Research Output
Exercise for individuals with bone metastases: A systematic review
  Background
Exercise has the potential to improve physical function and quality of life in individuals with bone metastases but is often avoided due to safety concerns. This systematic review summarizes the safety, feasibility and efficacy of exercise in controlled trials that include individuals with bone metastases.

Methods
MEDLINE, Embase, Pubmed, CINAHL, PEDro and CENTRAL databases were searched up to July 16, 2020.

Results
A total of 17 trials were included incorporating aerobic exercise, resistance exercise or soccer interventions. Few (n=4, 0.5%) serious adverse events were attributed to exercise participation, with none related to bone metastases. Mixed efficacy results were found, with exercise eliciting positive changes or no change. The majority of trials included an element of supervised exercise instruction (n=16, 94%) and were delivered by qualified exercise professionals (n=13, 76%).

Conclusions
Exercise appears safe and feasible for individuals with bone metastases when it includes an element of supervised exercise instruction.

  • Type:

    Article

  • Date:

    03 August 2021

  • Publication Status:

    Published

  • DOI:

    10.1016/j.critrevonc.2021.103433

  • Cross Ref:

    10.1016/j.critrevonc.2021.103433

  • ISSN:

    1040-8428

  • Funders:

    Edinburgh Napier Funded; Astellas Pharma Canada

Citation

Weller, S., Hart, N. H., Bolam, K. A., Mansfield, S., Santa Mina, D., Winters-Stone, K. M., …Campbell, K. L. (2021). Exercise for individuals with bone metastases: A systematic review. Critical Reviews in Oncology/Hematology, 166, Article 103433. https://doi.org/10.1016/j.critrevonc.2021.103433

Authors

Keywords

neoplasm metastasis; bone neoplasms; neoplasms; rehabilitation; Exercise; sports; systematic review

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