Lecturer in Biological Chemistry
Cameron, A. R., Logie, L., Patel, K., Erhardt, S., Bacon, S., Middleton, P., …Rena, G. (2018). Metformin selectively targets redox control of complex I energy transduction. Redox Biology, 14, 187-197. doi:10.1016/j.redox.2017.08.018
Many guanide-containing drugs are antihyperglycaemic but most exhibit toxicity, to the extent that only the biguanide metformin has enjoyed sustained clinical use. Here, we ha...