5 results

Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines.

Journal Article
Brown, D. M., Wilson, M. R., MacNee, W., Stone, V., & Donaldson, K. (2001)
Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines. Toxicology and Applied Pharmacology, 175, 191-199. https://doi.org/10.1006/taap.2001.9240
Studies into the effects of ultrafine particles in the lung have shown adverse effects considered to be due in part to the particle size. Air pollution particles (PM10) are as...

The neuropsychiatric sequelae of mercury poisoning. The Mad Hatter's disease revisited

Journal Article
O'Carroll, R. E., Masterton, G., Dougall, N., Ebmeier, K. P., & Goodwin, G. M. (1995)
The neuropsychiatric sequelae of mercury poisoning. The Mad Hatter's disease revisited. British Journal of Psychiatry, 167(1), 95-98. doi:10.1192/bjp.167.1.95
BACKGROUND The detailed effects of mercury poisoning on cognitive function, brain anatomy and regional brain function are largely unknown. We report the case of a 38-year-old ...

Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats

Journal Article
McQueen, D. S., Bond, S. M., Smith, P. J., Balali-Mood, K., & Smart, D. (2004)
Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats. European Journal of Pharmacology, 491(2-3), 181-189. https://doi.org/10.1016/j.ejphar.2004.03.045
The results of vasorespiratory studies in rats anaesthetised with pentobarbital show that (±) cannabidiol, a cannabinoid that lacks psychotropic actions and is inactive at can...

Alpha-1-acid glycoprotein expressed in the plasma of chronic myeloid leukemia patients does not mediate significant in vitro resistance to STI571.

Journal Article
Jørgensen, H. G., Elliott, M. A., Allan, E. K., Carr, C. E., Holyoake, T. L. & Smith, K. (2002)
Alpha-1-acid glycoprotein expressed in the plasma of chronic myeloid leukemia patients does not mediate significant in vitro resistance to STI571. Blood. 99, 713-715. doi:10.1182/blood.V99.2.713. ISSN 0006-4971
Despite the efficacy of STI571 (Glivec, Novartis, Basle, Switzerland) in treating chronic myeloid leukemia (CML), drug resistance has already been noted both in vitro and in v...

Uptake of99mTc-exametazime shown by single photon emission computerized tomography in obsessive-compulsive disorder compared with major depression and normal controls

Journal Article
Edmonstone, Y., Austin, M., Prentice, N., Dougall, N., Freeman, C. P. L., Ebmeier, K. P. & Goodwin, G. M. (1994)
Uptake of99mTc-exametazime shown by single photon emission computerized tomography in obsessive-compulsive disorder compared with major depression and normal controls. Acta psychiatrica Scandinavica. 90(4), 298-303. doi:10.1111/j.1600-0447.1994.tb01597.x. ISSN 0001-690X
Twelve patients with obsessive-compulsive disorder (OCD) were investigated at rest using single photon emission computerized tomography with 99mTc-exametazime. The uptake of 9...