Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification
Journal Article
Houston, D. A., Staines, K. A., MacRae, V. E., & Farquharson, C. (2016)
Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification. Journal of Visualized Experiments, 118(118), https://doi.org/10.3791/54978
The fundamental process of endochondral ossification is under tight regulation in the healthy individual so as to prevent disturbed development and/or longitudinal bone growth...
Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise
Journal Article
Campbell, J. P., Guy, K., Cosgrove, C., Florida-James, G., & Simpson, R. J. (2008)
Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise. Brain, Behavior, and Immunity, 22(3), 375-380. https://doi.org/10.1016/j.bbi.2007.09.001
Cytotoxic T-lymphocytes co-express the T-cell receptor, CD3 and the MHC I restricted antigen CD8. Although total CD8 expression is often used to identify CD8+ T-cells in blood...
Apoptosis does not contribute to the blood lymphocytopenia observed after intensive and downhill treadmill running in humans.
Journal Article
Simpson, R. J., Florida-James, G., Whyte, G. P., Black, J., Ross, J. & Guy, K. (2007)
Apoptosis does not contribute to the blood lymphocytopenia observed after intensive and downhill treadmill running in humans. Research in Sports Medicine. 15, 157-174. doi:10.1080/15438620701405339. ISSN 1543-8627
The lymphocytopenia that occurs during the recovery stage of exercise may be a result of apoptosis through an increased expression of CD95, a loss of the complement regulatory...
Optimal power-to-mass ratios when predicting flat and hill-climbing time-trial cycling.
Journal Article
Nevill, A. M., Jobson, S. A., Davison, R., & Jeukendrup, A. E. (2007)
Optimal power-to-mass ratios when predicting flat and hill-climbing time-trial cycling. European Journal of Applied Physiology, 97, 424-431. https://doi.org/10.1007/s00421-006-0189-6
The purpose of this article was to establish whether previously reported oxygen-to-mass ratios, used to predict flat and hill-climbing cycling performance, extend to similar p...
The effects of PM10 particles and oxidative stress on macrophages and lung epithelial cells: modulating effects of calcium-signaling antagonists.
Journal Article
Brown, D. M., Hutchison, L., Donaldson, K. & Stone, V. (2007)
The effects of PM10 particles and oxidative stress on macrophages and lung epithelial cells: modulating effects of calcium-signaling antagonists. American journal of physiology. Lung cellular and molecular physiology. 292, L1444-L1451. doi:10.1152/ajplung.00162.2006. ISSN 1522-1504
We have previously examined the ability of air pollution particles (PM10) to promote release of the proinflammatory cytokine tumor necrosis factor- (TNF-) from human periphera...
The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4
Journal Article
Brown, D. M., HUTCHISON, L., DONALDSON, K., MACKENZIE, S., DICK, C., & STONE, V. (2007)
The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4. Toxicology Letters, 168(1), 1-6. doi:10.1016/j.toxlet.2006.10.016
Reactive oxygen species (ROS) have been implicated in various pulmonary diseases by causing direct injury to lung epithelial cells. Signalling activity of cells through transc...
Physiological variables and performance markers of serving soldiers from two “elite” units of the British Army.
Journal Article
Simpson, R. J., Gray, S., & Florida-James, G. (2006)
Physiological variables and performance markers of serving soldiers from two “elite” units of the British Army. Journal of Sports Sciences, 24, 597-604. https://doi.org/10.1080/02640410500230811
The aim of this study was to compare selected physiological variables and performance markers of soldiers from two “elite” units of the British Army. Ten soldiers from each of...
The effects of intensive, moderate and downhill treadmill running on human blood lymphocytes expressing the adhesion/activation molecules CD54 (ICAM-1), CD18 (β2 integrin) and CD53.
Journal Article
Simpson, R. J., Florida-James, G., Whyte, G. P., & Guy, K. (2006)
The effects of intensive, moderate and downhill treadmill running on human blood lymphocytes expressing the adhesion/activation molecules CD54 (ICAM-1), CD18 (β2 integrin) and CD53. European Journal of Applied Physiology, 97, 109-121. https://doi.org/10.1007/s00421-006-0146-4
This study examined the effects of intensive, moderate and downhill treadmill running on blood lymphocyte expression of adhesion/activation (AA) molecules. Trained subjects co...
Ultrafine particles cause cytoskeletal dysfunctions in macrophages: role of intracellular calcium.
Journal Article
Moller, W., Brown, D. M., Kreyling, L., & Stone, V. (2005)
Ultrafine particles cause cytoskeletal dysfunctions in macrophages: role of intracellular calcium. Particle and fibre toxicology, 2, 7. https://doi.org/10.1186/1743-8977-2-7
Background
Particulate air pollution is reported to cause adverse health effects in susceptible individuals. Since most of these particles are derived form combustion processe...
Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo.
Journal Article
Taylor, M. D., LeGoff, L., Harris, A., Malone, E. M., Allen, J. E., & Maizels, R. M. (2005)
Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. Journal of Immunology, 174, 4924-4933
Human filarial parasites cause chronic infection associated with long-term down-regulation of the host’s immune response. We show here that CD4+ T cell regulation is the main ...