The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4
Journal Article
Brown, D. M., HUTCHISON, L., DONALDSON, K., MACKENZIE, S., DICK, C., & STONE, V. (2007)
The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4. Toxicology Letters, 168(1), 1-6. doi:10.1016/j.toxlet.2006.10.016
Reactive oxygen species (ROS) have been implicated in various pulmonary diseases by causing direct injury to lung epithelial cells. Signalling activity of cells through transc...
Effects of PM10 in human peripheral blood monocytes and J774 macrophages.
Journal Article
Brown, D. M., Donaldson, K., & Stone, V. (2004)
Effects of PM10 in human peripheral blood monocytes and J774 macrophages. Respiratory Research, 5, 29. https://doi.org/10.1186/1465-9921-5-29
The effects of PM10, one of the components of particulate air pollution, was investigated using human monocytes and a mouse macrophage cell line (J774). The study aimed to inv...
Ultrafine particles cause cytoskeletal dysfunctions in macrophages: role of intracellular calcium.
Journal Article
Moller, W., Brown, D. M., Kreyling, L., & Stone, V. (2005)
Ultrafine particles cause cytoskeletal dysfunctions in macrophages: role of intracellular calcium. Particle and fibre toxicology, 2, 7. https://doi.org/10.1186/1743-8977-2-7
Background
Particulate air pollution is reported to cause adverse health effects in susceptible individuals. Since most of these particles are derived form combustion processe...
The effects of intensive, moderate and downhill treadmill running on human blood lymphocytes expressing the adhesion/activation molecules CD54 (ICAM-1), CD18 (β2 integrin) and CD53.
Journal Article
Simpson, R. J., Florida-James, G., Whyte, G. P., & Guy, K. (2006)
The effects of intensive, moderate and downhill treadmill running on human blood lymphocytes expressing the adhesion/activation molecules CD54 (ICAM-1), CD18 (β2 integrin) and CD53. European Journal of Applied Physiology, 97, 109-121. https://doi.org/10.1007/s00421-006-0146-4
This study examined the effects of intensive, moderate and downhill treadmill running on blood lymphocyte expression of adhesion/activation (AA) molecules. Trained subjects co...
Consequences for the male fetus: Time windows of testosterone action and susceptibility to disorders of ‘masculinisation’
Journal Article
Sharpe, R. M., Scott, H. M., Hutchison, G., Walker, M., McKinnell, C., Saunders, P., & Welsh, M. (2007)
Consequences for the male fetus: Time windows of testosterone action and susceptibility to disorders of ‘masculinisation’. Toxicology, 240(3), 144-145. https://doi.org/10.1016/j.tox.2007.06.027
Conference abstract in Proceedings of the Annual Congress of The British Toxicology Society.
Anti-inflammatory responses and oxidative stress in Nippostrongylus brasiliensis-induced pulmonary inflammation.
Journal Article
McNeil, K. S., Knox, D. P. & Proudfoot, L. (2002)
Anti-inflammatory responses and oxidative stress in Nippostrongylus brasiliensis-induced pulmonary inflammation. Parasite Immunology. 24, 15-22. doi:10.1046/j.0141-9838.2001.00428.x. ISSN 0141-9838
Migration of L3 larvae of Nippostrongylus brasiliensis through the lungs of the rat, during primary infection, was studied at 24 h, 72 h and 8 days. At 24 h p.i., there was ev...
Genomic mapping and evolution of human GABAA receptor subunit gene clusters
Journal Article
Bailey, M. E. S., Matthews, D. A., Riley, B. P., Albrecht, B. E., Kostrzewa, M., Hicks, A. A., …Johnson, K. J. (1999)
Genomic mapping and evolution of human GABAA receptor subunit gene clusters. Mammalian Genome, 10(8), 839-843. https://doi.org/10.1007/s003359901101
No abstract available.
The effects of macrophage migratory inhibitory factor on acute-phase protein production in primary human hepatocytes
Journal Article
Wheelhouse, N. M., Dowidar, N., Dejong, C. H. C., Garden, O. J., Powell, J. J., Barber, M. D., …Ross, J. A. (2006)
The effects of macrophage migratory inhibitory factor on acute-phase protein production in primary human hepatocytes. International Journal of Molecular Medicine, 18(5), 957-961. https://doi.org/10.3892/ijmm.18.5.957
Macrophage inhibitory factor (MIF) is a pituitary peptide released during the physiological stress response, a T-cell product secreted during the antigen-specific response and...