Protocols for Understanding the Redox Behavior of Copper-Containing Systems
Journal Article
Malcomson, T., Repiščák, P., Erhardt, S., & Paterson, M. J. (2022)
Protocols for Understanding the Redox Behavior of Copper-Containing Systems. ACS Omega, 7(49), 45057-45066. https://doi.org/10.1021/acsomega.2c05484
Suitability of single-reference density functional theory (DFT) methods for the calculation of redox potentials of copper-containing macrocycle complexes was confirmed by the ...
Metformin selectively targets redox control of complex I energy transduction
Journal Article
Cameron, A. R., Logie, L., Patel, K., Erhardt, S., Bacon, S., Middleton, P., …Rena, G. (2018)
Metformin selectively targets redox control of complex I energy transduction. Redox Biology, 14, 187-197. https://doi.org/10.1016/j.redox.2017.08.018
Many guanide-containing drugs are antihyperglycaemic but most exhibit toxicity, to the extent that only the biguanide metformin has enjoyed sustained clinical use. Here, we ha...