Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl)pyrimidine-based derivatives as dual BRAFV600E/p38α inhibitors
Journal Article
Ali, E. M., El-Telbany, R. F. A., Abdel-Maksoud, M. S., Ammar, U. M., Mersal, K. I., Zaraei, S., …Oh, C. (2021)
Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl)pyrimidine-based derivatives as dual BRAFV600E/p38α inhibitors. European Journal of Medicinal Chemistry, 215, Article 113277. https://doi.org/10.1016/j.ejmech.2021.113277
The synergistic effect of dual inhibition of serine/threonine protein kinases that are involved in the same signalling pathway of the diseases can exert superior biological be...
Clinical judgement in violence risk assessment
Journal Article
Murray, J., & Thomson, M. E. (2010)
Clinical judgement in violence risk assessment. Europe's journal of psychology, 6(1), 128-149. https://doi.org/10.5964/ejop.v6i1.175
The present article discusses the three main approaches to violence risk assessment, clinical judgement, actuarial assessment, and structured clinical judgement, informing the...
Hypomorphic conditional deletion of E11/Podoplanin reveals a role in osteocyte dendrite elongation.
Journal Article
Buttle, D. J., Pitsillides, A. A., Staines, K. A., Javaheri, B., Hohenstein, P., Fleming, R., …Farquharson, C. (2017)
Hypomorphic conditional deletion of E11/Podoplanin reveals a role in osteocyte dendrite elongation. Journal of Cellular Physiology, 232(11), 3006-3019. https://doi.org/10.1002/jcp.25999
The transmembrane glycoprotein E11/Podoplanin (Pdpn) has been implicated in the initial stages of osteocyte differentiation. However, its precise function and regulatory mecha...
The Practice Session - Talent Development
Book Chapter
Martindale, R. (2014)
The Practice Session - Talent Development
Talent identification and development is an important part of youth sports coaching and it is clear that coaches and significant others play an important role at every stage. ...
Creatine-Kinase- and exercise-related muscle damage implications for muscle performance and recovery
Journal Article
Baird, M. F., Graham, S. M., Baker, J. S., & Bickerstaff, G. F. (2012)
Creatine-Kinase- and exercise-related muscle damage implications for muscle performance and recovery. Journal of Nutrition and Metabolism, 2012, 1-13. https://doi.org/10.1155/2012/960363
The appearance of creatine kinase (CK) in blood has been generally considered to be an indirect marker of muscle damage, particularly for diagnosis of medical conditions such ...
Exercise intervention for patients surgically treated for Non-Small Cell Lung Cancer (NSCLC): A systematic review
Journal Article
Crandall, K., Maguire, R., Campbell, A., & Kearney, N. (2014)
Exercise intervention for patients surgically treated for Non-Small Cell Lung Cancer (NSCLC): A systematic review. Surgical Oncology, 23(1), 17-30. https://doi.org/10.1016/j.suronc.2014.01.001
AbstractBackground Surgery remains the best curative option for appropriately selected patients with lung cancer. Evidence suggests that improving cardiovascular fitness and f...
The sediment carbon stocks of intertidal seagrass meadows in Scotland
Journal Article
Potouroglou, M., Whitlock, D., Milatovic, L., MacKinnon, G., Kennedy, H., Diele, K., & Huxham, M. (2021)
The sediment carbon stocks of intertidal seagrass meadows in Scotland. Estuarine, Coastal and Shelf Science, 258, Article 107442. https://doi.org/10.1016/j.ecss.2021.107442
Seagrasses are highly productive ecosystems and hotspots for biodiversity, providing a plethora of benefits to the environment and to people. Their value in sequestering and s...
The effects of menstrual cycle phases on running repeated sprint ability
Thesis
Di Nicola, S. The effects of menstrual cycle phases on running repeated sprint ability. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/Output/2808661
Female participation in regular sport activities has increased in recent years, yet their representation in the sports and exercise science literature remains low. Therefore, ...
A Biomechanical Analysis of British Army Foot-Drill: Implications of Lower-Extremity Musculoskeletal Injury in Age-matched Civilian Men and Women
Thesis
Rawcliffe, A. J. A Biomechanical Analysis of British Army Foot-Drill: Implications of Lower-Extremity Musculoskeletal Injury in Age-matched Civilian Men and Women. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/Output/2090019
British Army foot-drill may be a risk factor for musculoskeletal (MSK) injury. However, limited empirical research exists quantifying lower-extremity risk factors of foot-dril...
Firewood usage and indoor air pollution from traditional cooking fires in Gazi Bay, Kenya
Journal Article
Jung, J., & Huxham, M. (2019)
Firewood usage and indoor air pollution from traditional cooking fires in Gazi Bay, Kenya. Bioscience Horizons, 11, https://doi.org/10.1093/biohorizons/hzy014
Mangroves are increasingly being recognised for the important ecosystem services they provide, including carbon fixation, shoreline protection and fisheries habitats. In addit...