The binding ability of alpha-1-acid glycoprotein as a mechanism of resistance to methadone.
Thesis
Behan, J. L. The binding ability of alpha-1-acid glycoprotein as a mechanism of resistance to methadone. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/4446
Dependence on heroin and other opioids represents a considerable problem worldwide. There is a continual need to improve therapy and/ or find more efficacious alternatives if...
Characterisation of class II and III fructose bisphosphatases in Clostridium acetobutylicum ATCC 824
Thesis
Almohaish, A. A. Characterisation of class II and III fructose bisphosphatases in Clostridium acetobutylicum ATCC 824. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/5692
In low GC Gram-positive bacteria, the phenomenon of carbon catabolite repression is dependent on a metabolite-activated bifunctional protein kinase/phosphorylase. In Clostridi...
Nanoparticle interactions with zinc and iron: Implications for toxicology and inflammation
Journal Article
Wilson, M. R., Foucaud, L., Barlow, P. G., Hutchison, G. R., Sales, J., Simpson, R. J., & Stone, V. (2007)
Nanoparticle interactions with zinc and iron: Implications for toxicology and inflammation. Toxicology and Applied Pharmacology, 225(1), 80-89. https://doi.org/10.1016/j.taap.2007.07.012
Particulate air pollution (PM10) consists of a mixture of components, including nanoparticles and metals. Studies from our laboratory have demonstrated that transition metals ...
Development of a method for the detection of GHB and other drugs using a handheld Raman Spectroscopy device
Thesis
O'Connor, L. Development of a method for the detection of GHB and other drugs using a handheld Raman Spectroscopy device. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/5260
The main piece of legislation which addresses illicit drugs in the UK is the Misuse of Drugs Act 1971. The Act was designed to prevent the use of drugs which are 'capable of h...
Development of a Caenorhabditis elegans model for the assessment of toxicity and its application in testing novel anthelmintics.
Thesis
Oluwadare, E. Development of a Caenorhabditis elegans model for the assessment of toxicity and its application in testing novel anthelmintics. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/Output/1036075
The nematode Caenorhabditis elegans is an alternative model used in biomedical research for the investigation of descriptive and mechanistic toxicity assessment of chemicals. ...
Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential
Journal Article
Sharma, A., Goring, A., Staines, K., Emery, R., Pitsillides, A. A., Oreffo, R. O., …Clarkin, C. E. (2020)
Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential. Matrix Biology Plus, 5, https://doi.org/10.1016/j.mbplus.2019.100018
Mineralization of bone is achieved by the sequential maturation of the immature amorphous calcium phase to mature hydroxyapatite and is central to the process of bone developm...
Immortality, but not oncogenic transformation, of primary human cells leads to epigenetic reprogramming of DNA methylation and gene expression
Journal Article
Gordon, K., Clouaire, T., Bao, X. X., Kemp, S. E., Xenophontos, M., de Las Heras, J. I., & Stancheva, I. (2014)
Immortality, but not oncogenic transformation, of primary human cells leads to epigenetic reprogramming of DNA methylation and gene expression. Nucleic Acids Research, 42(6), 3529-3541. https://doi.org/10.1093/nar/gkt1351
Tumourigenic transformation of normal cells into cancer typically involves several steps resulting in acquisition of unlimited growth potential, evasion of apoptosis and non-r...
Disastrous performance of NanoCote/Aqua Based antimicrobial paint in a hospital setting
Journal Article
Ramsden, J., Reid, M., Whatley, V., & Dancer, S. (2016)
Disastrous performance of NanoCote/Aqua Based antimicrobial paint in a hospital setting. Journal of Biological Physics and Chemistry, 16(3), 131-136. https://doi.org/10.4024/16ra16a.jbpc.16.03
Attempts are being made to incorporate copper into clear varnish in order to coat environmental surfaces in hospitals with the long-term goal of reducing healthcare-acquired i...
Expression of pro-inflammatory proteins in the lung
epithelial cell line A549, in response to cytokine, and
environmental particle exposure.
Thesis
Ramage, L. environmental particle exposure. (Thesis)
Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/2778
This thesis investigates the effects of various inflammatory stimuli, including cytokines and air pollution particles, on the expression and secretion of various proinflammato...
A comparison of five rapid direct toxicity assessment methods to determine toxicity of pollutants to activated sludge
Journal Article
de la Sota, A., Aspichueta, E., Dalzell, D., Dalzell, D., Alte, S., Aspichueta, E., …Christofi, N. (2002)
A comparison of five rapid direct toxicity assessment methods to determine toxicity of pollutants to activated sludge. Chemosphere, 47(5), 535-545. doi:10.1016/s0045-6535(01)00331-9
Five rapid direct toxicity assessment methods were used in three European partner countries to determine the toxicity of single toxicants, mixed toxicants and real industrial ...