9 results

BioGRID: A Resource for Studying Biological Interactions in Yeast: Table 1.

Journal Article
Oughtred, R., Chatr-aryamontri, A., Breitkreutz, B., Chang, C. S., Rust, J. M., Theesfeld, C. L., …Tyers, M. (2016)
BioGRID: A Resource for Studying Biological Interactions in Yeast: Table 1. Cold Spring Harbor protocols, 2016(1), pdb.top080754. https://doi.org/10.1101/pdb.top080754
The Biological General Repository for Interaction Datasets (BioGRID) is a freely available public database that provides the biological and biomedical research communities wit...

The BioGRID interaction database: 2015 update

Journal Article
Chatr-aryamontri, A., Breitkreutz, B., Oughtred, R., Boucher, L., Heinicke, S., Chen, D., …Tyers, M. (2015)
The BioGRID interaction database: 2015 update. Nucleic Acids Research, 43(D1), D470-D478. https://doi.org/10.1093/nar/gku1204
The Biological General Repository for Interaction Datasets (BioGRID: http://thebiogrid.org) is an open access database that houses genetic and protein interactions curated fro...

Monocyte chemoattractant protein-induced protein 1 impairs adipogenesis in 3T3-L1 cells

Journal Article
Lipert, B., Wegrzyn, P., Sell, H., Eckel, J., Winiarski, M., Budzynski, A., …Jura, J. (2014)
Monocyte chemoattractant protein-induced protein 1 impairs adipogenesis in 3T3-L1 cells. BBA - Molecular Cell Research, 1843(4), 780-788. https://doi.org/10.1016/j.bbamcr.2014.01.001
Monocyte chemoattractant protein-induced protein 1 (MCPIP1) encoded by the ZC3H12a gene (also known as Regnase-1) is involved in the regulation of degradation of mRNA of infla...

The BioGRID interaction database: 2013 update

Journal Article
Chatr-aryamontri, A., Breitkreutz, B., Heinicke, S., Boucher, L., Winter, A., Stark, C., …Tyers, M. (2013)
The BioGRID interaction database: 2013 update. Nucleic Acids Research, 41(D1), D816-D823. https://doi.org/10.1093/nar/gks1158
The Biological General Repository for Interaction Datasets (BioGRID: http//thebiogrid.org) is an open access archive of genetic and protein interactions that are curated from ...

P088 Involvement of NMDAR in chondrocyte cell death and matrix degeneration

Presentation / Conference
Ramage, L., Hardingham, G. & Salter, D. (2009, June)
P088 Involvement of NMDAR in chondrocyte cell death and matrix degeneration. Paper presented at 2nd Joint meeting of the Bone Research Society and the British Society for Matrix Biology, London
NMDA receptors (NMDAR) are expressed by chondrocytes in articular cartilage although their function is yet to be fully understood. NMDAR are ionotropic glutamate receptors whi...

Signalling cascades in mechanotransduction: cell-matrix interactions and mechanical loading

Journal Article
Ramage, L., Nuki, G., & Salter, D. M. (2009)
Signalling cascades in mechanotransduction: cell-matrix interactions and mechanical loading. Scandinavian Journal of Medicine and Science in Sports, 19(4), 457-469. https://doi.org/10.1111/j.1600-0838.2009.00912.x
Mechanical loading of articular cartilage stimulates the metabolism of resident chondrocytes and induces the synthesis of molecules to maintain the integrity of the cartilage....

Induction of apoptosis with tobacco smoke and related products in A549 lung epithelial cells in vitro

Journal Article
Ramage, L., Jones, A. C., & Whelan, C. J. (2006)
Induction of apoptosis with tobacco smoke and related products in A549 lung epithelial cells in vitro. Journal of Inflammation, 3(1), 3. https://doi.org/10.1186/1476-9255-3-3
Background This study has investigated the ability of tobacco smoke, and ingredients of tobacco smoke, to induce apoptosis in the airway epithelial cell line A549. Method A549...

Expression of C-Reactive Protein in Human Lung Epithelial Cells and Upregulation by Cytokines and Carbon Particles

Journal Article
Ramage, L., Proudfoot, L., & Guy, K. (2004)
Expression of C-Reactive Protein in Human Lung Epithelial Cells and Upregulation by Cytokines and Carbon Particles. Inhalation Toxicology, 16(9), 607-613. https://doi.org/10.1080/08958370490464599
C-reactive protein (CRP) is the prototypic human acute-phase protein and is found at increased levels in the blood during episodes of inflammation. CRP was generally thought t...

Expression of C-Reactive Protein and Heat-Shock Protein-70 in the Lung Epithelial Cell Line A549, in Response to PM10 Exposure

Journal Article
Ramage, L., & Guy, K. (2004)
Expression of C-Reactive Protein and Heat-Shock Protein-70 in the Lung Epithelial Cell Line A549, in Response to PM10 Exposure. Inhalation Toxicology, 16(6-7), 447-452. https://doi.org/10.1080/08958370490439614
Increased levels of C-reactive protein (CRP) and heat-shock protein-70 (Hsp70) in plasma are known to be associated with an increased risk of cardiovascular disease. In this s...