Research Output
A randomized feasibility pilot trial of hearing treatment for reducing cognitive decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study
  Introduction
Hearing loss (HL) is prevalent and independently related to cognitive decline and dementia. There has never been a randomized trial to test if HL treatment could reduce cognitive decline in older adults.

Methods
A 40-person (aged 70–84 years) pilot study in Washington County, MD, was conducted. Participants were randomized 1:1 to a best practices hearing or successful aging intervention and followed for 6 months. clinicaltrials.gov Identifier: NCT02412254.

Results
The Aging and Cognitive Health Evaluation in Elders Pilot (ACHIEVE-P) Study demonstrated feasibility in recruitment, retention, and implementation of interventions with no treatment-related adverse events. A clear efficacy signal of the hearing intervention was observed in perceived hearing handicap (mean of 0.11 to −1.29 standard deviation [SD] units; lower scores better) and memory (mean of −0.10 SD to 0.38 SD).

Discussion
ACHIEVE-P sets the stage for the full-scale ACHIEVE trial (N = 850, recruitment beginning November 2017), the first randomized trial to determine efficacy of a best practices hearing (vs. successful aging) intervention on reducing cognitive decline in older adults with HL.

  • Type:

    Article

  • Date:

    21 June 2017

  • Publication Status:

    Published

  • Publisher

    Wiley

  • DOI:

    10.1016/j.trci.2017.06.003

  • Cross Ref:

    10.1016/j.trci.2017.06.003

  • ISSN:

    2352-8737

  • Funders:

    Eleanor Schwartz Charitable Foundation; National Institute on Aging

Citation

Deal, J. A., Albert, M. S., Arnold, M., Bangdiwala, S. I., Chisolm, T., Davis, S., …Lin, F. R. (2017). A randomized feasibility pilot trial of hearing treatment for reducing cognitive decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 3(3), 410-415. https://doi.org/10.1016/j.trci.2017.06.003

Authors

Keywords

Psychiatry and Mental health; Clinical Neurology

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