doi:10.2174/1573403X14666180726112303
The endothelium plays an important role in cardiovascular regulation, from blood flow, to platelet aggregation, immune cell infiltration and demargination. A dysfunctional end...

Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men

Journal Article
Ross, M., Ingram, L., Taylor, G., Malone, E., Simpson, R. J., West, D., & Florida-James, G. (2018)
Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men. Physiological Reports, 6(12), 1-11. https://doi.org/10.14814/phy2.13697
Aging is associated with elevated cardiovascular disease risk. As a result of aging, endothelial dysfunction develops, partly due to a reduction in vascular regenerative abili...

Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations

Journal Article
Kemp, S., Young, L., Ross, M., Prach, M., Hutchison, G. R., Malone, E., & Fraser, J. A. (2018)
Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations. Scientific Reports, 8(1), https://doi.org/10.1038/s41598-018-25854-2
Neutrophil surveillance is central to nanoparticle clearance. Silver nanoparticles (AgNP) have numerous uses, however conflicting evidence exists as to their impact on neutrop...

Current Post Grad projects

Previous Post Grad projects

Non-Napier PhD or MSc by Research supervisions

  • Dr Guy Taylor-The influence of beta cell function on resting and activity-induced endothelial and haematopoietic stem cell mobilisation in type 1 diabetics- Completed