De Llanos, R., Martínez-Garay, C. A., Fita-Torró, J., Romero, A. M., Martínez-Pastor, M. T., & Puig, S. (2016). Soybean ferritin expression in saccharomyces cerevisiae modulates iron accumulation and resistance to elevated iron concentrations. Applied and Environmental Microbiology, 82, (3052-3060). doi:10.1128/AEM.00305-16. ISSN 0099-2240
Fungi, including the yeast Saccharomyces cerevisiae, lack ferritin and use vacuoles as iron storage organelles. This work explored how plant ferritin expression influenced bak...
Martinez-Garay, C., De Llanos, R., Martinez-Pastor, M. & Puig, S. (2016). Responses of saccharomyces cerevisiae strains from different origins to elevated iron concentrations. Applied and Environmental Microbiology. 82, 1906-1916. doi:10.1128/AEM.03464-15. ISSN 0099-2240
Iron is an essential micronutrient for all eukaryotic organisms. However, the low solubility of ferric iron has tremendously increased the prevalence of iron deficiency anemia...
Sanvisens, N., Romero, A. M., An, X., Zhang, C., de Llanos, R., Martinez-Pastor, M. T., …Puig, S. (2014). Yeast Dun1 Kinase Regulates Ribonucleotide Reductase Inhibitor Sml1 in Response to Iron Deficiency. Molecular and Cellular Biology. 34(17), 3259-3271. doi:10.1128/mcb.00472-14. ISSN 0270-7306
Iron is an essential micronutrient for all eukaryotic organisms because it participates as a redox-active cofactor in many biological processes, including DNA replication and ...
Martínez-Pastor, M., De Llanos, R., Romero, A. & Puig, S. (2013). Post-Transcriptional Regulation of Iron Homeostasis in Saccharomyces cerevisiae. International journal of molecular sciences. 14(8), 15785-15809. doi:10.3390/ijms140815785. ISSN 1422-0067
Iron is an essential micronutrient for all eukaryotic organisms because it participates as a redox cofactor in a wide variety of biological processes. Recent studies in Saccha...
Puig, S., Sanvisens, N. & Llanos, R. D. (2013). Function and Regulation of Yeast Ribonucleotide Reductase: Cell Cycle, Genotoxic Stress, and Iron Bioavailability. Biomedical Journal. 36(2)doi:10.4103/2319‑4170.110398. ISSN 2319-4170
All eukaryotic organisms require an adequate, balanced concentration of deoxyribonucleoside triphosphates (dNTPs) in order to assure accurate DNA replication and repair, and t...
Consejo Superior de Investigaciones Científicas
The main goal of this project is to understand the mechanisms responsible for the virulence of food-related yeasts on humans, and to provide tools and recommendations to prevent the release of yeasts ...