The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.
Journal Article
Palmer, C., Cotton, L., & Henley, J. M. (2005)
The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Pharmacological Reviews, 57, 253-277. https://doi.org/10.1124/pr.57.2.7
-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) are of fundamental importance in the brain. They are responsible for the majority of fast excitatory synapti...
An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis.
Journal Article
Brown, D. M., Kinloch, I. A., Bangert, U., Windle, A., Walter, D. M., Walker, G. S., …Stone, V. (2007)
An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis. Carbon, 45, 1743-1756. https://doi.org/10.1016/j.carbon.2007.05.011
There has been little information to date based on the potential health effects and hazards associated with the inhalation of carbon nanofibrous materials by workers despite t...
What are the threats from antimicrobial resistance for maternity units in low- and middle- income countries?
Journal Article
Graham, W. J., Afsana, K., Campbell, O. M. R., Graham, W. J., Morrison, E., Dancer, S., …Woodd, S. (2016)
What are the threats from antimicrobial resistance for maternity units in low- and middle- income countries?. Global Health Action, 9(1), 33381. https://doi.org/10.3402/gha.v9.33381
No abstract available.
The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4
Journal Article
Brown, D. M., HUTCHISON, L., DONALDSON, K., MACKENZIE, S., DICK, C., & STONE, V. (2007)
The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4. Toxicology Letters, 168(1), 1-6. doi:10.1016/j.toxlet.2006.10.016
Reactive oxygen species (ROS) have been implicated in various pulmonary diseases by causing direct injury to lung epithelial cells. Signalling activity of cells through transc...
Variation in hospital cleaning practice and process in Australian hospitals: A structured mapping exercise
Journal Article
Mitchell, B. G., Farrington, A., Allen, M., Gardner, A., Hall, L., Barnett, A. G., …Graves, N. (2017)
Variation in hospital cleaning practice and process in Australian hospitals: A structured mapping exercise. Infection, Disease & Health, https://doi.org/10.1016/j.idh.2017.08.001
Background
The purpose of this paper is to highlight the range of cleaning practices and processes in 11 Australian hospitals and to discuss the challenges this variation pose...
Interactions between ultrafine particles and transition metals in vivo and in vitro.
Journal Article
Wilson, M. R., Lightbody, J., Donaldson, K., Sales, J., & Stone, V. (2002)
Interactions between ultrafine particles and transition metals in vivo and in vitro. Toxicology and Applied Pharmacology, 184, 172-179. https://doi.org/10.1006/taap.2002.9501
Both the ultrafine particle and transition metal components of particulate air pollution (PM10) have been hypothesized to be important factors in determining toxicity and pote...
Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines.
Journal Article
Brown, D. M., Wilson, M. R., MacNee, W., Stone, V., & Donaldson, K. (2001)
Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines. Toxicology and Applied Pharmacology, 175, 191-199. https://doi.org/10.1006/taap.2001.9240
Studies into the effects of ultrafine particles in the lung have shown adverse effects considered to be due in part to the particle size. Air pollution particles (PM10) are as...
The intermediate filament protein, vimentin, is a regulator of NOD2 activity
Journal Article
Stevens, C., Henderson, P., Nimmo, E. R., Soares, D. C., Dogan, B., Simpson, K. W., …Satsangi, J. (2013)
The intermediate filament protein, vimentin, is a regulator of NOD2 activity. Gut, 62(5), 695-707. https://doi.org/10.1136/gutjnl-2011-301775
Objective Mutations in the nucleotide-binding oligomerisation domain-containing protein 2 (NOD2) gene remain the strongest genetic determinants for Crohn's disease (CD). Havin...
Is it worth screening elective orthopaedic patients for carriage of Staphylococcus aureus ? A part-retrospective case–control study in a Scottish hospital
Journal Article
Dancer, S. J., Christison, F., Eslami, A., Gregori, A., Miller, R., Perisamy, K., …Graves, N. (2016)
Is it worth screening elective orthopaedic patients for carriage of Staphylococcus aureus ? A part-retrospective case–control study in a Scottish hospital. BMJ Open, 6(9), https://doi.org/10.1136/bmjopen-2016-011642
Background With recent focus on methicillin-resistant Staphylococcus aureus (MRSA) screening, methicillin-susceptible S. aureus (MSSA) has been overlooked. MSSA infections are...
Effects of PM10 in human peripheral blood monocytes and J774 macrophages.
Journal Article
Brown, D. M., Donaldson, K., & Stone, V. (2004)
Effects of PM10 in human peripheral blood monocytes and J774 macrophages. Respiratory Research, 5, 29. https://doi.org/10.1186/1465-9921-5-29
The effects of PM10, one of the components of particulate air pollution, was investigated using human monocytes and a mouse macrophage cell line (J774). The study aimed to inv...