MAPK Activation Is Essential for Waddlia chondrophila Induced CXCL8 Expression in Human Epithelial Cells
Journal Article
Storrie, S., Longbottom, D., Barlow, P. G., & Wheelhouse, N. (2016)
MAPK Activation Is Essential for Waddlia chondrophila Induced CXCL8 Expression in Human Epithelial Cells. PLOS ONE, 11(3), https://doi.org/10.1371/journal.pone.0152193
Background
Waddlia chondrophila (W. chondrophila) is an emerging agent of respiratory and reproductive disease in humans and cattle. The organism is a member of the order Chla...
An unusual presentation of Chlamydia pneumoniaeinfection in a Royal Python (Python regius)
Journal Article
Cope, I., Wheelhouse, N., Pocknell, A., Dagleish, M., & Summers, B. (2014)
An unusual presentation of Chlamydia pneumoniaeinfection in a Royal Python (Python regius). Veterinary record case reports, 2(1), https://doi.org/10.1136/vetreccr-2014-000086
Chlamydia species are a relatively newly recognised and emerging pathogen in reptile species. Chlamydia pneumoniae has been reported to cause infections in several snake speci...
Evidence of members of the Chlamydiales in bovine abortions in England and Wales
Journal Article
Wheelhouse, N., Mearns, R., Willoughby, K., Wright, E., Turnbull, D., & Longbottom, D. (2015)
Evidence of members of the Chlamydiales in bovine abortions in England and Wales. Veterinary Record, 176, 465. https://doi.org/10.1136/vr.103075
Despite the economical importance and welfare issues associated with bovine abortion, as well as the potential zoonotic implications, the rate of diagnosis remains low with a ...
New challenges for vaccination to prevent chlamydial abortion in sheep
Journal Article
Entrican, G., Wheelhouse, N., Wattegedera, S. R., & Longbottom, D. (2012)
New challenges for vaccination to prevent chlamydial abortion in sheep. Comparative Immunology, Microbiology and Infectious Diseases, 35(3), 271-276. https://doi.org/10.1016/j.cimid.2011.12.001
Ovine enzootic abortion (OEA) is caused by the obligate intracellular Gram-negative bacterium Chlamydia abortus. OEA remains a common cause of infectious abortion in many shee...
Evidence of Chlamydophila abortus vaccine strain 1B as a possible cause of ovine enzootic abortion
Journal Article
Wheelhouse, N., Aitchison, K., Laroucau, K., Thomson, J., & Longbottom, D. (2010)
Evidence of Chlamydophila abortus vaccine strain 1B as a possible cause of ovine enzootic abortion. Vaccine, 28(35), 5657-5663. https://doi.org/10.1016/j.vaccine.2010.04.114
Chlamydophila abortus, the agent of ovine enzootic abortion (OEA), is a major cause of lamb mortality worldwide. Disease can be controlled through the use of vaccines based on...
Chlamydia-related Organisms: Infection in Ruminants and Potential for Zoonotic transmission
Journal Article
Wheelhouse, N., & Longbottom, D. (2015)
Chlamydia-related Organisms: Infection in Ruminants and Potential for Zoonotic transmission. Current Clinical Microbiology Reports, 2(1), 1-9. https://doi.org/10.1007/s40588-014-0011-x
The chlamydiae are a diverse group of obligate intracellular Gram-negative bacteria that are known to infect a wide variety of host species and are responsible for a wide rang...
Challenges and priorities for modelling livestock health and pathogens in the context of climate change
Journal Article
Özkan, Ş., Vitali, A., Lacetera, N., Amon, B., Bannink, A., Bartley, D. J., …Kipling, R. P. (2016)
Challenges and priorities for modelling livestock health and pathogens in the context of climate change. Environmental Research, 151, 130-144. https://doi.org/10.1016/j.envres.2016.07.033
Climate change has the potential to impair livestock health, with consequences for animal welfare, productivity, greenhouse gas emissions, and human livelihoods and health. Mo...
Immunological paradigms and the pathogenesis of ovine chlamydial abortion
Journal Article
Entrican, G., Wattegedera, S., Wheelhouse, N., Allan, A., & Rocchi, M. (2010)
Immunological paradigms and the pathogenesis of ovine chlamydial abortion. American Journal of Reproductive Immunology, 64(4), 287-294. https://doi.org/10.1111/j.1600-0897.2010.00907.x
Successful mammalian pregnancy involves complex immunological interactions between the mother and foetus that are not yet fully understood. A number of immunological paradigms...
Chlamydia in cases of bovine abortion in Ireland
Journal Article
Wheelhouse, N., Longbottom, D., & O'Donovan, J. (2014)
Chlamydia in cases of bovine abortion in Ireland. Veterinary Record, 174(22), 560-561. https://doi.org/10.1136/vr.g3567
We report the findings of a preliminary investigation into chlamydial involvement in cases of bovine abortion in Ireland. Chlamydia abortus has long been recognised as a known...
Involvement of Parachlamydia in bovine abortions in Scotland
Journal Article
Howie, F., Gidlow, J., Greub, G., Wheelhouse, N., Dagleish, M., & Longbottom, D. (2012)
Involvement of Parachlamydia in bovine abortions in Scotland. Veterinary Journal, 193(2), 586-588. https://doi.org/10.1016/j.tvjl.2012.01.008
Bovine abortion represents a major animal welfare issue and a cause of substantial economic loss yet the rate of successful diagnosis remains low. Chlamydia-related organisms ...