Edinburgh Napier University

  Ogilvie's syndrome is is an acute intestinal pseudo-obstruction associated with massive dilatation, usually of the colon, but also of the small intestine. Mechanical obstruction is absent, and there is parasympathetic nerve dysfunction. Ogilvie's syndrome affects mainly the caecum and right colon, and can lead to life-threatening spontaneous perforation. The syndrome is attributed to imbalance of the autonomic nervous system, but the pathogenic mechanism remains unknown. This article gives an overview of the normal anatomy and physiology of the large bowel, and examines the aetiology, diagnosis and management of Ogilvie's syndrome. The role of the nurse and midwife in the recognition and management of this potentially life-threatening condition is highlighted.