Challenges and priorities for modelling livestock health and pathogens in the context of climate change
Journal Article
Özkan, Ş., Vitali, A., Lacetera, N., Amon, B., Bannink, A., Bartley, D. J., …Kipling, R. P. (2016)
Challenges and priorities for modelling livestock health and pathogens in the context of climate change. Environmental Research, 151, 130-144. https://doi.org/10.1016/j.envres.2016.07.033
Climate change has the potential to impair livestock health, with consequences for animal welfare, productivity, greenhouse gas emissions, and human livelihoods and health. Mo...
MAPK Activation Is Essential for Waddlia chondrophila Induced CXCL8 Expression in Human Epithelial Cells
Journal Article
Storrie, S., Longbottom, D., Barlow, P. G., & Wheelhouse, N. (2016)
MAPK Activation Is Essential for Waddlia chondrophila Induced CXCL8 Expression in Human Epithelial Cells. PLOS ONE, 11(3), https://doi.org/10.1371/journal.pone.0152193
Background
Waddlia chondrophila (W. chondrophila) is an emerging agent of respiratory and reproductive disease in humans and cattle. The organism is a member of the order Chla...
Chlamydia-related Organisms: Infection in Ruminants and Potential for Zoonotic transmission
Journal Article
Wheelhouse, N., & Longbottom, D. (2015)
Chlamydia-related Organisms: Infection in Ruminants and Potential for Zoonotic transmission. Current Clinical Microbiology Reports, 2(1), 1-9. https://doi.org/10.1007/s40588-014-0011-x
The chlamydiae are a diverse group of obligate intracellular Gram-negative bacteria that are known to infect a wide variety of host species and are responsible for a wide rang...
An unusual presentation of Chlamydia pneumoniaeinfection in a Royal Python (Python regius)
Journal Article
Cope, I., Wheelhouse, N., Pocknell, A., Dagleish, M., & Summers, B. (2014)
An unusual presentation of Chlamydia pneumoniaeinfection in a Royal Python (Python regius). Veterinary record case reports, 2(1), https://doi.org/10.1136/vetreccr-2014-000086
Chlamydia species are a relatively newly recognised and emerging pathogen in reptile species. Chlamydia pneumoniae has been reported to cause infections in several snake speci...
Diagnosing the causes of ruminant abortion: where are we now?
Journal Article
Wheelhouse, N., & Dalgleish, M. (2014)
Diagnosing the causes of ruminant abortion: where are we now?. Veterinary Journal, 201(3), 243-244. https://doi.org/10.1016/j.tvjl.2014.05.042
Risk factors associated with Lawsonia intracellularis in English pig farms
Journal Article
Bae, J. K., Wieland, B., Sait, M., Longbottom, D., Smith, D. G. E., Alarcon, P. & Wheelhouse, N. (2013)
Risk factors associated with Lawsonia intracellularis in English pig farms. Veterinary Journal. 197(3), 707-11. doi:10.1016/j.tvjl.2013.03.020. ISSN 1090-0233
Porcine proliferative enteropathy (PPE) caused by the bacterium Lawsonia intracellularis causes considerable economic loss to the pig industry. The objective of this study was...
Processing of Chlamydia abortus polymorphic membrane protein 18D during the chlamydial developmental cycle
Journal Article
Wheelhouse, N. M., Sait, M., Aitchison, K., Livingstone, M., Wright, F., McLean, K., …Longbottom, D. (2012)
Processing of Chlamydia abortus polymorphic membrane protein 18D during the chlamydial developmental cycle. PLOS ONE, 7, https://doi.org/10.1371/journal.pone.0049190
BACKGROUND: Chlamydia possess a unique family of autotransporter proteins known as the Polymorphic membrane proteins (Pmps). While the total number of pmp genes varies between...
Expression patterns of five polymorphic membrane proteins during the Chlamydia abortus developmental cycle
Journal Article
Longbottom, D., Wheelhouse, N., Sait, M., Wilson, K., Aitchison, K., McLean, K., & Smith, D. G. E. (2012)
Expression patterns of five polymorphic membrane proteins during the Chlamydia abortus developmental cycle. Veterinary Microbiology, 160(3-4), 525-529. https://doi.org/10.1016/j.vetmic.2012.06.017
It has been suggested that polymorphic membrane proteins (Pmps) belonging to the Type V autotransporter protein family play an important role in the pathogenesis of Chlamydia ...
Involvement of Parachlamydia in bovine abortions in Scotland
Journal Article
Howie, F., Gidlow, J., Greub, G., Wheelhouse, N., Dagleish, M., & Longbottom, D. (2012)
Involvement of Parachlamydia in bovine abortions in Scotland. Veterinary Journal, 193(2), 586-588. https://doi.org/10.1016/j.tvjl.2012.01.008
Bovine abortion represents a major animal welfare issue and a cause of substantial economic loss yet the rate of successful diagnosis remains low. Chlamydia-related organisms ...
New challenges for vaccination to prevent chlamydial abortion in sheep
Journal Article
Entrican, G., Wheelhouse, N., Wattegedera, S. R., & Longbottom, D. (2012)
New challenges for vaccination to prevent chlamydial abortion in sheep. Comparative Immunology, Microbiology and Infectious Diseases, 35(3), 271-276. https://doi.org/10.1016/j.cimid.2011.12.001
Ovine enzootic abortion (OEA) is caused by the obligate intracellular Gram-negative bacterium Chlamydia abortus. OEA remains a common cause of infectious abortion in many shee...