Ovine trophoblasts express cathelicidin host defence peptide in response to infection
Journal Article
Coyle, C., Wheelhouse, N., Jacques, M., Longbottom, D., Svoboda, P., Pohl, J., …Barlow, P. G. (2016)
Ovine trophoblasts express cathelicidin host defence peptide in response to infection. Journal of Reproductive Immunology, 117, 10-16. https://doi.org/10.1016/j.jri.2016.06.006
Cationic host defence peptides (CHDP; also known as antimicrobial peptides) are key components of the immune response in the female reproductive tract. The role of the placent...
MAPK Activation Is Essential for Waddlia chondrophila Induced CXCL8 Expression in Human Epithelial Cells
Journal Article
Storrie, S., Longbottom, D., Barlow, P. G., & Wheelhouse, N. (2016)
MAPK Activation Is Essential for Waddlia chondrophila Induced CXCL8 Expression in Human Epithelial Cells. PLOS ONE, 11(3), https://doi.org/10.1371/journal.pone.0152193
Background
Waddlia chondrophila (W. chondrophila) is an emerging agent of respiratory and reproductive disease in humans and cattle. The organism is a member of the order Chla...
Waddlia chondrophila Infects and Multiplies in Ovine Trophoblast Cells Stimulating an Inflammatory Immune Response
Journal Article
Wheelhouse, N., Coyle, C., Barlow, P. G., Mitchell, S., Greub, G., Baszler, T., …Longbottom, D. (2014)
Waddlia chondrophila Infects and Multiplies in Ovine Trophoblast Cells Stimulating an Inflammatory Immune Response. PLOS ONE, 9(7), https://doi.org/10.1371/journal.pone.0102386
BACKGROUND
Waddlia chondrophila (W. chondrophila) is an emerging abortifacient organism which has been identified in the placentae of humans and cattle. The organism is a mem...